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AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Maiani E, Milletti G, Nazio F, Holdgaard SG, Bartkova J, Rizza S, Cianfanelli V, Lorente M, Simoneschi D, Di Marco M, D'Acunzo P, Di Leo L, Rasmussen R, Montagna C, Raciti M, De Stefanis C, Gabicagogeascoa E, Rona G, Salvador N, Pupo E, Merchut-Maya JM, Daniel CJ, Carinci M, Cesarini V, O'sullivan A, Jeong YT, Bordi M, Russo F, Campello S, Gallo A, Filomeni G, Lanzetti L, Sears RC, Hamerlik P, Bartolazzi A, Hynds RE, Pearce DR, Swanton C, Pagano M, Velasco G, Papaleo E, De Zio D, Maya-Mendoza A, Locatelli F, Bartek J, Cecconi F. Maiani E, et al. Among authors: nazio f. Nature. 2021 Apr;592(7856):799-803. doi: 10.1038/s41586-021-03422-5. Epub 2021 Apr 14. Nature. 2021. PMID: 33854232 Free PMC article.
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy.
Di Bartolomeo S, Corazzari M, Nazio F, Oliverio S, Lisi G, Antonioli M, Pagliarini V, Matteoni S, Fuoco C, Giunta L, D'Amelio M, Nardacci R, Romagnoli A, Piacentini M, Cecconi F, Fimia GM. Di Bartolomeo S, et al. Among authors: nazio f. J Cell Biol. 2010 Oct 4;191(1):155-68. doi: 10.1083/jcb.201002100. J Cell Biol. 2010. PMID: 20921139 Free PMC article.
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy.
Strappazzon F, Vietri-Rudan M, Campello S, Nazio F, Florenzano F, Fimia GM, Piacentini M, Levine B, Cecconi F. Strappazzon F, et al. Among authors: nazio f. EMBO J. 2011 Apr 6;30(7):1195-208. doi: 10.1038/emboj.2011.49. Epub 2011 Feb 25. EMBO J. 2011. PMID: 21358617 Free PMC article.
mTOR, AMBRA1, and autophagy: an intricate relationship.
Nazio F, Cecconi F. Nazio F, et al. Cell Cycle. 2013 Aug 15;12(16):2524-5. doi: 10.4161/cc.25835. Epub 2013 Jul 30. Cell Cycle. 2013. PMID: 23907135 Free PMC article. No abstract available.
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1.
Strappazzon F, Nazio F, Corrado M, Cianfanelli V, Romagnoli A, Fimia GM, Campello S, Nardacci R, Piacentini M, Campanella M, Cecconi F. Strappazzon F, et al. Among authors: nazio f. Cell Death Differ. 2015 Mar;22(3):419-32. doi: 10.1038/cdd.2014.139. Epub 2014 Sep 12. Cell Death Differ. 2015. PMID: 25215947 Free PMC article.
AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.
Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini PF, De Zio D, Nazio F, Antonioli M, D'Orazio M, Skobo T, Bordi M, Rohde M, Dalla Valle L, Helmer-Citterich M, Gretzmeier C, Dengjel J, Fimia GM, Piacentini M, Di Bartolomeo S, Velasco G, Cecconi F. Cianfanelli V, et al. Among authors: nazio f. Nat Cell Biol. 2015 Jan;17(1):20-30. doi: 10.1038/ncb3072. Epub 2014 Dec 1. Nat Cell Biol. 2015. PMID: 25438055 Free PMC article.
AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics.
Antonioli M, Albiero F, Nazio F, Vescovo T, Perdomo AB, Corazzari M, Marsella C, Piselli P, Gretzmeier C, Dengjel J, Cecconi F, Piacentini M, Fimia GM. Antonioli M, et al. Among authors: nazio f. Dev Cell. 2014 Dec 22;31(6):734-46. doi: 10.1016/j.devcel.2014.11.013. Epub 2014 Dec 11. Dev Cell. 2014. PMID: 25499913 Free article.
51 results