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The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein.
Bonavita R, Scerra G, Di Martino R, Nuzzo S, Polishchuk E, Di Gennaro M, Williams SV, Caporaso MG, Caiazza C, Polishchuk R, D'Agostino M, Fleming A, Renna M. Bonavita R, et al. Among authors: nuzzo s. Hum Mol Genet. 2023 Jul 4;32(14):2269-2291. doi: 10.1093/hmg/ddad047. Hum Mol Genet. 2023. PMID: 36971475 Free PMC article.
Comparative Proteomic Profiling of Secreted Extracellular Vesicles from Breast Fibroadenoma and Malignant Lesions: A Pilot Study.
Pane K, Quintavalle C, Nuzzo S, Ingenito F, Roscigno G, Affinito A, Scognamiglio I, Pattanayak B, Gallo E, Accardo A, Thomas G, Minic Z, Berezovski MV, Franzese M, Condorelli G. Pane K, et al. Among authors: nuzzo s. Int J Mol Sci. 2022 Apr 3;23(7):3989. doi: 10.3390/ijms23073989. Int J Mol Sci. 2022. PMID: 35409352 Free PMC article.
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes.
Esposito CL, Quintavalle C, Ingenito F, Rotoli D, Roscigno G, Nuzzo S, Thomas R, Catuogno S, de Franciscis V, Condorelli G. Esposito CL, et al. Among authors: nuzzo s. Mol Ther Nucleic Acids. 2021 Jan 20;23:982-994. doi: 10.1016/j.omtn.2021.01.012. eCollection 2021 Mar 5. Mol Ther Nucleic Acids. 2021. PMID: 33614245 Free PMC article.
Selection of RNA aptamers targeting hypoxia in cancer.
Nuzzo S, Iaboni M, Ibba ML, Rienzo A, Musumeci D, Franzese M, Roscigno G, Affinito A, Petrillo G, Quintavalle C, Ciccone G, Esposito CL, Catuogno S. Nuzzo S, et al. Front Mol Biosci. 2022 Sep 14;9:956935. doi: 10.3389/fmolb.2022.956935. eCollection 2022. Front Mol Biosci. 2022. PMID: 36188221 Free PMC article.
Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer.
Scognamiglio I, Cocca L, Puoti I, Palma F, Ingenito F, Quintavalle C, Affinito A, Roscigno G, Nuzzo S, Chianese RV, Belli S, Thomas G, Schomann T, Chan A, Stoppelli MP, Condorelli G. Scognamiglio I, et al. Among authors: nuzzo s. Mol Ther Nucleic Acids. 2022 Feb 22;28:17-31. doi: 10.1016/j.omtn.2022.02.013. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35317202 Free PMC article.
miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer.
Palma F, Affinito A, Nuzzo S, Roscigno G, Scognamiglio I, Ingenito F, Martinez L, Franzese M, Zanfardino M, Soricelli A, Fiorelli A, Condorelli G, Quintavalle C. Palma F, et al. Among authors: nuzzo s. Cancer Gene Ther. 2021 May;28(5):413-426. doi: 10.1038/s41417-020-00224-1. Epub 2020 Sep 18. Cancer Gene Ther. 2021. PMID: 32948832 Free PMC article.
MCT4-driven CAF-mediated metabolic reprogramming in breast cancer microenvironment is a vulnerability targetable by miR-425-5p.
Affinito A, Quintavalle C, Chianese RV, Roscigno G, Fiore D, D'Argenio V, Thomas G, Savarese A, Ingenito F, Cocca L, Nuzzo S, Berezovski MV, Stoppelli MP, Condorelli G. Affinito A, et al. Among authors: nuzzo s. Cell Death Discov. 2024 Mar 14;10(1):140. doi: 10.1038/s41420-024-01910-x. Cell Death Discov. 2024. PMID: 38485929 Free PMC article.
445 results