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Human glioma growth is controlled by microRNA-10b.
Gabriely G, Yi M, Narayan RS, Niers JM, Wurdinger T, Imitola J, Ligon KL, Kesari S, Esau C, Stephens RM, Tannous BA, Krichevsky AM. Gabriely G, et al. Among authors: narayan rs. Cancer Res. 2011 May 15;71(10):3563-72. doi: 10.1158/0008-5472.CAN-10-3568. Epub 2011 Apr 6. Cancer Res. 2011. PMID: 21471404 Free PMC article.
A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities.
Narayan RS, Molenaar P, Teng J, Cornelissen FMG, Roelofs I, Menezes R, Dik R, Lagerweij T, Broersma Y, Petersen N, Marin Soto JA, Brands E, van Kuiken P, Lecca MC, Lenos KJ, In 't Veld SGJG, van Wieringen W, Lang FF, Sulman E, Verhaak R, Baumert BG, Stalpers LJA, Vermeulen L, Watts C, Bailey D, Slotman BJ, Versteeg R, Noske D, Sminia P, Tannous BA, Wurdinger T, Koster J, Westerman BA. Narayan RS, et al. Nat Commun. 2020 Jun 10;11(1):2935. doi: 10.1038/s41467-020-16735-2. Nat Commun. 2020. PMID: 32523045 Free PMC article.
Identification of MEK162 as a Radiosensitizer for the Treatment of Glioblastoma.
Narayan RS, Gasol A, Slangen PLG, Cornelissen FMG, Lagerweij T, Veldman HYYE, Dik R, van den Berg J, Slotman BJ, Würdinger T, Haas-Kogan DA, Stalpers LJA, Baumert BG, Westerman BA, Theys J, Sminia P. Narayan RS, et al. Mol Cancer Ther. 2018 Feb;17(2):347-354. doi: 10.1158/1535-7163.MCT-17-0480. Epub 2017 Sep 27. Mol Cancer Ther. 2018. PMID: 28958992
WINDOW consortium: A path towards increased therapy efficacy against glioblastoma.
Abdul KU, Houweling M, Svensson F, Narayan RS, Cornelissen FMG, Küçükosmanoglu A, Metzakopian E, Watts C, Bailey D, Wurdinger T, Westerman BA. Abdul KU, et al. Among authors: narayan rs. Drug Resist Updat. 2018 Sep;40:17-24. doi: 10.1016/j.drup.2018.10.001. Epub 2018 Oct 30. Drug Resist Updat. 2018. PMID: 30439622 Review.
Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma.
Bikhezar F, de Kruijff RM, van der Meer AJGM, Torrelo Villa G, van der Pol SMA, Becerril Aragon G, Gasol Garcia A, Narayan RS, de Vries HE, Slotman BJ, Denkova AG, Sminia P. Bikhezar F, et al. Among authors: narayan rs. J Neurooncol. 2020 Jan;146(2):239-246. doi: 10.1007/s11060-019-03365-y. Epub 2019 Dec 24. J Neurooncol. 2020. PMID: 31875307 Free PMC article.
NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor.
Galvani E, Sun J, Leon LG, Sciarrillo R, Narayan RS, Sjin RT, Lee K, Ohashi K, Heideman DA, Alfieri RR, Heynen GJ, Bernards R, Smit EF, Pao W, Peters GJ, Giovannetti E. Galvani E, et al. Among authors: narayan rs. Oncotarget. 2015 Dec 15;6(40):42717-32. doi: 10.18632/oncotarget.3956. Oncotarget. 2015. PMID: 26015408 Free PMC article.
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