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Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis.
Tsuchiya Y, Seki T, Kobayashi K, Komazawa-Sakon S, Shichino S, Nishina T, Fukuhara K, Ikejima K, Nagai H, Igarashi Y, Ueha S, Oikawa A, Tsurusaki S, Yamazaki S, Nishiyama C, Mikami T, Yagita H, Okumura K, Kido T, Miyajima A, Matsushima K, Imasaka M, Araki K, Imamura T, Ohmuraya M, Tanaka M, Nakano H. Tsuchiya Y, et al. Among authors: nishina t. Nat Commun. 2023 Oct 9;14(1):6304. doi: 10.1038/s41467-023-42058-z. Nat Commun. 2023. PMID: 37813881 Free PMC article.
Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer.
Nishina T, Deguchi Y, Ohshima D, Takeda W, Ohtsuka M, Shichino S, Ueha S, Yamazaki S, Kawauchi M, Nakamura E, Nishiyama C, Kojima Y, Adachi-Akahane S, Hasegawa M, Nakayama M, Oshima M, Yagita H, Shibuya K, Mikami T, Inohara N, Matsushima K, Tada N, Nakano H. Nishina T, et al. Nat Commun. 2021 Apr 16;12(1):2281. doi: 10.1038/s41467-021-22450-3. Nat Commun. 2021. PMID: 33863879 Free PMC article.
IκBζ controls IL-17-triggered gene expression program in intestinal epithelial cells that restricts colonization of SFB and prevents Th17-associated pathologies.
Yamazaki S, Inohara N, Ohmuraya M, Tsuneoka Y, Yagita H, Katagiri T, Nishina T, Mikami T, Funato H, Araki K, Nakano H. Yamazaki S, et al. Among authors: nishina t. Mucosal Immunol. 2022 Jun;15(6):1321-1337. doi: 10.1038/s41385-022-00554-3. Epub 2022 Aug 24. Mucosal Immunol. 2022. PMID: 35999460 Free PMC article.
Importin β1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells.
Kojima Y, Nakayama M, Nishina T, Nakano H, Koyanagi M, Takeda K, Okumura K, Yagita H. Kojima Y, et al. Among authors: nishina t. J Biol Chem. 2011 Dec 16;286(50):43383-93. doi: 10.1074/jbc.M111.309377. Epub 2011 Oct 21. J Biol Chem. 2011. PMID: 22020938 Free PMC article.
Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis.
Shindo R, Ohmuraya M, Komazawa-Sakon S, Miyake S, Deguchi Y, Yamazaki S, Nishina T, Yoshimoto T, Kakuta S, Koike M, Uchiyama Y, Konishi H, Kiyama H, Mikami T, Moriwaki K, Araki K, Nakano H. Shindo R, et al. Among authors: nishina t. iScience. 2019 May 31;15:536-551. doi: 10.1016/j.isci.2019.05.011. Epub 2019 May 14. iScience. 2019. PMID: 31132747 Free PMC article.
Regenerating islet-derived protein (Reg)3β plays a crucial role in attenuation of ileitis and colitis in mice.
Shindo R, Katagiri T, Komazawa-Sakon S, Ohmuraya M, Takeda W, Nakagawa Y, Nakagata N, Sakuma T, Yamamoto T, Nishiyama C, Nishina T, Yamazaki S, Kameda H, Nakano H. Shindo R, et al. Among authors: nishina t. Biochem Biophys Rep. 2020 Feb 7;21:100738. doi: 10.1016/j.bbrep.2020.100738. eCollection 2020 Mar. Biochem Biophys Rep. 2020. PMID: 32072024 Free PMC article.
c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
Piao X, Komazawa-Sakon S, Nishina T, Koike M, Piao JH, Ehlken H, Kurihara H, Hara M, Van Rooijen N, Schütz G, Ohmuraya M, Uchiyama Y, Yagita H, Okumura K, He YW, Nakano H. Piao X, et al. Among authors: nishina t. Sci Signal. 2012 Dec 18;5(255):ra93. doi: 10.1126/scisignal.2003558. Sci Signal. 2012. PMID: 23250397 Free PMC article.
420 results