O'Connor KC - Search Results

1

Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production.

Cotzomi E, Stathopoulos P, Lee CS, Ritchie AM, Soltys JN, Delmotte FR, Oe T, Sng J, Jiang R, Ma AK, Vander Heiden JA, Kleinstein SH, Levy M, Bennett JL, Meffre E, O'Connor KC. Cotzomi E, et al. Brain. 2019 Jun 1;142(6):1598-1615. doi: 10.1093/brain/awz106. Brain. 2019. PMID: 31056665 Free PMC article.

2

Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid.

Owens GP, Bennett JL, Lassmann H, O'Connor KC, Ritchie AM, Shearer A, Lam C, Yu X, Birlea M, DuPree C, Williamson RA, Hafler DA, Burgoon MP, Gilden D. Owens GP, et al. Ann Neurol. 2009 Jun;65(6):639-49. doi: 10.1002/ana.21641. Ann Neurol. 2009. PMID: 19557869 Free PMC article.

3

Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis.

Lovato L, Willis SN, Rodig SJ, Caron T, Almendinger SE, Howell OW, Reynolds R, O'Connor KC, Hafler DA. Lovato L, et al. Brain. 2011 Feb;134(Pt 2):534-41. doi: 10.1093/brain/awq350. Epub 2011 Jan 7. Brain. 2011. PMID: 21216828 Free PMC article.

4

Specific peripheral B cell tolerance defects in patients with multiple sclerosis.

Kinnunen T, Chamberlain N, Morbach H, Cantaert T, Lynch M, Preston-Hurlburt P, Herold KC, Hafler DA, O'Connor KC, Meffre E. Kinnunen T, et al. J Clin Invest. 2013 Jun;123(6):2737-41. doi: 10.1172/JCI68775. Epub 2013 May 15. J Clin Invest. 2013. PMID: 23676463 Free PMC article.

5

Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis.

Querol L, Clark PL, Bailey MA, Cotsapas C, Cross AH, Hafler DA, Kleinstein SH, Lee JY, Yaari G, Willis SN, O'Connor KC. Querol L, et al. Neurology. 2013 Sep 10;81(11):956-63. doi: 10.1212/WNL.0b013e3182a43b48. Epub 2013 Aug 6. Neurology. 2013. PMID: 23921886 Free PMC article.

6

The immune cell infiltrate populating meningiomas is composed of mature, antigen-experienced T and B cells.

Fang L, Lowther DE, Meizlish ML, Anderson RC, Bruce JN, Devine L, Huttner AJ, Kleinstein SH, Lee JY, Stern JN, Yaari G, Lovato L, Cronk KM, O'Connor KC. Fang L, et al. Neuro Oncol. 2013 Nov;15(11):1479-90. doi: 10.1093/neuonc/not110. Epub 2013 Aug 26. Neuro Oncol. 2013. PMID: 23978377 Free PMC article.

7

Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data.

Yaari G, Vander Heiden JA, Uduman M, Gadala-Maria D, Gupta N, Stern JN, O'Connor KC, Hafler DA, Laserson U, Vigneault F, Kleinstein SH. Yaari G, et al. Front Immunol. 2013 Nov 15;4:358. doi: 10.3389/fimmu.2013.00358. eCollection 2013. Front Immunol. 2013. PMID: 24298272 Free PMC article.

8

pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires.

Vander Heiden JA, Yaari G, Uduman M, Stern JN, O'Connor KC, Hafler DA, Vigneault F, Kleinstein SH. Vander Heiden JA, et al. Bioinformatics. 2014 Jul 1;30(13):1930-2. doi: 10.1093/bioinformatics/btu138. Epub 2014 Mar 10. Bioinformatics. 2014. PMID: 24618469 Free PMC article.

9

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes.

Stern JN, Yaari G, Vander Heiden JA, Church G, Donahue WF, Hintzen RQ, Huttner AJ, Laman JD, Nagra RM, Nylander A, Pitt D, Ramanan S, Siddiqui BA, Vigneault F, Kleinstein SH, Hafler DA, O'Connor KC. Stern JN, et al. Sci Transl Med. 2014 Aug 6;6(248):248ra107. doi: 10.1126/scitranslmed.3008879. Sci Transl Med. 2014. PMID: 25100741 Free PMC article.

10

B lymphocytes in neuromyelitis optica.

Bennett JL, O'Connor KC, Bar-Or A, Zamvil SS, Hemmer B, Tedder TF, von Büdingen HC, Stuve O, Yeaman MR, Smith TJ, Stadelmann C. Bennett JL, et al. Neurol Neuroimmunol Neuroinflamm. 2015 May 7;2(3):e104. doi: 10.1212/NXI.0000000000000104. eCollection 2015 Jun. Neurol Neuroimmunol Neuroinflamm. 2015. PMID: 25977932 Free PMC article. Review.

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