O'Connor P - Search Results

1

Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1.

Blasina A, Hallin J, Chen E, Arango ME, Kraynov E, Register J, Grant S, Ninkovic S, Chen P, Nichols T, O'Connor P, Anderes K. Blasina A, et al. Mol Cancer Ther. 2008 Aug;7(8):2394-404. doi: 10.1158/1535-7163.MCT-07-2391. Mol Cancer Ther. 2008. PMID: 18723486

2

Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy.

Zhang C, Lundgren K, Yan Z, Arango ME, Price S, Huber A, Higgins J, Troche G, Skaptason J, Koudriakova T, Nonomiya J, Yang M, O'Connor P, Bender S, Los G, Lewis C, Jessen B. Zhang C, et al. Mol Cancer Ther. 2008 Apr;7(4):818-28. doi: 10.1158/1535-7163.MCT-07-0440. Mol Cancer Ther. 2008. PMID: 18413795

3

The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation.

Chen P, Luo C, Deng Y, Ryan K, Register J, Margosiak S, Tempczyk-Russell A, Nguyen B, Myers P, Lundgren K, Kan CC, O'Connor PM. Chen P, et al. Cell. 2000 Mar 17;100(6):681-92. doi: 10.1016/s0092-8674(00)80704-7. Cell. 2000. PMID: 10761933 Free article.

4

Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models.

Thompson CB, Shepard HM, O'Connor PM, Kadhim S, Jiang P, Osgood RJ, Bookbinder LH, Li X, Sugarman BJ, Connor RJ, Nadjsombati S, Frost GI. Thompson CB, et al. Mol Cancer Ther. 2010 Nov;9(11):3052-64. doi: 10.1158/1535-7163.MCT-10-0470. Epub 2010 Oct 26. Mol Cancer Ther. 2010. PMID: 20978165

5

Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.

Hu-Lowe DD, Zou HY, Grazzini ML, Hallin ME, Wickman GR, Amundson K, Chen JH, Rewolinski DA, Yamazaki S, Wu EY, McTigue MA, Murray BW, Kania RS, O'Connor P, Shalinsky DR, Bender SL. Hu-Lowe DD, et al. Clin Cancer Res. 2008 Nov 15;14(22):7272-83. doi: 10.1158/1078-0432.CCR-08-0652. Clin Cancer Res. 2008. PMID: 19010843

6

Discovering novel anticancer drugs: practical aspects and recent advances.

Lewis CT, O'Connor PM. Lewis CT, et al. Methods Mol Biol. 2003;223:425-63. doi: 10.1385/1-59259-329-1:425. Methods Mol Biol. 2003. PMID: 12777744 Review. No abstract available.

7

The Evolutionary Transition of the RNA World to Obcells to Cellular-Based Life.

O'Connor PBF. O'Connor PBF. J Mol Evol. 2024 Apr 29. doi: 10.1007/s00239-024-10171-2. Online ahead of print. J Mol Evol. 2024. PMID: 38683368

8

Genetic interaction between TTG2 and AtPLC1 reveals a role for phosphoinositide signaling in a co-regulated suite of Arabidopsis epidermal pathways.

Goldberg A, O'Connor P, Gonzalez C, Ouren M, Rivera L, Radde N, Nguyen M, Ponce-Herrera F, Lloyd A, Gonzalez A. Goldberg A, et al. Among authors: o connor p. Sci Rep. 2024 Apr 28;14(1):9752. doi: 10.1038/s41598-024-60530-8. Sci Rep. 2024. PMID: 38679676 Free PMC article.

9

Strategies that facilitate the delivery of exceptionally good patient care in general practice: a qualitative study with patients and primary care professionals.

O'Malley R, O'Connor P, Lydon S. O'Malley R, et al. Among authors: o connor p. BMC Prim Care. 2024 Apr 27;25(1):141. doi: 10.1186/s12875-024-02352-1. BMC Prim Care. 2024. PMID: 38678200 Free PMC article.

10

Risk Factors and Modifiers for Cardiovascular Disease Assessment of Patients with Heterozygous Familial Hypercholesterolaemia.

Malone R, Savage S, Crowley V, Hennessy M, O'Connor P, Kennedy C. Malone R, et al. Among authors: o connor p. J Clin Med. 2024 Apr 14;13(8):2270. doi: 10.3390/jcm13082270. J Clin Med. 2024. PMID: 38673543 Free PMC article.

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