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The l-arginine/nitric oxide pathway is impaired in overweight/obese pregnant women.
Petrella E, Pignatti L, Neri I, Facchinetti F. Petrella E, et al. Pregnancy Hypertens. 2014 Apr;4(2):150-5. doi: 10.1016/j.preghy.2014.01.001. Epub 2014 Feb 3. Pregnancy Hypertens. 2014. PMID: 26104420 Free article.
STUDY DESIGN: Twelve women with BMI25 were compared with 10 normal-weight women in a fasting condition after the infusion of l-arginine (20g in 3h) and after the evaluation of the flow-mediated vasodilation (FMD) of the brachial artery between the 9th-12th and 24th-27th we …
STUDY DESIGN: Twelve women with BMI25 were compared with 10 normal-weight women in a fasting condition after the infusion of l-arginine ( …
L-arginine supplementation in patients with gestational hypertension: a pilot study.
Facchinetti F, Saade GR, Neri I, Pizzi C, Longo M, Volpe A. Facchinetti F, et al. Hypertens Pregnancy. 2007;26(1):121-30. doi: 10.1080/10641950601147994. Hypertens Pregnancy. 2007. PMID: 17454224 Clinical Trial.
METHODS: Patients with gestational hypertension and proteinuria (n = 28, >300 mg/24 h) and those without proteinuria (n = 46) were randomized in a double-blind design to receive either L-Arg (20g/500 mL intravenously daily, for 5 days followed by 4 g/day orally for 2 we …
METHODS: Patients with gestational hypertension and proteinuria (n = 28, >300 mg/24 h) and those without proteinuria (n = 46) were random …