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Page 1
Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors.
Bioorg Med Chem Lett. 2008 Oct 15;18(20):5487-92. doi: 10.1016/j.bmcl.2008.09.024. Epub 2008 Sep 10.
Bioorg Med Chem Lett. 2008.
PMID: 18815031
Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors.
Byth KF, Culshaw JD, Green S, Oakes SE, Thomas AP.
Byth KF, et al. Among authors: oakes se.
Bioorg Med Chem Lett. 2004 May 3;14(9):2245-8. doi: 10.1016/j.bmcl.2004.02.015.
Bioorg Med Chem Lett. 2004.
PMID: 15081017
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Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors.
Byth KF, Cooper N, Culshaw JD, Heaton DW, Oakes SE, Minshull CA, Norman RA, Pauptit RA, Tucker JA, Breed J, Pannifer A, Rowsell S, Stanway JJ, Valentine AL, Thomas AP.
Byth KF, et al. Among authors: oakes se.
Bioorg Med Chem Lett. 2004 May 3;14(9):2249-52. doi: 10.1016/j.bmcl.2004.02.008.
Bioorg Med Chem Lett. 2004.
PMID: 15081018
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AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts.
Byth KF, Thomas A, Hughes G, Forder C, McGregor A, Geh C, Oakes S, Green C, Walker M, Newcombe N, Green S, Growcott J, Barker A, Wilkinson RW.
Byth KF, et al.
Mol Cancer Ther. 2009 Jul;8(7):1856-66. doi: 10.1158/1535-7163.MCT-08-0836. Epub 2009 Jun 9.
Mol Cancer Ther. 2009.
PMID: 19509270
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The cellular phenotype of AZ703, a novel selective imidazo[1,2-a]pyridine cyclin-dependent kinase inhibitor.
Byth KF, Geh C, Forder CL, Oakes SE, Thomas AP.
Byth KF, et al. Among authors: oakes se.
Mol Cancer Ther. 2006 Mar;5(3):655-64. doi: 10.1158/1535-7163.MCT-05-0205.
Mol Cancer Ther. 2006.
PMID: 16546980
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Anomalous results on using an inhibitor method for the determination of pancreatic isoenzymes.
Gordon S, Cooper G, Murray W, Campbell R, Oakes S.
Gordon S, et al.
Clin Chem. 1984 Feb;30(2):339-40.
Clin Chem. 1984.
PMID: 6198109
No abstract available.
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