O'Kane C - Search Results

1

Emerging pharmacological therapies for ARDS: COVID-19 and beyond.

Horie S, McNicholas B, Rezoagli E, Pham T, Curley G, McAuley D, O'Kane C, Nichol A, Dos Santos C, Rocco PRM, Bellani G, Laffey JG. Horie S, et al. Intensive Care Med. 2020 Dec;46(12):2265-2283. doi: 10.1007/s00134-020-06141-z. Epub 2020 Jul 11. Intensive Care Med. 2020. PMID: 32654006 Free PMC article.

2

Keratinocyte growth factor in acute lung injury--a work in progress.

O'Kane CM, Thickett DR, McAuley DF. O'Kane CM, et al. Crit Care Med. 2009 May;37(5):1813-4. doi: 10.1097/CCM.0b013e3181a1a927. Crit Care Med. 2009. PMID: 19373057 No abstract available.

3

Comment on "Statin administration did not influence the progression of lung injury or associated organ failures in a cohort of patients with acute lung injury".

Shyamsundar M, Craig T, O'Kane C, McAuley D. Shyamsundar M, et al. Intensive Care Med. 2009 Aug;35(8):1494-5; author reply 1496. doi: 10.1007/s00134-009-1506-4. Epub 2009 May 14. Intensive Care Med. 2009. PMID: 19440692 No abstract available.

4

Salbutamol up-regulates matrix metalloproteinase-9 in the alveolar space in the acute respiratory distress syndrome.

O'Kane CM, McKeown SW, Perkins GD, Bassford CR, Gao F, Thickett DR, McAuley DF. O'Kane CM, et al. Crit Care Med. 2009 Jul;37(7):2242-9. doi: 10.1097/CCM.0b013e3181a5506c. Crit Care Med. 2009. PMID: 19487934 Clinical Trial.

5

Novel pulmonary biomarkers in the diagnosis of VAP.

Johnston P, McAuley DF, O'Kane CM. Johnston P, et al. Thorax. 2010 Mar;65(3):190-2. doi: 10.1136/thx.2009.127308. Thorax. 2010. PMID: 20335284 No abstract available.

6

Benefits of statins in the critically ill: promising but not proven.

McGuigan PJ, O'Kane CM, McAuley DF. McGuigan PJ, et al. Crit Care Med. 2011 Jun;39(6):1599-600. doi: 10.1097/CCM.0b013e31821489fd. Crit Care Med. 2011. PMID: 21610648 No abstract available.

7

Evolution of the inflammatory and fibroproliferative responses during resolution and repair after ventilator-induced lung injury in the rat.

Curley GF, Contreras M, Higgins B, O'Kane C, McAuley DF, O'Toole D, Laffey JG. Curley GF, et al. Anesthesiology. 2011 Nov;115(5):1022-32. doi: 10.1097/ALN.0b013e31823422c9. Anesthesiology. 2011. PMID: 21952251 Free article.

8

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial.

McAuley DF, Laffey JG, O'Kane CM, Cross M, Perkins GD, Murphy L, McNally C, Crealey G, Stevenson M; HARP-2 investigators; Irish Critical Care Trials Group. McAuley DF, et al. Trials. 2012 Sep 17;13:170. doi: 10.1186/1745-6215-13-170. Trials. 2012. PMID: 22985805 Free PMC article. Clinical Trial.

9

Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury.

Kerrin A, Weldon S, Chung AH, Craig T, Simpson AJ, O'Kane CM, McAuley DF, Taggart CC. Kerrin A, et al. Thorax. 2013 Apr;68(4):315-21. doi: 10.1136/thoraxjnl-2012-202536. Epub 2012 Dec 14. Thorax. 2013. PMID: 23242946

10

A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.

Small DM, Zani ML, Quinn DJ, Dallet-Choisy S, Glasgow AM, O'Kane C, McAuley DF, McNally P, Weldon S, Moreau T, Taggart CC. Small DM, et al. Mol Ther. 2015 Jan;23(1):24-31. doi: 10.1038/mt.2014.162. Epub 2014 Sep 5. Mol Ther. 2015. PMID: 25189740 Free PMC article.

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