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Rarity of human T helper 17 cells is due to retinoic acid orphan receptor-dependent mechanisms that limit their expansion.
Santarlasci V, Maggi L, Capone M, Querci V, Beltrame L, Cavalieri D, D'Aiuto E, Cimaz R, Nebbioso A, Liotta F, De Palma R, Maggi E, Cosmi L, Romagnani S, Annunziato F. Santarlasci V, et al. Among authors: nebbioso a. Immunity. 2012 Feb 24;36(2):201-14. doi: 10.1016/j.immuni.2011.12.013. Epub 2012 Feb 9. Immunity. 2012. PMID: 22326581 Free article.
Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring.
Guandalini L, Balliu M, Cellai C, Martino MV, Nebbioso A, Mercurio C, Carafa V, Bartolucci G, Dei S, Manetti D, Teodori E, Scapecchi S, Altucci L, Paoletti F, Romanelli MN. Guandalini L, et al. Among authors: nebbioso a. Eur J Med Chem. 2013 Aug;66:56-68. doi: 10.1016/j.ejmech.2013.05.017. Epub 2013 May 31. Eur J Med Chem. 2013. PMID: 23792316
Histone deacetylase inhibitors: a patent review (2009 - 2011).
Carafa V, Miceli M, Altucci L, Nebbioso A. Carafa V, et al. Among authors: nebbioso a. Expert Opin Ther Pat. 2013 Jan;23(1):1-17. doi: 10.1517/13543776.2013.736493. Epub 2012 Oct 25. Expert Opin Ther Pat. 2013. PMID: 23094822 Review.
Trials with 'epigenetic' drugs: an update.
Nebbioso A, Carafa V, Benedetti R, Altucci L. Nebbioso A, et al. Mol Oncol. 2012 Dec;6(6):657-82. doi: 10.1016/j.molonc.2012.09.004. Epub 2012 Oct 6. Mol Oncol. 2012. PMID: 23103179 Free PMC article. Review.
Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia.
Mai A, Jelicic K, Rotili D, Di Noia A, Alfani E, Valente S, Altucci L, Nebbioso A, Massa S, Galanello R, Brosch G, Migliaccio AR, Migliaccio G. Mai A, et al. Among authors: nebbioso a. Mol Pharmacol. 2007 Nov;72(5):1111-23. doi: 10.1124/mol.107.036772. Epub 2007 Jul 31. Mol Pharmacol. 2007. PMID: 17666592
148 results