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Year Number of Results
2005 1
2007 1
2008 1
2009 2
2010 4
2011 4
2012 4
2013 3
2014 1
2015 7
2016 7
2017 10
2018 10
2019 5
2020 11
2021 7
2022 14
2023 11
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95 results

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Page 1
The emerging role of NPNT in tissue injury repair and bone homeostasis.
Sun Y, Kuek V, Qiu H, Tickner J, Chen L, Wang H, He W, Xu J. Sun Y, et al. J Cell Physiol. 2018 Mar;233(3):1887-1894. doi: 10.1002/jcp.26013. Epub 2017 Jun 16. J Cell Physiol. 2018. PMID: 28513838 Review.
Moreover, NPNT regulates osteoblast differentiation and mineralization, as well as osteogenic angiogenesis. ...Further understanding the cellular and molecular mechanisms by which NPNT regulates tissue homeostasis in an organ-specific manner is critical in exploring …
Moreover, NPNT regulates osteoblast differentiation and mineralization, as well as osteogenic angiogenesis. ...Further understanding …
A null founder variant in NPNT, encoding nephronectin, causes autosomal recessive renal agenesis.
Al-Hamed MH, Altuwaijri N, Alsahan N, Ali W, Abdulwahab F, Alzahrani F, Majrashi N, Alkuraya FS. Al-Hamed MH, et al. Clin Genet. 2022 Jul;102(1):61-65. doi: 10.1111/cge.14128. Epub 2022 Mar 22. Clin Genet. 2022. PMID: 35246978
Exome sequencing detected a nonsense variant in NPNT in both families within the linkage interval. The pathogenicity of this variant was supported by reverse transcription polymerase chain reaction data showing complete nonsense-mediated decay of the NPNT transcript …
Exome sequencing detected a nonsense variant in NPNT in both families within the linkage interval. The pathogenicity of this variant …
[Recent advances in nephronectin].
Qian GQ, Yang NB, Shi JJ. Qian GQ, et al. Sheng Li Xue Bao. 2019 Oct 25;71(5):799-805. Sheng Li Xue Bao. 2019. PMID: 31646334 Free article. Review. Chinese.
Nephronectin (NPNT) is a novel extracellular matrix protein and a new ligand of integrin alpha8beta1. ...NPNT may play a key role in pathological osteoporosis and therefore be a new therapeutic target of bone diseases. ...
Nephronectin (NPNT) is a novel extracellular matrix protein and a new ligand of integrin alpha8beta1. ...NPNT may play a key r …
Integrated analysis identified NPNT as a potential key regulator in tumor metastasis of hepatocellular carcinoma.
Huang L, Guan S, Feng L, Wei J, Wu L. Huang L, et al. Gene. 2022 May 30;825:146436. doi: 10.1016/j.gene.2022.146436. Epub 2022 Mar 15. Gene. 2022. PMID: 35304239
We found that NPNT was up-regulated in HCC tumor tissues compared with normal tissues. ...Our results demonstrate that NPNT is a potential key regulator in HCC metastasis....
We found that NPNT was up-regulated in HCC tumor tissues compared with normal tissues. ...Our results demonstrate that NPNT is …
Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity.
Yoshiji S, Butler-Laporte G, Lu T, Willett JDS, Su CY, Nakanishi T, Morrison DR, Chen Y, Liang K, Hultström M, Ilboudo Y, Afrasiabi Z, Lan S, Duggan N, DeLuca C, Vaezi M, Tselios C, Xue X, Bouab M, Shi F, Laurent L, Münter HM, Afilalo M, Afilalo J, Mooser V, Timpson NJ, Zeberg H, Zhou S, Forgetta V, Farjoun Y, Richards JB. Yoshiji S, et al. Nat Metab. 2023 Feb;5(2):248-264. doi: 10.1038/s42255-023-00742-w. Epub 2023 Feb 20. Nat Metab. 2023. PMID: 36805566 Free PMC article.
The effect was driven by an NPNT splice isoform. Mediation analyses supported NPNT as a mediator. In single-cell RNA-sequencing, NPNT was expressed in alveolar cells and fibroblasts of the lung in individuals who died of COVID-19. ...
The effect was driven by an NPNT splice isoform. Mediation analyses supported NPNT as a mediator. In single-cell RNA-sequencin …
NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase.
Kuek V, Yang Z, Chim SM, Zhu S, Xu H, Chow ST, Tickner J, Rosen V, Erber W, Li X, Qin A, Qian Y, Xu J. Kuek V, et al. Sci Rep. 2016 Oct 26;6:36210. doi: 10.1038/srep36210. Sci Rep. 2016. PMID: 27782206 Free PMC article.
In addition, the protein levels of NPNT and CD31 are also found to be reduced in the tibias of OVX mice. ...Furthermore, NPNT promotes angiogenesis in an ex vivo fetal mouse metatarsal angiogenesis assay. ...
In addition, the protein levels of NPNT and CD31 are also found to be reduced in the tibias of OVX mice. ...Furthermore, NPNT …
Nephronectin (NPNT) and the prediction of nephrotic syndrome response to steroid treatment.
Watany MM, El-Horany HE. Watany MM, et al. Eur J Hum Genet. 2018 Sep;26(9):1354-1360. doi: 10.1038/s41431-018-0182-7. Epub 2018 Jun 11. Eur J Hum Genet. 2018. PMID: 29891875 Free PMC article.
Regression analysis showed that both NPNT expression and NPNT serum level can be independent predictors of steroid resistance. The present study shows for the first time an enhanced expression of NPNT in steroid-sensitive nephrotic syndrome patients suggestin …
Regression analysis showed that both NPNT expression and NPNT serum level can be independent predictors of steroid resistance. …
NPNT promotes early-stage bone metastases in breast cancer by regulation of the osteogenic niche.
Wang D, Zhao C, Gao L, Wang Y, Gao X, Tang L, Zhang K, Li Z, Han J, Xiao J. Wang D, et al. J Bone Oncol. 2018 Sep 27;13:91-96. doi: 10.1016/j.jbo.2018.09.006. eCollection 2018 Nov. J Bone Oncol. 2018. PMID: 30591862 Free PMC article.
But the role of NPNT in mediating breast cancer bone metastases remains elusive. In the present study, we revealed that up regulation of NPNT is associated with incidence of bone metastases. What's more, NPNT could significantly enhance the tumor cell clone f …
But the role of NPNT in mediating breast cancer bone metastases remains elusive. In the present study, we revealed that up regulation …
Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis.
Müller-Deile J, Sopel N, Ohs A, Rose V, Gröner M, Wrede C, Hegermann J, Daniel C, Amann K, Zahner G, Schiffer M. Müller-Deile J, et al. J Am Soc Nephrol. 2021 Nov;32(11):2777-2794. doi: 10.1681/ASN.2020121699. J Am Soc Nephrol. 2021. PMID: 34716242 Free PMC article.
IgG-size nanoparticles accumulated in lucidity areas of the lamina rara interna and lamina densa of the GBM in npnt-knockdown zebrafish models. Loss of slit diaphragm proteins and severe structural impairment of the GBM were further confirmed in podocyte-specific Npnt …
IgG-size nanoparticles accumulated in lucidity areas of the lamina rara interna and lamina densa of the GBM in npnt-knockdown zebrafi …
95 results