O'Garra A - Search Results

1

Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Th1 and Th2 cells.

Castro AG, Hauser TM, Cocks BG, Abrams J, Zurawski S, Churakova T, Zonin F, Robinson D, Tangye SG, Aversa G, Nichols KE, de Vries JE, Lanier LL, O'Garra A. Castro AG, et al. J Immunol. 1999 Dec 1;163(11):5860-70. J Immunol. 1999. PMID: 10570270

2

IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice.

Shibuya K, Robinson D, Zonin F, Hartley SB, Macatonia SE, Somoza C, Hunter CA, Murphy KM, O'Garra A. Shibuya K, et al. J Immunol. 1998 Feb 15;160(4):1708-16. J Immunol. 1998. PMID: 9469428

3

IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18.

Debets R, Timans JC, Churakowa T, Zurawski S, de Waal Malefyt R, Moore KW, Abrams JS, O'Garra A, Bazan JF, Kastelein RA. Debets R, et al. J Immunol. 2000 Nov 1;165(9):4950-6. doi: 10.4049/jimmunol.165.9.4950. J Immunol. 2000. PMID: 11046021

4

Further checkpoints in Th1 development.

Robinson DS, O'Garra A. Robinson DS, et al. Immunity. 2002 Jun;16(6):755-8. doi: 10.1016/s1074-7613(02)00331-x. Immunity. 2002. PMID: 12121657 Free article. Review.

5

Biological properties of interleukin 10.

Howard M, O'Garra A, Ishida H, de Waal Malefyt R, de Vries J. Howard M, et al. J Clin Immunol. 1992 Jul;12(4):239-47. doi: 10.1007/BF00918147. J Clin Immunol. 1992. PMID: 1512298 Review. No abstract available.

6

The BCL1 B lymphoma responds to IL-4, IL-5, and GM-CSF.

O'Garra A, Barbis D, Wu J, Hodgkin PD, Abrams J, Howard M. O'Garra A, et al. Cell Immunol. 1989 Oct 1;123(1):189-200. doi: 10.1016/0008-8749(89)90279-7. Cell Immunol. 1989. PMID: 2673547

7

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

Robinson D, Shibuya K, Mui A, Zonin F, Murphy E, Sana T, Hartley SB, Menon S, Kastelein R, Bazan F, O'Garra A. Robinson D, et al. Immunity. 1997 Oct;7(4):571-81. doi: 10.1016/s1074-7613(00)80378-7. Immunity. 1997. PMID: 9354477 Free article.

8

GATA-3 significantly downregulates IFN-gamma production from developing Th1 cells in addition to inducing IL-4 and IL-5 levels.

Ferber IA, Lee HJ, Zonin F, Heath V, Mui A, Arai N, O'Garra A. Ferber IA, et al. Clin Immunol. 1999 May;91(2):134-44. doi: 10.1006/clim.1999.4718. Clin Immunol. 1999. PMID: 10227805

9

Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only in the presence of lipopolysaccharide.

Castro AG, Neighbors M, Hurst SD, Zonin F, Silva RA, Murphy E, Liu YJ, O'Garra A. Castro AG, et al. J Exp Med. 2000 Nov 20;192(10):1529-34. doi: 10.1084/jem.192.10.1529. J Exp Med. 2000. PMID: 11085755 Free PMC article.

10

A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production.

Neighbors M, Xu X, Barrat FJ, Ruuls SR, Churakova T, Debets R, Bazan JF, Kastelein RA, Abrams JS, O'Garra A. Neighbors M, et al. J Exp Med. 2001 Aug 6;194(3):343-54. doi: 10.1084/jem.194.3.343. J Exp Med. 2001. PMID: 11489953 Free PMC article.

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