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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 6
1995 5
1996 3
1997 4
1998 4
1999 5
2000 9
2001 8
2002 6
2003 4
2004 6
2005 14
2006 9
2007 6
2008 14
2009 19
2010 17
2011 18
2012 23
2013 25
2014 33
2015 34
2016 69
2017 81
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2023 120
2024 67

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1,158 results

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Page 1
NTRK1 Congenital Insensitivity to Pain with Anhidrosis.
Indo Y. Indo Y. 2008 Aug 5 [updated 2020 Apr 30]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2008 Aug 5 [updated 2020 Apr 30]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301726 Free Books & Documents. Review.
CLINICAL CHARACTERISTICS: NTRK1 congenital insensitivity to pain with anhidrosis (NTRK1-CIPA) is characterized by insensitivity to pain, anhidrosis (the inability to sweat), and intellectual disability. ...GENETIC COUNSELING: NTRK1-CIPA results from the prese …
CLINICAL CHARACTERISTICS: NTRK1 congenital insensitivity to pain with anhidrosis (NTRK1-CIPA) is characterized by insensitivit …
NTRK1/TrkA Activation Overrides the G(2)/M-Checkpoint upon Irradiation.
Hassiepen C, Soni A, Rudolf I, Boron V, Oeck S, Iliakis G, Schramm A. Hassiepen C, et al. Cancers (Basel). 2021 Nov 30;13(23):6023. doi: 10.3390/cancers13236023. Cancers (Basel). 2021. PMID: 34885133 Free PMC article.
Here, we used human neuroblastoma cell lines with inducible TrkA/NTRK1 expression to mechanistically explore the role of TrkA/NTRK1 signaling in checkpoint activation after DNA damage induced by ionizing radiation (IR). TrkA/NTRK1 activated cells showed incre …
Here, we used human neuroblastoma cell lines with inducible TrkA/NTRK1 expression to mechanistically explore the role of TrkA/NTRK …
NTRK1 knockdown induces mouse cognitive impairment and hippocampal neuronal damage through mitophagy suppression via inactivating the AMPK/ULK1/FUNDC1 pathway.
Yang K, Wu J, Li S, Wang S, Zhang J, Wang YP, Yan YS, Hu HY, Xiong MF, Bai CB, Sun YQ, Chen WQ, Zeng Y, Yuan JL, Yin CH. Yang K, et al. Cell Death Discov. 2023 Oct 31;9(1):404. doi: 10.1038/s41420-023-01685-7. Cell Death Discov. 2023. PMID: 37907480 Free PMC article.
The present study aimed to investigate the role of NTRK1 in mouse hippocampal neuronal damage and the specific mechanism. ...Subsequently, rescue experiments were performed by subjecting the NTRK1-knockdown neurons to pre-treatment with O304 and Rapamycin. ...
The present study aimed to investigate the role of NTRK1 in mouse hippocampal neuronal damage and the specific mechanism. ...Subseque …
NTRK1 Spitz melanoma presenting clinically as an angioma.
Arasheben A, Desai M, Lee MP, Love J, Chow C, Kerstetter J, Elsensohn A. Arasheben A, et al. Int J Dermatol. 2023 Sep;62(9):e488-e489. doi: 10.1111/ijd.16610. Epub 2023 Feb 1. Int J Dermatol. 2023. PMID: 36726044 No abstract available.
[A NTRK1-rearranged mammary carcinoma].
Remoué A, Conan-Charlet V, Le Flahec G, Lambros L, Marcorelles P, Uguen A. Remoué A, et al. Ann Pathol. 2020 Jan;40(1):42-45. doi: 10.1016/j.annpat.2019.05.009. Epub 2019 Jun 26. Ann Pathol. 2020. PMID: 31253456 French. No abstract available.
NTRK1 is a positive regulator of YAP oncogenic function.
Yang X, Shen H, Buckley B, Chen Y, Yang N, Mussell AL, Chernov M, Kobzik L, Frangou C, Han SX, Zhang J. Yang X, et al. Oncogene. 2019 Apr;38(15):2778-2787. doi: 10.1038/s41388-018-0609-1. Epub 2018 Dec 12. Oncogene. 2019. PMID: 30542115 Free PMC article.
NTRK1 inhibition decreased YAP-driven transcription, cancer cell proliferation and migration. ...Taken together, these results provide compelling evidence of crosstalks between the NGF-NTRK1 and Hippo cancer pathways....
NTRK1 inhibition decreased YAP-driven transcription, cancer cell proliferation and migration. ...Taken together, these results provid …
Rearrangements of NTRK1 gene in papillary thyroid carcinoma.
Greco A, Miranda C, Pierotti MA. Greco A, et al. Mol Cell Endocrinol. 2010 May 28;321(1):44-9. doi: 10.1016/j.mce.2009.10.009. Epub 2009 Oct 31. Mol Cell Endocrinol. 2010. PMID: 19883730 Review.
TRK oncogenes are observed in a consistent fraction of papillary thyroid carcinoma (PTC); they arise from the fusion of the 3' terminal sequences of the NTRK1/NGF receptor gene with 5' terminal sequences of various activating genes, such as TPM3, TPR and TFG. ...The follow …
TRK oncogenes are observed in a consistent fraction of papillary thyroid carcinoma (PTC); they arise from the fusion of the 3' terminal sequ …
NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells.
Zhang C, Jiao B, Cao X, Zhang W, Yu S, Zhang K, Zhang M, Zhang X. Zhang C, et al. Biomed Pharmacother. 2023 Dec 31;169:115889. doi: 10.1016/j.biopha.2023.115889. Epub 2023 Nov 18. Biomed Pharmacother. 2023. PMID: 37984302 Free article.
Despite this knowledge, the precise mechanisms through which NTRK1 and IGF2 influence cell responses to Mn-induced neuronal damage remain elusive. ...Real-time Quantitative PCR (qPCR) determined gene expression levels, while Western blotting measured protein expression. RE …
Despite this knowledge, the precise mechanisms through which NTRK1 and IGF2 influence cell responses to Mn-induced neuronal damage re …
Oncogenic rearrangements of the NTRK1/NGF receptor.
Pierotti MA, Greco A. Pierotti MA, et al. Cancer Lett. 2006 Jan 28;232(1):90-8. doi: 10.1016/j.canlet.2005.07.043. Epub 2005 Oct 20. Cancer Lett. 2006. PMID: 16242838 Review.
The NTRK1 gene encodes the high affinity receptor for Nerve Growth Factor, and its action regulates neural development and differentiation. ...Constitutive activation of NTRK1 has been detected in several tumor types. An autocrine loop involving NTRK1 and NGF …
The NTRK1 gene encodes the high affinity receptor for Nerve Growth Factor, and its action regulates neural development and differenti …
1,158 results