Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2017 1
2019 2
2020 1
2021 1
2022 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

4 results

Results by year

Citations

1 article found by citation matching

Search results

Filters applied: . Clear all
Page 1
No effect of topical application of tranexamic acid on articular cartilage.
Ambra LF, de Girolamo L, Niu W, Phan A, Spector M, Gomoll AH. Ambra LF, et al. Knee Surg Sports Traumatol Arthrosc. 2019 Mar;27(3):931-935. doi: 10.1007/s00167-017-4746-9. Epub 2017 Nov 8. Knee Surg Sports Traumatol Arthrosc. 2019. PMID: 29119286
PURPOSE: The objective of this study was to evaluate potential cytotoxicity of TXA on articular cartilage by assessing chondrocyte viability of osteochondral explants after exposure to different concentrations and durations of TXA. ...Thus, supporting the topical …
PURPOSE: The objective of this study was to evaluate potential cytotoxicity of TXA on articular cartilage by assessing chondro …
Toxicity of tranexamic acid (TXA) to intra-articular tissue in orthopaedic surgery: a scoping review.
Bolam SM, O'Regan-Brown A, Paul Monk A, Musson DS, Cornish J, Munro JT. Bolam SM, et al. Knee Surg Sports Traumatol Arthrosc. 2021 Jun;29(6):1862-1871. doi: 10.1007/s00167-020-06219-7. Epub 2020 Aug 29. Knee Surg Sports Traumatol Arthrosc. 2021. PMID: 32860523 Review.
PURPOSE: Intra-articular administration of tranexamic acid (TXA) in orthopaedic arthroplasty and arthroscopic procedures has become increasingly common over the past decade. However, several recent reports have shown that TXA has the potential to be cytotoxic …
PURPOSE: Intra-articular administration of tranexamic acid (TXA) in orthopaedic arthroplasty and arthroscopic procedure …
Cytotoxicity of tranexamic acid to tendon and bone in vitro: Is there a safe dosage?
Bolam SM, O'Regan-Brown A, Konar S, Callon KE, Coleman B, Dalbeth N, Monk AP, Musson DS, Cornish J, Munro JT. Bolam SM, et al. J Orthop Surg Res. 2022 May 15;17(1):273. doi: 10.1186/s13018-022-03167-5. J Orthop Surg Res. 2022. PMID: 35570313 Free PMC article.
INTRODUCTION: Tranexamic acid (TXA) has been shown to be effective at reducing peri-operative blood loss and haemarthrosis in arthroplasty and arthroscopic soft tissue reconstructions. Intra-articular application, as an injection or peri-arti …
INTRODUCTION: Tranexamic acid (TXA) has been shown to be effective at reducing peri-operative blood loss and haemarthro …
Short exposure to tranexamic acid does not affect, in vitro, the viability of human chondrocytes.
Goderecci R, Giusti I, Necozione S, Cinque B, D'Ascenzo S, Dolo V, Calvisi V. Goderecci R, et al. Eur J Med Res. 2019 Feb 22;24(1):15. doi: 10.1186/s40001-019-0373-x. Eur J Med Res. 2019. PMID: 30795796 Free PMC article.
BACKGROUND: Only few studies have investigated the effect of topical application of tranexamic acid (TXA) on "minimally" invasive joint surgical procedures in which articular cartilage is preserved; for this reason, actually many s …
BACKGROUND: Only few studies have investigated the effect of topical application of tranexamic acid (TXA) …