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Establishment and characterization of an iPSC line from a 35 years old high grade patient with nonalcoholic fatty liver disease (30-40% steatosis) with homozygous wildtype PNPLA3 genotype.
Graffmann N, Bohndorf M, Ncube A, Kawala MA, Wruck W, Kashofer K, Zatloukal K, Adjaye J. Graffmann N, et al. Among authors: ncube a. Stem Cell Res. 2018 Aug;31:113-116. doi: 10.1016/j.scr.2018.07.015. Epub 2018 Jul 25. Stem Cell Res. 2018. PMID: 30071394 Free article.
Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha.
Graffmann N, Ring S, Kawala MA, Wruck W, Ncube A, Trompeter HI, Adjaye J. Graffmann N, et al. Among authors: ncube a. Stem Cells Dev. 2016 Aug 1;25(15):1119-33. doi: 10.1089/scd.2015.0383. Epub 2016 Jul 15. Stem Cells Dev. 2016. PMID: 27308945 Free PMC article.
Derivation and characterization of integration-free iPSC line ISRM-UM51 derived from SIX2-positive renal cells isolated from urine of an African male expressing the CYP2D6 *4/*17 variant which confers intermediate drug metabolizing activity.
Bohndorf M, Ncube A, Spitzhorn LS, Enczmann J, Wruck W, Adjaye J. Bohndorf M, et al. Among authors: ncube a. Stem Cell Res. 2017 Dec;25:18-21. doi: 10.1016/j.scr.2017.10.004. Epub 2017 Oct 7. Stem Cell Res. 2017. PMID: 29035842 Free article.
30 results