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Cryopreservation of Primary Mouse Neurons: The Benefit of Neurostore Cryoprotective Medium.
Front Cell Neurosci. 2018 Mar 22;12:81. doi: 10.3389/fncel.2018.00081. eCollection 2018.
Front Cell Neurosci. 2018.
PMID: 29623032
Free PMC article.
Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors.
Volta M, Lavdas AA, Obergasteiger J, Überbacher C, Picard A, Pramstaller PP, Hicks AA, Corti C.
Volta M, et al. Among authors: obergasteiger j.
Cell Signal. 2017 Jan;30:82-91. doi: 10.1016/j.cellsig.2016.11.012. Epub 2016 Nov 18.
Cell Signal. 2017.
PMID: 27871937
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A new hypothesis for Parkinson's disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics.
Obergasteiger J, Frapporti G, Pramstaller PP, Hicks AA, Volta M.
Obergasteiger J, et al.
Mol Neurodegener. 2018 Aug 2;13(1):40. doi: 10.1186/s13024-018-0273-5.
Mol Neurodegener. 2018.
PMID: 30071902
Free PMC article.
Review.
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Kinase inhibition of G2019S-LRRK2 enhances autolysosome formation and function to reduce endogenous alpha-synuclein intracellular inclusions.
Obergasteiger J, Frapporti G, Lamonaca G, Pizzi S, Picard A, Lavdas AA, Pischedda F, Piccoli G, Hilfiker S, Lobbestael E, Baekelandt V, Hicks AA, Corti C, Pramstaller PP, Volta M.
Obergasteiger J, et al.
Cell Death Discov. 2020 Jun 8;6:45. doi: 10.1038/s41420-020-0279-y. eCollection 2020.
Cell Death Discov. 2020.
PMID: 32550012
Free PMC article.
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CADPS2 gene expression is oppositely regulated by LRRK2 and alpha-synuclein.
Obergasteiger J, Überbacher C, Pramstaller PP, Hicks AA, Corti C, Volta M.
Obergasteiger J, et al.
Biochem Biophys Res Commun. 2017 Aug 26;490(3):876-881. doi: 10.1016/j.bbrc.2017.06.134. Epub 2017 Jun 21.
Biochem Biophys Res Commun. 2017.
PMID: 28647363
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Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons.
Überbacher C, Obergasteiger J, Volta M, Venezia S, Müller S, Pesce I, Pizzi S, Lamonaca G, Picard A, Cattelan G, Malpeli G, Zoli M, Beccano-Kelly D, Flynn R, Wade-Martins R, Pramstaller PP, Hicks AA, Cowley SA, Corti C.
Überbacher C, et al. Among authors: obergasteiger j.
Stem Cell Res. 2019 Dec;41:101656. doi: 10.1016/j.scr.2019.101656. Epub 2019 Nov 9.
Stem Cell Res. 2019.
PMID: 31733438
Free PMC article.
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The small GTPase Rit2 modulates LRRK2 kinase activity, is required for lysosomal function and protects against alpha-synuclein neuropathology.
Obergasteiger J, Castonguay AM, Pizzi S, Magnabosco S, Frapporti G, Lobbestael E, Baekelandt V, Hicks AA, Pramstaller PP, Gravel C, Corti C, Lévesque M, Volta M.
Obergasteiger J, et al.
NPJ Parkinsons Dis. 2023 Mar 27;9(1):44. doi: 10.1038/s41531-023-00484-2.
NPJ Parkinsons Dis. 2023.
PMID: 36973269
Free PMC article.
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