O'Connell O - Search Results

1

Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications.

Gonzalez-Perez MP, Peters PJ, O'Connell O, Silva N, Harbison C, Cummings Macri S, Kaliyaperumal S, Luzuriaga K, Clapham PR. Gonzalez-Perez MP, et al. J Virol. 2017 Sep 27;91(20):e00755-17. doi: 10.1128/JVI.00755-17. Print 2017 Oct 15. J Virol. 2017. PMID: 28768859 Free PMC article.

2

Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue.

Gonzalez-Perez MP, O'Connell O, Lin R, Sullivan WM, Bell J, Simmonds P, Clapham PR. Gonzalez-Perez MP, et al. Retrovirology. 2012 Mar 15;9:20. doi: 10.1186/1742-4690-9-20. Retrovirology. 2012. PMID: 22420378 Free PMC article.

3

Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism.

O'Connell O, Repik A, Reeves JD, Gonzalez-Perez MP, Quitadamo B, Anton ED, Duenas-Decamp M, Peters P, Lin R, Zolla-Pazner S, Corti D, Wallace A, Wang S, Kong XP, Lu S, Clapham PR. O'Connell O, et al. J Virol. 2013 Jan;87(1):187-98. doi: 10.1128/JVI.01834-12. Epub 2012 Oct 10. J Virol. 2013. PMID: 23055568 Free PMC article.

4

HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.

Quitadamo B, Peters PJ, Repik A, O'Connell O, Mou Z, Koch M, Somasundaran M, Brody R, Luzuriaga K, Wallace A, Wang S, Lu S, McCauley S, Luban J, Duenas-Decamp M, Gonzalez-Perez MP, Clapham PR. Quitadamo B, et al. J Virol. 2018 Jan 2;92(2):e00841-17. doi: 10.1128/JVI.00841-17. Print 2018 Jan 15. J Virol. 2018. PMID: 29118121 Free PMC article.

5

Ultradeep single-molecule real-time sequencing of HIV envelope reveals complete compartmentalization of highly macrophage-tropic R5 proviral variants in brain and CXCR4-using variants in immune and peripheral tissues.

Brese RL, Gonzalez-Perez MP, Koch M, O'Connell O, Luzuriaga K, Somasundaran M, Clapham PR, Dollar JJ, Nolan DJ, Rose R, Lamers SL. Brese RL, et al. J Neurovirol. 2018 Aug;24(4):439-453. doi: 10.1007/s13365-018-0633-5. Epub 2018 Apr 23. J Neurovirol. 2018. PMID: 29687407 Free PMC article.

6

HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages.

Musich T, O'Connell O, Gonzalez-Perez MP, Derdeyn CA, Peters PJ, Clapham PR. Musich T, et al. Retrovirology. 2015 Mar 14;12:25. doi: 10.1186/s12977-015-0141-0. Retrovirology. 2015. PMID: 25809903 Free PMC article.

7

Targeted Delivery of Glucan Particle Encapsulated Gallium Nanoparticles Inhibits HIV Growth in Human Macrophages.

Soto ER, O'Connell O, Dikengil F, Peters PJ, Clapham PR, Ostroff GR. Soto ER, et al. J Drug Deliv. 2016;2016:8520629. doi: 10.1155/2016/8520629. Epub 2016 Nov 14. J Drug Deliv. 2016. PMID: 27965897 Free PMC article.

8

The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies.

Dueñas-Decamp MJ, O'Connell OJ, Corti D, Zolla-Pazner S, Clapham PR. Dueñas-Decamp MJ, et al. Retrovirology. 2012 Jan 27;9:9. doi: 10.1186/1742-4690-9-9. Retrovirology. 2012. PMID: 22284192 Free PMC article.

9

A national evaluation of recurrent miscarriage care services.

Hennessy M, Linehan L, Flannery C, Cotter R, O'Connell O, O'Donoghue K. Hennessy M, et al. Among authors: o connell o. Ir Med J. 2023 Jan 19;116(No.1):16. Ir Med J. 2023. PMID: 36916785 No abstract available.

10

Bereaved parents involvement in maternity hospital perinatal death review processes: 'Nobody even thought to ask us anything'.

Helps Ä, O'Donoghue K, O'Connell O, Leitao S. Helps Ä, et al. Among authors: o connell o. Health Expect. 2023 Feb;26(1):183-198. doi: 10.1111/hex.13645. Epub 2022 Nov 6. Health Expect. 2023. PMID: 36335583 Free PMC article. Review.

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