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Page 1
Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious.
Sônego F, Castanheira FV, Ferreira RG, Kanashiro A, Leite CA, Nascimento DC, Colón DF, Borges Vde F, Alves-Filho JC, Cunha FQ. Sônego F, et al. Among authors: nascimento dc. Front Immunol. 2016 Apr 26;7:155. doi: 10.3389/fimmu.2016.00155. eCollection 2016. Front Immunol. 2016. PMID: 27199981 Free PMC article. Review.
Divergent role of heme oxygenase inhibition in the pathogenesis of sepsis.
Freitas A, Alves-Filho JC, Trevelin SC, Spiller F, Suavinha MM, Nascimento DC, Pestana CR, Dal-Secco D, Sônego F, Czaikoski PG, Curti C, Barja-Fidalgo C, Cunha FQ. Freitas A, et al. Among authors: nascimento dc. Shock. 2011 Jun;35(6):550-9. doi: 10.1097/SHK.0b013e31820e1ef0. Shock. 2011. PMID: 21330952
Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis.
Czaikoski PG, Nascimento DC, Sônego F, de Freitas A, Turato WM, de Carvalho MA, Santos RS, de Oliveira GP, dos Santos Samary C, Tefe-Silva C, Alves-Filho JC, Ferreira SH, Rossi MA, Rocco PR, Spiller F, Cunha FQ. Czaikoski PG, et al. Among authors: nascimento dc. Shock. 2013 Apr;39(4):389-96. doi: 10.1097/SHK.0b013e31828bbcf9. Shock. 2013. PMID: 23481491
Nitric oxide enhances Th9 cell differentiation and airway inflammation.
Niedbala W, Besnard AG, Nascimento DC, Donate PB, Sonego F, Yip E, Guabiraba R, Chang HD, Fukada SY, Salmond RJ, Schmitt E, Bopp T, Ryffel B, Liew FY. Niedbala W, et al. Among authors: nascimento dc. Nat Commun. 2014 Aug 7;5:4575. doi: 10.1038/ncomms5575. Nat Commun. 2014. PMID: 25099390 Free PMC article.
Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis.
Czaikoski PG, Mota JM, Nascimento DC, Sônego F, Castanheira FV, Melo PH, Scortegagna GT, Silva RL, Barroso-Sousa R, Souto FO, Pazin-Filho A, Figueiredo F, Alves-Filho JC, Cunha FQ. Czaikoski PG, et al. Among authors: nascimento dc. PLoS One. 2016 Feb 5;11(2):e0148142. doi: 10.1371/journal.pone.0148142. eCollection 2016. PLoS One. 2016. PMID: 26849138 Free PMC article.
SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology.
Veras FP, Pontelli MC, Silva CM, Toller-Kawahisa JE, de Lima M, Nascimento DC, Schneider AH, Caetité D, Tavares LA, Paiva IM, Rosales R, Colón D, Martins R, Castro IA, Almeida GM, Lopes MIF, Benatti MN, Bonjorno LP, Giannini MC, Luppino-Assad R, Almeida SL, Vilar F, Santana R, Bollela VR, Auxiliadora-Martins M, Borges M, Miranda CH, Pazin-Filho A, da Silva LLP, Cunha LD, Zamboni DS, Dal-Pizzol F, Leiria LO, Siyuan L, Batah S, Fabro A, Mauad T, Dolhnikoff M, Duarte-Neto A, Saldiva P, Cunha TM, Alves-Filho JC, Arruda E, Louzada-Junior P, Oliveira RD, Cunha FQ. Veras FP, et al. Among authors: nascimento dc. J Exp Med. 2020 Dec 7;217(12):e20201129. doi: 10.1084/jem.20201129. J Exp Med. 2020. PMID: 32926098 Free PMC article.
Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity.
Nascimento DC, Viacava PR, Ferreira RG, Damaceno MA, Piñeros AR, Melo PH, Donate PB, Toller-Kawahisa JE, Zoppi D, Veras FP, Peres RS, Menezes-Silva L, Caetité D, Oliveira AER, Castro ÍMS, Kauffenstein G, Nakaya HI, Borges MC, Zamboni DS, Fonseca DM, Paschoal JAR, Cunha TM, Quesniaux V, Linden J, Cunha FQ, Ryffel B, Alves-Filho JC. Nascimento DC, et al. Immunity. 2021 Sep 14;54(9):2024-2041.e8. doi: 10.1016/j.immuni.2021.08.005. Epub 2021 Sep 1. Immunity. 2021. PMID: 34473957 Free article.
Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology.
Silva CMS, Wanderley CWS, Veras FP, Gonçalves AV, Lima MHF, Toller-Kawahisa JE, Gomes GF, Nascimento DC, Monteiro VVS, Paiva IM, Almeida CJLR, Caetité DB, Silva JC, Lopes MIF, Bonjorno LP, Giannini MC, Amaral NB, Benatti MN, Santana RC, Damasceno LEA, Silva BMS, Schneider AH, Castro IMS, Silva JCS, Vasconcelos AP, Gonçalves TT, Batah SS, Rodrigues TS, Costa VF, Pontelli MC, Martins RB, Martins TV, Espósito DLA, Cebinelli GCM, da Fonseca BAL, Leiria LOS, Cunha LD, Arruda E, Nakaia HI, Fabro AT, Oliveira RDR, Zamboni DS, Louzada-Junior P, Cunha TM, Alves-Filho JCF, Cunha FQ. Silva CMS, et al. Among authors: nascimento dc. Crit Care. 2022 Jul 7;26(1):206. doi: 10.1186/s13054-022-04062-5. Crit Care. 2022. PMID: 35799268 Free PMC article.
The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils.
Toller-Kawahisa JE, Hiroki CH, Silva CMS, Nascimento DC, Públio GA, Martins TV, Damasceno LEA, Veras FP, Viacava PR, Sukesada FY, Day EA, Zotta A, Ryan TAJ, Moreira da Silva R, Cunha TM, Lopes NP, Cunha FQ, O'Neill LAJ, Alves-Filho JC. Toller-Kawahisa JE, et al. Among authors: nascimento dc. Nat Commun. 2023 Jul 17;14(1):4280. doi: 10.1038/s41467-023-40021-6. Nat Commun. 2023. PMID: 37460614 Free PMC article.
84 results