Network connectivity predicts effectiveness of responsive neurostimulation in focal epilepsy.
Brain Commun. 2022.
PMID: 35611310
Free PMC article.
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network connectivity predict s effectiveness of responsive neurostimulation non focal epilepsy
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Towards network-guided neuromodulation for epilepsy.
Brain. 2022 Oct 21;145(10):3347-3362. doi: 10.1093/brain/awac234.
Brain. 2022.
PMID: 35771657
Free PMC article.
Review.
The convergence of these advancing fields is driving an era of 'network-guided neuromodulation' for epilepsy. In this review, we distil the current literature on network mechanisms underlying neurostimulation for epilepsy. ...We also report on i …
The convergence of these advancing fields is driving an era of 'network-guided neuromodulation' for epilepsy. In this review, …
Network connectivity predicts effectiveness of responsive neurostimulation in focal epilepsy.
Brain Commun. 2022 Apr 26;4(3):fcac104. doi: 10.1093/braincomms/fcac104. eCollection 2022.
Brain Commun. 2022.
PMID: 35611310
Free PMC article.
Responsive neurostimulation is a promising treatment for drug-resistant focal epilepsy; however, clinical outcomes are highly variable across individuals. The therapeutic mechanism of responsive neurostimulation likely involves modulatory …
Responsive neurostimulation is a promising treatment for drug-resistant focal epilepsy; however, clinical outcom …
Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy.
Sci Transl Med. 2021 Aug 25;13(608):eabf6588. doi: 10.1126/scitranslmed.abf6588.
Sci Transl Med. 2021.
PMID: 34433640
Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly deliver electrical stimulation to the brain, are effective in reducing seizures in some patients with focal epilepsy. ...The extent of this reorganization …
Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly deliver electrical stimulation to t …
Patient-specific structural connectivity informs outcomes of responsive neurostimulation for temporal lobe epilepsy.
Epilepsia. 2022 Aug;63(8):2037-2055. doi: 10.1111/epi.17298. Epub 2022 Jun 4.
Epilepsia. 2022.
PMID: 35560062
OBJECTIVE: Responsive neurostimulation is an effective therapy for patients with refractory mesial temporal lobe epilepsy. ...SIGNIFICANCE: Overall, our results suggest that the therapeutic effect of responsive neurostimulation may …
OBJECTIVE: Responsive neurostimulation is an effective therapy for patients with refractory mesial temporal lobe epi …
Intracranial electroencephalographic biomarker predicts effective responsive neurostimulation for epilepsy prior to treatment.
Epilepsia. 2022 Mar;63(3):652-662. doi: 10.1111/epi.17163. Epub 2022 Jan 7.
Epilepsia. 2022.
PMID: 34997577
Free PMC article.
OBJECTIVE: Despite the overall success of responsive neurostimulation (RNS) therapy for drug-resistant focal epilepsy, clinical outcomes in individuals vary significantly and are hard to predict. ...Our results suggest that network synchr …
OBJECTIVE: Despite the overall success of responsive neurostimulation (RNS) therapy for drug-resistant focal epileps …
Epileptogenic network of focal epilepsies mapped with cortico-cortical evoked potentials.
Clin Neurophysiol. 2020 Nov;131(11):2657-2666. doi: 10.1016/j.clinph.2020.08.012. Epub 2020 Sep 2.
Clin Neurophysiol. 2020.
PMID: 32957038
The root mean square of the amplitudes was calculated to reconstruct effective connectivity network. We also analyzed the N1/N2 amplitudes to explore the responsiveness influenced by epileptogenicity. ...Quantitative CCEPs can be useful in mapping epil …
The root mean square of the amplitudes was calculated to reconstruct effective connectivity network. We also analyzed t …
Prognostication of responsive neurostimulation system responsiveness using presurgical magnetoencephalography.
Brain Commun. 2022 May 9;4(3):fcac114. doi: 10.1093/braincomms/fcac114. eCollection 2022.
Brain Commun. 2022.
PMID: 35611311
Free PMC article.
This scientific commentary refers to 'Network connectivity predicts effectiveness of responsive neurostimulation in focal epilepsy', by Fan et al. ...
This scientific commentary refers to 'Network connectivity predicts effectiveness of responsive neuros …
Pre-implant modeling of depth lead placement in white matter for maximizing the extent of cortical activation during direct neurostimulation therapy.
Neurol Res. 2017 Mar;39(3):198-211. doi: 10.1080/01616412.2016.1266429. Epub 2017 Jan 12.
Neurol Res. 2017.
PMID: 28079471
INTRODUCTION: The objective of this work was to predict preoperatively the maximum extent to which direct stimulation therapy can propagate through an epileptic circuit for stabilizing refractory focal-onset epilepsy. ...CONCLUSION: This pre-implant modeling …
INTRODUCTION: The objective of this work was to predict preoperatively the maximum extent to which direct stimulation therapy can pro …
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