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NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I.
Szklarczyk R, Wanschers BF, Nabuurs SB, Nouws J, Nijtmans LG, Huynen MA. Szklarczyk R, et al. FEBS Lett. 2011 Mar 9;585(5):737-43. doi: 10.1016/j.febslet.2011.01.046. Epub 2011 Feb 22. FEBS Lett. 2011. PMID: 21310150 Free article.
Based on the analysis of sequence conservation we propose intra-molecular disulfide bridges and the inter-membrane space localization of three Cx(9)C-containing subunits in human: NDUFS5, NDUFB7 and NDUFA8. We experimentally confirm the localization of the latter two, whil …
Based on the analysis of sequence conservation we propose intra-molecular disulfide bridges and the inter-membrane space localization of thr …
Protein N-myristoylation plays a critical role in the mitochondrial localization of human mitochondrial complex I accessory subunit NDUFB7.
Harada H, Moriya K, Kobuchi H, Ishihara N, Utsumi T. Harada H, et al. Sci Rep. 2023 Dec 27;13(1):22991. doi: 10.1038/s41598-023-50390-z. Sci Rep. 2023. PMID: 38151566 Free PMC article.
Furthermore, an analysis of the role of the CHCH domain in NDUFB7 using Cys to Ser mutants revealed that it was essential for the mitochondrial localization of NDUFB7. Therefore, the present results showed that NDUFB7, a vital component of human mitochondrial …
Furthermore, an analysis of the role of the CHCH domain in NDUFB7 using Cys to Ser mutants revealed that it was essential for the mit …
Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7.
Correia SP, Moedas MF, Naess K, Bruhn H, Maffezzini C, Calvo-Garrido J, Lesko N, Wibom R, Schober FA, Jemt A, Stranneheim H, Freyer C, Wedell A, Wredenberg A. Correia SP, et al. Hum Mutat. 2021 Apr;42(4):378-384. doi: 10.1002/humu.24173. Epub 2021 Feb 4. Hum Mutat. 2021. PMID: 33502047
Whole genome sequencing revealed an intronic biallelic mutation in the NDUFB7 gene (c.113-10C>G) and splicing pattern alterations in NDUFB7 messenger RNA were confirmed by RNA Sequencing. The detected variant resulted in a significant reduction of the NDUFB7
Whole genome sequencing revealed an intronic biallelic mutation in the NDUFB7 gene (c.113-10C>G) and splicing pattern alterations …
MicroRNA-2861 regulates the proliferation and apoptosis of human retinal vascular endothelial cells treated with high glucose by targeting NDUFB7.
Shi Q, Wang Q, Mao K, Liu Z, Wang R. Shi Q, et al. Heliyon. 2024 Aug 5;10(15):e35663. doi: 10.1016/j.heliyon.2024.e35663. eCollection 2024 Aug 15. Heliyon. 2024. PMID: 39170385 Free PMC article.
In addition, the upstream potential miRNAs of NDUFB7 were predicted online using the Targetscan website. RT-qPCR, Western blotting (WB), and dual luciferase gene reporter assay were used to confirm the targeting connection between miR-2861 and NDUFB7. ...CONCLUSIONS …
In addition, the upstream potential miRNAs of NDUFB7 were predicted online using the Targetscan website. RT-qPCR, Western blotting (W …
Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging.
Drekolia MK, Karantanou C, Wittig I, Li Y, Fuhrmann DC, Brüne B, Katsouda A, Hu J, Papapetropoulos A, Bibli SI. Drekolia MK, et al. Redox Biol. 2024 Feb;69:103014. doi: 10.1016/j.redox.2023.103014. Epub 2023 Dec 25. Redox Biol. 2024. PMID: 38171255 Free PMC article.
We further focused on one specific target, NDUFB7, which undergoes persulfidation by both CSE and 3MST derived sulfide species. In particular, persulfidation of cysteines C80 and C90 in NDUFB7 protects the protein from overoxidation and maintains the complex I activ …
We further focused on one specific target, NDUFB7, which undergoes persulfidation by both CSE and 3MST derived sulfide species. In pa …
Characterization of the human complex I NDUFB7 and 17.2-kDa cDNAs and mutational analysis of 19 genes of the HP fraction in complex I-deficient-patients.
Triepels R, Smeitink J, Loeffen J, Smeets R, Trijbels F, van den Heuvel L. Triepels R, et al. Hum Genet. 2000 Apr;106(4):385-91. doi: 10.1007/s004390000278. Hum Genet. 2000. PMID: 10830904
In order to complete our knowledge about the expected 36 structural nuclear complex I genes, we characterized the NDUFB7 and the 17.2-kDa cDNA sequences of the hydrophobic (HP) fraction of the complex. ...
In order to complete our knowledge about the expected 36 structural nuclear complex I genes, we characterized the NDUFB7 and the 17.2 …
Protein lysine acetylation played an important role in NH3-induced AEC2 damage and pulmonary fibrosis in piglets.
Wang X, Zhang D, Zhu Y, Li D, Shen L, Wang Q, Gao Y, Li X, Yu M. Wang X, et al. Sci Total Environ. 2024 Jan 15;908:168303. doi: 10.1016/j.scitotenv.2023.168303. Epub 2023 Nov 7. Sci Total Environ. 2024. PMID: 37939958
The expression or lysine acetylation levels of proteins involved in mitochondrial energy metabolism including fatty acid oxidation (CPT1A, ACADVL, ACADS, HADHA, and HADHB), TCA cycle (IDH2 and MDH2), and oxidative phosphorylation (NDUFB7, NDUFV1, ATP5PB, ATP5F1A, COX5A, an …
The expression or lysine acetylation levels of proteins involved in mitochondrial energy metabolism including fatty acid oxidation (CPT1A, A …
Quantitative proteomics identified 3 oxidative phosphorylation genes with clinical prognostic significance in gastric cancer.
Su F, Zhou FF, Zhang T, Wang DW, Zhao D, Hou XM, Feng MH. Su F, et al. J Cell Mol Med. 2020 Sep;24(18):10842-10854. doi: 10.1111/jcmm.15712. Epub 2020 Aug 5. J Cell Mol Med. 2020. PMID: 32757436 Free PMC article.
Furthermore the higher expression of UQCRQ, NDUFB7 and UQCRC2 were positively correlated with a better prognosis, implicating these proteins may as novel candidate diagnostic and prognostic biomarkers....
Furthermore the higher expression of UQCRQ, NDUFB7 and UQCRC2 were positively correlated with a better prognosis, implicating these p …
Changes in Mitochondria-Related Gene Expression upon Acupuncture at LR3 in the D-Galactosamine-Induced Liver Damage Rat Model.
Lee YM, Choi DH, Cheon MW, Kim JG, Kim JS, Shin MG, Kim HR, Youn D. Lee YM, et al. Evid Based Complement Alternat Med. 2022 Jun 29;2022:3294273. doi: 10.1155/2022/3294273. eCollection 2022. Evid Based Complement Alternat Med. 2022. PMID: 35928244 Free PMC article.
Of the 168 mitochondria-related genes profiled, two genes belonging to the solute-carrier transporter family (Slc25a15 and Slc25a25) and Ndufb7 were upregulated. Gamma-glutamylcysteine synthetase was more downregulated in MA than ALF. ...
Of the 168 mitochondria-related genes profiled, two genes belonging to the solute-carrier transporter family (Slc25a15 and Slc25a25) and …
Decrease in nicotinamide adenine dinucleotide dehydrogenase is related to skin pigmentation.
Nakama M, Murakami Y, Tanaka H, Nakata S. Nakama M, et al. J Cosmet Dermatol. 2012 Mar;11(1):3-8. doi: 10.1111/j.1473-2165.2011.00592.x. J Cosmet Dermatol. 2012. PMID: 22360328
In this study, we investigated this change and its effect on skin pigmentation using cultured human epidermal keratinocytes. The mRNA expression of NDUFA1, NDUFB7, and NDUFS2, subunits of NADH dehydrogenase, and its activity were significantly decreased in late passage ker …
In this study, we investigated this change and its effect on skin pigmentation using cultured human epidermal keratinocytes. The mRNA expres …
36 results