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Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients.
Michelakis ED, Gurtu V, Webster L, Barnes G, Watson G, Howard L, Cupitt J, Paterson I, Thompson RB, Chow K, O'Regan DP, Zhao L, Wharton J, Kiely DG, Kinnaird A, Boukouris AE, White C, Nagendran J, Freed DH, Wort SJ, Gibbs JSR, Wilkins MR. Michelakis ED, et al. Sci Transl Med. 2017 Oct 25;9(413):eaao4583. doi: 10.1126/scitranslmed.aao4583. Sci Transl Med. 2017. PMID: 29070699 Free article. Clinical Trial.
Fractal Analysis of Right Ventricular Trabeculae in Pulmonary Hypertension.
Dawes TJW, Cai J, Quinlan M, de Marvao A, Ostrowski PJ, Tokarczuk PF, Watson GMJ, Wharton J, Howard LSGE, Gibbs JSR, Cook SA, Wilkins MR, O'Regan DP. Dawes TJW, et al. Radiology. 2018 Aug;288(2):386-395. doi: 10.1148/radiol.2018172821. Epub 2018 Jun 5. Radiology. 2018. PMID: 29869959 Free article.
A population-based phenome-wide association study of cardiac and aortic structure and function.
Bai W, Suzuki H, Huang J, Francis C, Wang S, Tarroni G, Guitton F, Aung N, Fung K, Petersen SE, Piechnik SK, Neubauer S, Evangelou E, Dehghan A, O'Regan DP, Wilkins MR, Guo Y, Matthews PM, Rueckert D. Bai W, et al. Nat Med. 2020 Oct;26(10):1654-1662. doi: 10.1038/s41591-020-1009-y. Epub 2020 Aug 24. Nat Med. 2020. PMID: 32839619 Free PMC article.
Validation of Artificial Intelligence Cardiac MRI Measurements: Relationship to Heart Catheterization and Mortality Prediction.
Alabed S, Alandejani F, Dwivedi K, Karunasaagarar K, Sharkey M, Garg P, de Koning PJH, Tóth A, Shahin Y, Johns C, Mamalakis M, Stott S, Capener D, Wood S, Metherall P, Rothman AMK, Condliffe R, Hamilton N, Wild JM, O'Regan DP, Lu H, Kiely DG, van der Geest RJ, Swift AJ. Alabed S, et al. Radiology. 2022 Oct;305(1):68-79. doi: 10.1148/radiol.212929. Epub 2022 Jun 14. Radiology. 2022. PMID: 35699578 Free PMC article.
Environmental and genetic predictors of human cardiovascular ageing.
Shah M, de A Inácio MH, Lu C, Schiratti PR, Zheng SL, Clement A, de Marvao A, Bai W, King AP, Ware JS, Wilkins MR, Mielke J, Elci E, Kryukov I, McGurk KA, Bender C, Freitag DF, O'Regan DP. Shah M, et al. Nat Commun. 2023 Aug 21;14(1):4941. doi: 10.1038/s41467-023-40566-6. Nat Commun. 2023. PMID: 37604819 Free PMC article.
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination.
Liew F, Talwar S, Cross A, Willett BJ, Scott S, Logan N, Siggins MK, Swieboda D, Sidhu JK, Efstathiou C, Moore SC, Davis C, Mohamed N, Nunag J, King C, Thompson AAR, Rowland-Jones SL, Docherty AB, Chalmers JD, Ho LP, Horsley A, Raman B, Poinasamy K, Marks M, Kon OM, Howard L, Wootton DG, Dunachie S, Quint JK, Evans RA, Wain LV, Fontanella S, de Silva TI, Ho A, Harrison E, Baillie JK, Semple MG, Brightling C, Thwaites RS, Turtle L, Openshaw PJM; ISARIC4C Investigators; PHOSP-COVID collaborative group. Liew F, et al. EBioMedicine. 2023 Jan;87:104402. doi: 10.1016/j.ebiom.2022.104402. Epub 2022 Dec 19. EBioMedicine. 2023. PMID: 36543718 Free PMC article.
The relationship between synaptic density marker SV2A, glutamate and N-acetyl aspartate levels in healthy volunteers and schizophrenia: a multimodal PET and magnetic resonance spectroscopy brain imaging study.
Onwordi EC, Whitehurst T, Mansur A, Statton B, Berry A, Quinlan M, O'Regan DP, Rogdaki M, Marques TR, Rabiner EA, Gunn RN, Vernon AC, Natesan S, Howes OD. Onwordi EC, et al. Transl Psychiatry. 2021 Jul 17;11(1):393. doi: 10.1038/s41398-021-01515-3. Transl Psychiatry. 2021. PMID: 34282130 Free PMC article.
150 results