Nakayama K - Search Results

1

Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2.

Nakayama K, Gazdoiu S, Abraham R, Pan ZQ, Ronai Z. Nakayama K, et al. Biochem J. 2007 Jan 1;401(1):217-26. doi: 10.1042/BJ20061135. Biochem J. 2007. PMID: 16958618 Free PMC article.

2

[Ubiquitin system in hypoxia response].

Nakayama K, Ronai Z. Nakayama K, et al. Tanpakushitsu Kakusan Koso. 2006 Aug;51(10 Suppl):1309-15. Tanpakushitsu Kakusan Koso. 2006. PMID: 16922393 Review. Japanese. No abstract available.

3

Regulation of the ring finger E3 ligase Siah2 by p38 MAPK.

Khurana A, Nakayama K, Williams S, Davis RJ, Mustelin T, Ronai Z. Khurana A, et al. Among authors: nakayama k. J Biol Chem. 2006 Nov 17;281(46):35316-26. doi: 10.1074/jbc.M606568200. Epub 2006 Sep 25. J Biol Chem. 2006. PMID: 17003045 Free PMC article.

4

The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways.

Qi J, Nakayama K, Gaitonde S, Goydos JS, Krajewski S, Eroshkin A, Bar-Sagi D, Bowtell D, Ronai Z. Qi J, et al. Among authors: nakayama k. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16713-8. doi: 10.1073/pnas.0804063105. Epub 2008 Oct 22. Proc Natl Acad Sci U S A. 2008. PMID: 18946040 Free PMC article.

5

The ubiquitin ligase Siah2 and the hypoxia response.

Nakayama K, Qi J, Ronai Z. Nakayama K, et al. Mol Cancer Res. 2009 Apr;7(4):443-51. doi: 10.1158/1541-7786.MCR-08-0458. Mol Cancer Res. 2009. PMID: 19372575 Free PMC article. Review.

6

Siah: new players in the cellular response to hypoxia.

Nakayama K, Ronai Z. Nakayama K, et al. Cell Cycle. 2004 Nov;3(11):1345-7. doi: 10.4161/cc.3.11.1207. Epub 2004 Nov 6. Cell Cycle. 2004. PMID: 15492505

7

Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors.

Qi J, Nakayama K, Cardiff RD, Borowsky AD, Kaul K, Williams R, Krajewski S, Mercola D, Carpenter PM, Bowtell D, Ronai ZA. Qi J, et al. Among authors: nakayama k. Cancer Cell. 2010 Jul 13;18(1):23-38. doi: 10.1016/j.ccr.2010.05.024. Cancer Cell. 2010. PMID: 20609350 Free PMC article.

8

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia.

Nakayama K, Frew IJ, Hagensen M, Skals M, Habelhah H, Bhoumik A, Kadoya T, Erdjument-Bromage H, Tempst P, Frappell PB, Bowtell DD, Ronai Z. Nakayama K, et al. Cell. 2004 Jun 25;117(7):941-52. doi: 10.1016/j.cell.2004.06.001. Cell. 2004. PMID: 15210114 Free article.

9

RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization.

Didier C, Broday L, Bhoumik A, Israeli S, Takahashi S, Nakayama K, Thomas SM, Turner CE, Henderson S, Sabe H, Ronai Z. Didier C, et al. Among authors: nakayama k. Mol Cell Biol. 2003 Aug;23(15):5331-45. doi: 10.1128/MCB.23.15.5331-5345.2003. Mol Cell Biol. 2003. PMID: 12861019 Free PMC article.

10

Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity.

Kikuchi D, Minamishima YA, Nakayama K. Kikuchi D, et al. Among authors: nakayama k. Biochem Biophys Res Commun. 2014 Aug 22;451(2):288-94. doi: 10.1016/j.bbrc.2014.07.114. Epub 2014 Aug 1. Biochem Biophys Res Commun. 2014. PMID: 25088999

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