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Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients.
Finkelstein SE, Iclozan C, Bui MM, Cotter MJ, Ramakrishnan R, Ahmed J, Noyes DR, Cheong D, Gonzalez RJ, Heysek RV, Berman C, Lenox BC, Janssen W, Zager JS, Sondak VK, Letson GD, Antonia SJ, Gabrilovich DI. Finkelstein SE, et al. Among authors: noyes dr. Int J Radiat Oncol Biol Phys. 2012 Feb 1;82(2):924-32. doi: 10.1016/j.ijrobp.2010.12.068. Epub 2011 Mar 11. Int J Radiat Oncol Biol Phys. 2012. PMID: 21398051 Free PMC article. Clinical Trial.
A phase-I trial using a universal GM-CSF-producing and CD40L-expressing bystander cell line (GM.CD40L) in the formulation of autologous tumor cell-based vaccines for cancer patients with stage IV disease.
Dessureault S, Noyes D, Lee D, Dunn M, Janssen W, Cantor A, Sotomayor E, Messina J, Antonia SJ. Dessureault S, et al. Ann Surg Oncol. 2007 Feb;14(2):869-84. doi: 10.1245/s10434-006-9196-4. Epub 2006 Nov 14. Ann Surg Oncol. 2007. PMID: 17103257 Clinical Trial.
Phase II trial of B7-1 (CD-86) transduced, cultured autologous tumor cell vaccine plus subcutaneous interleukin-2 for treatment of stage IV renal cell carcinoma.
Fishman M, Hunter TB, Soliman H, Thompson P, Dunn M, Smilee R, Farmelo MJ, Noyes DR, Mahany JJ, Lee JH, Cantor A, Messina J, Seigne J, Pow-Sang J, Janssen W, Antonia SJ. Fishman M, et al. Among authors: noyes dr. J Immunother. 2008 Jan;31(1):72-80. doi: 10.1097/CJI.0b013e31815ba792. J Immunother. 2008. PMID: 18157014 Clinical Trial.
A GM-CSF/CD40L producing cell augments anti-tumor T cell responses.
Dessureault S, Alsarraj M, McCarthy S, Hunter T, Noyes D, Lee D, Harkins J, Seigne J, Jennings R, Antonia SJ. Dessureault S, et al. J Surg Res. 2005 May 15;125(2):173-81. doi: 10.1016/j.jss.2004.11.036. Epub 2005 Jan 28. J Surg Res. 2005. PMID: 15854671
HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma.
Zheng H, Zhao W, Yan C, Watson CC, Massengill M, Xie M, Massengill C, Noyes DR, Martinez GV, Afzal R, Chen Z, Ren X, Antonia SJ, Haura EB, Ruffell B, Beg AA. Zheng H, et al. Among authors: noyes dr. Clin Cancer Res. 2016 Aug 15;22(16):4119-32. doi: 10.1158/1078-0432.CCR-15-2584. Epub 2016 Mar 10. Clin Cancer Res. 2016. PMID: 26964571 Free PMC article.
21 results