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Bayesian network analysis of panomic biological big data identifies the importance of triglyceride-rich LDL in atherosclerosis development.
Voros S, Bansal AT, Barnes MR, Narula J, Maurovich-Horvat P, Vazquez G, Marvasty IB, Brown BO, Voros ID, Harris W, Voros V, Dayspring T, Neff D, Greenfield A, Furchtgott L, Church B, Runge K, Khalil I, Hayete B, Lucero D, Remaley AT, Newton RS. Voros S, et al. Among authors: newton rs. Front Cardiovasc Med. 2023 Jan 4;9:960419. doi: 10.3389/fcvm.2022.960419. eCollection 2022. Front Cardiovasc Med. 2023. PMID: 36684605 Free PMC article.
Corrigendum to "Discovery of analogues of non-β oxidizable long-chain dicarboxylic fatty acids as dual inhibitors of fatty acids and cholesterol synthesis: Efficacy of lead compound in hyperlipidemic hamsters reveals novel mechanism" [Nutr Metabol Cardiovasc Dis 31 (2021) 2490-2703].
Srivastava RAK, Hurley TR, Oniciu D, Adeli K, Newton RS. Srivastava RAK, et al. Among authors: newton rs. Nutr Metab Cardiovasc Dis. 2022 Jan;32(1):290-293. doi: 10.1016/j.numecd.2021.10.002. Epub 2021 Dec 8. Nutr Metab Cardiovasc Dis. 2022. PMID: 34893416 No abstract available.
Discovery of analogues of non-β oxidizable long-chain dicarboxylic fatty acids as dual inhibitors of fatty acids and cholesterol synthesis: Efficacy of lead compound in hyperlipidemic hamsters reveals novel mechanism.
Srivastava RAK, Hurley TR, Oniciu D, Adeli K, Newton RS. Srivastava RAK, et al. Among authors: newton rs. Nutr Metab Cardiovasc Dis. 2021 Jul 22;31(8):2490-2506. doi: 10.1016/j.numecd.2021.05.024. Epub 2021 Jun 1. Nutr Metab Cardiovasc Dis. 2021. PMID: 34172319
Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR+/- and LDLR-/-) Yucatan Miniature Pigs.
Burke AC, Telford DE, Sutherland BG, Edwards JY, Sawyez CG, Barrett PHR, Newton RS, Pickering JG, Huff MW. Burke AC, et al. Among authors: newton rs. Arterioscler Thromb Vasc Biol. 2018 May;38(5):1178-1190. doi: 10.1161/ATVBAHA.117.310676. Epub 2018 Feb 15. Arterioscler Thromb Vasc Biol. 2018. PMID: 29449335 Free article.
Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr-/- Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid.
Samsoondar JP, Burke AC, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Pinkosky SL, Newton RS, Huff MW. Samsoondar JP, et al. Among authors: newton rs. Arterioscler Thromb Vasc Biol. 2017 Apr;37(4):647-656. doi: 10.1161/ATVBAHA.116.308963. Epub 2017 Feb 2. Arterioscler Thromb Vasc Biol. 2017. PMID: 28153881
Treatment with ETC-1002 alone and in combination with ezetimibe lowers LDL cholesterol in hypercholesterolemic patients with or without statin intolerance.
Thompson PD, MacDougall DE, Newton RS, Margulies JR, Hanselman JC, Orloff DG, McKenney JM, Ballantyne CM. Thompson PD, et al. Among authors: newton rs. J Clin Lipidol. 2016 May-Jun;10(3):556-67. doi: 10.1016/j.jacl.2015.12.025. Epub 2016 Jan 6. J Clin Lipidol. 2016. PMID: 27206943 Free article. Clinical Trial.
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