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1975 2
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1981 1
1982 1
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1985 2
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1991 3
1992 1
1993 3
1995 1
1996 1
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1998 3
1999 3
2000 2
2001 4
2002 3
2003 4
2004 4
2005 5
2006 8
2007 6
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2012 3
2013 3
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2023 3
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153 results

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Page 1
Biofunctional Effects of Thiohemiaminal-Type Dimeric Sesquiterpene Alkaloids from Nuphar Plants.
Matsuda H, Nakamura S, Nakashima S, Fukaya M, Yoshikawa M. Matsuda H, et al. Chem Pharm Bull (Tokyo). 2019;67(7):666-674. doi: 10.1248/cpb.c18-01030. Chem Pharm Bull (Tokyo). 2019. PMID: 31257322 Free article. Review.
Dimeric sesquiterpene thioalkaloids from the rhizomes of Nuphar pumilum exhibited immunosuppressive effects using a sheep erythrocyte plaque forming cell (PFC) assay, as well as an anti-metastasis effect, and rapid apoptosis-inducing effects in tumor cell lines. ...
Dimeric sesquiterpene thioalkaloids from the rhizomes of Nuphar pumilum exhibited immunosuppressive effects using a sheep erythrocyte …
Nuphar lutea Extracts Exhibit Anti-Viral Activity against the Measles Virus.
Winer H, Ozer J, Shemer Y, Reichenstein I, Eilam-Frenkel B, Benharroch D, Golan-Goldhirsh A, Gopas J. Winer H, et al. Molecules. 2020 Apr 3;25(7):1657. doi: 10.3390/molecules25071657. Molecules. 2020. PMID: 32260270 Free PMC article.
Different parts of Nuphar lutea L. (yellow water lily) have been used to treat several inflammatory and pathogen-related diseases. It has shown that Nuphar lutea extracts (NUP) are active against various pathogens including bacteria, fungi, and leishmanial parasites …
Different parts of Nuphar lutea L. (yellow water lily) have been used to treat several inflammatory and pathogen-related diseases. It …
Nuphar alkaloids induce very rapid apoptosis through a novel caspase-dependent but BAX/BAK-independent pathway.
Mallick DJ, Korotkov A, Li H, Wu J, Eastman A. Mallick DJ, et al. Cell Biol Toxicol. 2019 Oct;35(5):435-443. doi: 10.1007/s10565-019-09469-5. Epub 2019 Mar 2. Cell Biol Toxicol. 2019. PMID: 30826899 Free PMC article.
Nuphar alkaloids, originally isolated from water lilies, induce apoptosis in mammalian cells in less than 1 h, making them possibly the fastest known inducers. ...These results suggest a novel mechanism of apoptosis that has previously not been reported. The molecular targ …
Nuphar alkaloids, originally isolated from water lilies, induce apoptosis in mammalian cells in less than 1 h, making them possibly t …
Nuphar Dimers: Crouching Sulfur, Hidden Reactivity.
Marcaurelle LA, Mulvihill MJ. Marcaurelle LA, et al. ACS Cent Sci. 2016 Jun 22;2(6):367-9. doi: 10.1021/acscentsci.6b00166. Epub 2016 Jun 14. ACS Cent Sci. 2016. PMID: 27413779 Free PMC article. No abstract available.
Total Synthesis of Unsymmetrically Oxidized Nuphar Thioalkaloids via Copper-Catalyzed Thiolane Assembly.
Lacharity JJ, Fournier J, Lu P, Mailyan AK, Herrmann AT, Zakarian A. Lacharity JJ, et al. J Am Chem Soc. 2017 Sep 27;139(38):13272-13275. doi: 10.1021/jacs.7b07685. Epub 2017 Sep 19. J Am Chem Soc. 2017. PMID: 28911224 Free PMC article.
An asymmetric total synthesis of (+)-6-hydroxythiobinupharidine (1b) and (-)-6-hydroxythionuphlutine (2b), a set of hemiaminal containing dimeric sesquiterpenes isolated from yellow water lilies of the Nuphar genus, is described. The central bis-spirocyclic tetrahydrothiop …
An asymmetric total synthesis of (+)-6-hydroxythiobinupharidine (1b) and (-)-6-hydroxythionuphlutine (2b), a set of hemiaminal containing di …
Cytotoxicity of Thioalkaloid-Enriched Nuphar lutea Extract and Purified 6,6'-Dihydroxythiobinupharidine in Acute Myeloid Leukemia Cells: The Role of Oxidative Stress and Intracellular Calcium.
Muduli S, Golan-Goldhirsh A, Gopas J, Danilenko M. Muduli S, et al. Pharmaceuticals (Basel). 2022 Mar 28;15(4):410. doi: 10.3390/ph15040410. Pharmaceuticals (Basel). 2022. PMID: 35455407 Free PMC article.
Here, we report the in vitro antileukemic effects of the sesquiterpene thioalkaloid-enriched fraction of the Nuphar lutea leaf extract (NUP) and a purified thioalkaloid 6,6'-dihydroxythiobinupharidine (DTBN). ...
Here, we report the in vitro antileukemic effects of the sesquiterpene thioalkaloid-enriched fraction of the Nuphar lutea leaf extrac …
Structured Populations of Critically Endangered Yellow Water Lily (Nuphar shimadai Hayata, Nymphaeaceae).
Mantiquilla JA, Lu HY, Shih HC, Ju LP, Shiao MS, Chiang YC. Mantiquilla JA, et al. Plants (Basel). 2022 Sep 19;11(18):2433. doi: 10.3390/plants11182433. Plants (Basel). 2022. PMID: 36145834 Free PMC article.
Yellow water lily (Nuphar shimadai Hayata) is a critically endangered species in Taiwan. ...
Yellow water lily (Nuphar shimadai Hayata) is a critically endangered species in Taiwan. ...
Dimeric Sesquiterpenoids.
Liao SG, Yue JM. Liao SG, et al. Prog Chem Org Nat Prod. 2016;101:1-112. doi: 10.1007/978-3-319-22692-7_1. Prog Chem Org Nat Prod. 2016. PMID: 26659108 Review.
Dearomatization of Heteroarenium Salts with ArBpin Reagents. Application to the Total Synthesis of a Nuphar Alkaloid.
Robinson DJ, Ortiz KG, O'Hare NP, Karimov RR. Robinson DJ, et al. Org Lett. 2022 May 20;24(19):3445-3449. doi: 10.1021/acs.orglett.2c00976. Epub 2022 May 9. Org Lett. 2022. PMID: 35532542
The methodology has enabled the synthesis of 2-heteroaryl-substituted dihydropyridines in high yield and ee, which provided efficient synthetic access to a nuphar alkaloid....
The methodology has enabled the synthesis of 2-heteroaryl-substituted dihydropyridines in high yield and ee, which provided efficient synthe …
153 results