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OXR1 maintains the retromer to delay brain aging under dietary restriction.
Wilson KA, Bar S, Dammer EB, Carrera EM, Hodge BA, Hilsabeck TAU, Bons J, Brownridge GW 3rd, Beck JN, Rose J, Granath-Panelo M, Nelson CS, Qi G, Gerencser AA, Lan J, Afenjar A, Chawla G, Brem RB, Campeau PM, Bellen HJ, Schilling B, Seyfried NT, Ellerby LM, Kapahi P. Wilson KA, et al. Among authors: nelson cs. Nat Commun. 2024 Jan 11;15(1):467. doi: 10.1038/s41467-023-44343-3. Nat Commun. 2024. PMID: 38212606 Free PMC article.
A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response.
Hilsabeck TAU, Liu-Bryan R, Guo T, Wilson KA, Bose N, Raftery D, Beck JN, Lang S, Jin K, Nelson CS, Oron T, Stoller M, Promislow D, Brem RB, Terkeltaub R, Kapahi P. Hilsabeck TAU, et al. Among authors: nelson cs. Geroscience. 2022 Aug;44(4):2195-2211. doi: 10.1007/s11357-022-00557-9. Epub 2022 Apr 6. Geroscience. 2022. PMID: 35381951 Free PMC article.
98 results