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NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I.
Szklarczyk R, Wanschers BF, Nabuurs SB, Nouws J, Nijtmans LG, Huynen MA. Szklarczyk R, et al. FEBS Lett. 2011 Mar 9;585(5):737-43. doi: 10.1016/j.febslet.2011.01.046. Epub 2011 Feb 22. FEBS Lett. 2011. PMID: 21310150 Free article.
Based on the analysis of sequence conservation we propose intra-molecular disulfide bridges and the inter-membrane space localization of three Cx(9)C-containing subunits in human: NDUFS5, NDUFB7 and NDUFA8. We experimentally confirm the localization of the latter two, whil …
Based on the analysis of sequence conservation we propose intra-molecular disulfide bridges and the inter-membrane space localization of thr …
Protein N-myristoylation plays a critical role in the mitochondrial localization of human mitochondrial complex I accessory subunit NDUFB7.
Harada H, Moriya K, Kobuchi H, Ishihara N, Utsumi T. Harada H, et al. Sci Rep. 2023 Dec 27;13(1):22991. doi: 10.1038/s41598-023-50390-z. Sci Rep. 2023. PMID: 38151566 Free PMC article.
Furthermore, an analysis of the role of the CHCH domain in NDUFB7 using Cys to Ser mutants revealed that it was essential for the mitochondrial localization of NDUFB7. Therefore, the present results showed that NDUFB7, a vital component of human mitochondrial …
Furthermore, an analysis of the role of the CHCH domain in NDUFB7 using Cys to Ser mutants revealed that it was essential for the mit …
Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7.
Correia SP, Moedas MF, Naess K, Bruhn H, Maffezzini C, Calvo-Garrido J, Lesko N, Wibom R, Schober FA, Jemt A, Stranneheim H, Freyer C, Wedell A, Wredenberg A. Correia SP, et al. Hum Mutat. 2021 Apr;42(4):378-384. doi: 10.1002/humu.24173. Epub 2021 Feb 4. Hum Mutat. 2021. PMID: 33502047
Whole genome sequencing revealed an intronic biallelic mutation in the NDUFB7 gene (c.113-10C>G) and splicing pattern alterations in NDUFB7 messenger RNA were confirmed by RNA Sequencing. The detected variant resulted in a significant reduction of the NDUFB7 …
Whole genome sequencing revealed an intronic biallelic mutation in the NDUFB7 gene (c.113-10C>G) and splicing pattern alterations …
Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging.
Drekolia MK, Karantanou C, Wittig I, Li Y, Fuhrmann DC, Brüne B, Katsouda A, Hu J, Papapetropoulos A, Bibli SI. Drekolia MK, et al. Redox Biol. 2024 Feb;69:103014. doi: 10.1016/j.redox.2023.103014. Epub 2023 Dec 25. Redox Biol. 2024. PMID: 38171255 Free PMC article.
Our findings revealed that cardiac persulfidated proteins in wild type hearts are less abundant compared to those in other organs, with a primary involvement in mitochondrial metabolic processes. We further focused on one specific target, NDUFB7, which undergoes persulfida …
Our findings revealed that cardiac persulfidated proteins in wild type hearts are less abundant compared to those in other organs, with a pr …
Characterization of the human complex I NDUFB7 and 17.2-kDa cDNAs and mutational analysis of 19 genes of the HP fraction in complex I-deficient-patients.
Triepels R, Smeitink J, Loeffen J, Smeets R, Trijbels F, van den Heuvel L. Triepels R, et al. Hum Genet. 2000 Apr;106(4):385-91. doi: 10.1007/s004390000278. Hum Genet. 2000. PMID: 10830904
In order to complete our knowledge about the expected 36 structural nuclear complex I genes, we characterized the NDUFB7 and the 17.2-kDa cDNA sequences of the hydrophobic (HP) fraction of the complex. ...
In order to complete our knowledge about the expected 36 structural nuclear complex I genes, we characterized the NDUFB7 and the 17.2 …
The Ubiquitin-Proteasome System Participates in Sperm Surface Subproteome Remodeling during Boar Sperm Capacitation.
Zigo M, Kerns K, Sutovsky P. Zigo M, et al. Biomolecules. 2023 Jun 15;13(6):996. doi: 10.3390/biom13060996. Biomolecules. 2023. PMID: 37371576 Free PMC article.

Abundances of 14 proteins were found to be significantly different (p < 0.05), exceeding a 1.5-fold abundance between the proteasomally inhibited (100 M MG132) and vehicle control (0.2% ethanol) groups. The proteins NIF3L1, CSE1L, NDUFB7, PGLS, PPP4C, STK39, and TPRG1L

…

Abundances of 14 proteins were found to be significantly different (p < 0.05), exceeding a 1.5-fold abundance between the proteasomally i

…
Association Between Mitochondrial Function and Rehabilitation of Parkinson's Disease: Revealed by Exosomal mRNA and lncRNA Expression Profiles.
Wang Y, Liu Y, Jin Z, Liu C, Yu X, Chen K, Meng D, Liu A, Fang B. Wang Y, et al. Front Aging Neurosci. 2022 Jun 16;14:909622. doi: 10.3389/fnagi.2022.909622. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35783124 Free PMC article.
Quantitative real-time polymerase chain reaction (qRT-PCR) validated that the expression levels of NDUFB7 mRNA and the 3 DElncRNAs increased significantly in pre-rehab PWPs, but decreased significantly in post-rehab PWPs compared to HCs. NDUFB7 mRNA is a marker rela …
Quantitative real-time polymerase chain reaction (qRT-PCR) validated that the expression levels of NDUFB7 mRNA and the 3 DElncRNAs in …
Quantitative proteomics identified 3 oxidative phosphorylation genes with clinical prognostic significance in gastric cancer.
Su F, Zhou FF, Zhang T, Wang DW, Zhao D, Hou XM, Feng MH. Su F, et al. J Cell Mol Med. 2020 Sep;24(18):10842-10854. doi: 10.1111/jcmm.15712. Epub 2020 Aug 5. J Cell Mol Med. 2020. PMID: 32757436 Free PMC article.
Moreover, GC possesses significantly altered biological metabolic processes, such as NADH dehydrogenase complex assembly and tricarboxylic acid cycle, which is mostly consistent with that in KEGG analysis. Furthermore the higher expression of UQCRQ, NDUFB7 and UQCRC2 were …
Moreover, GC possesses significantly altered biological metabolic processes, such as NADH dehydrogenase complex assembly and tricarboxylic a …
Changes in Mitochondria-Related Gene Expression upon Acupuncture at LR3 in the D-Galactosamine-Induced Liver Damage Rat Model.
Lee YM, Choi DH, Cheon MW, Kim JG, Kim JS, Shin MG, Kim HR, Youn D. Lee YM, et al. Evid Based Complement Alternat Med. 2022 Jun 29;2022:3294273. doi: 10.1155/2022/3294273. eCollection 2022. Evid Based Complement Alternat Med. 2022. PMID: 35928244 Free PMC article.
Of the 168 mitochondria-related genes profiled, two genes belonging to the solute-carrier transporter family (Slc25a15 and Slc25a25) and Ndufb7 were upregulated. Gamma-glutamylcysteine synthetase was more downregulated in MA than ALF. ...
Of the 168 mitochondria-related genes profiled, two genes belonging to the solute-carrier transporter family (Slc25a15 and Slc25a25) and …
Luteal Phase Ovarian Stimulation versus Follicular Phase Ovarian Stimulation results in different Human Cumulus cell genes expression: A pilot study.
Chen YC, Li JY, Li CJ, Tsui KH, Wang PH, Wen ZH, Lin LT. Chen YC, et al. Int J Med Sci. 2021 Feb 4;18(7):1600-1608. doi: 10.7150/ijms.55955. eCollection 2021. Int J Med Sci. 2021. PMID: 33746576 Free PMC article. Clinical Trial.
The levels of CC genes involved in inflammation (CXCL1, CXCL3, TNF, PTGES), oxidative phosphorylation (NDUFB7, NDUFA4L2, SLC25A27), apoptosis (DAPK3, BCL6B) and metabolism (PCK1, LDHC) were analyzed using real-time quantitative PCR and compared between the two groups. ...T …
The levels of CC genes involved in inflammation (CXCL1, CXCL3, TNF, PTGES), oxidative phosphorylation (NDUFB7, NDUFA4L2, SLC25A27), a …
34 results