Ocain T - Search Results

1

Fragile X syndrome: an update on developing treatment modalities.

Healy A, Rush R, Ocain T. Healy A, et al. Among authors: ocain t. ACS Chem Neurosci. 2011 Aug 17;2(8):402-10. doi: 10.1021/cn200019z. Epub 2011 Mar 22. ACS Chem Neurosci. 2011. PMID: 22860169 Free PMC article. Review.

2

Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis.

Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B. Izmailova ES, et al. Among authors: ocain t. Arthritis Rheum. 2007 Jan;56(1):117-28. doi: 10.1002/art.22303. Arthritis Rheum. 2007. PMID: 17195214 Free article.

3

Quantitation of peripheral blood markers of rat experimental autoimmune encephalomyelitis.

Izmailova E, Walker R, Fitzgerald M, Ocain T, Jaffee B, Healy AM. Izmailova E, et al. Among authors: ocain t. Autoimmunity. 2007 Jul;40(5):355-65. doi: 10.1080/08916930701391579. Autoimmunity. 2007. PMID: 17612897

4

Mice deficient in PKC theta demonstrate impaired in vivo T cell activation and protection from T cell-mediated inflammatory diseases.

Anderson K, Fitzgerald M, Dupont M, Wang T, Paz N, Dorsch M, Healy A, Xu Y, Ocain T, Schopf L, Jaffee B, Picarella D. Anderson K, et al. Among authors: ocain t. Autoimmunity. 2006 Sep;39(6):469-78. doi: 10.1080/08916930600907954. Autoimmunity. 2006. PMID: 17060026

5

IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis.

Schopf L, Savinainen A, Anderson K, Kujawa J, DuPont M, Silva M, Siebert E, Chandra S, Morgan J, Gangurde P, Wen D, Lane J, Xu Y, Hepperle M, Harriman G, Ocain T, Jaffee B. Schopf L, et al. Among authors: ocain t. Arthritis Rheum. 2006 Oct;54(10):3163-73. doi: 10.1002/art.22081. Arthritis Rheum. 2006. PMID: 17009244 Free article.

6

Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta.

Nagashima K, Sasseville VG, Wen D, Bielecki A, Yang H, Simpson C, Grant E, Hepperle M, Harriman G, Jaffee B, Ocain T, Xu Y, Fraser CC. Nagashima K, et al. Among authors: ocain t. Blood. 2006 Jun 1;107(11):4266-73. doi: 10.1182/blood-2005-09-3852. Epub 2006 Jan 26. Blood. 2006. PMID: 16439676 Free article.

7

A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells.

Wen D, Nong Y, Morgan JG, Gangurde P, Bielecki A, Dasilva J, Keaveney M, Cheng H, Fraser C, Schopf L, Hepperle M, Harriman G, Jaffee BD, Ocain TD, Xu Y. Wen D, et al. J Pharmacol Exp Ther. 2006 Jun;317(3):989-1001. doi: 10.1124/jpet.105.097584. Epub 2006 Mar 8. J Pharmacol Exp Ther. 2006. PMID: 16525037

8

Participation of Rip2 in lipopolysaccharide signaling is independent of its kinase activity.

Lu C, Wang A, Dorsch M, Tian J, Nagashima K, Coyle AJ, Jaffee B, Ocain TD, Xu Y. Lu C, et al. J Biol Chem. 2005 Apr 22;280(16):16278-83. doi: 10.1074/jbc.M410114200. Epub 2005 Feb 3. J Biol Chem. 2005. PMID: 15691841 Free article.

9

Small molecule antagonists of the CC chemokine receptor 4 (CCR4).

Burdi DF, Chi S, Mattia K, Harrington C, Shi Z, Chen S, Jacutin-Porte S, Bennett R, Carson K, Yin W, Kansra V, Gonzalo JA, Coyle A, Jaffee B, Ocain T, Hodge M, LaRosa G, Harriman G. Burdi DF, et al. Among authors: ocain t. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3141-5. doi: 10.1016/j.bmcl.2007.03.030. Epub 2007 Mar 15. Bioorg Med Chem Lett. 2007. PMID: 17395464

10

Regulation of IRAK-4 kinase activity via autophosphorylation within its activation loop.

Cheng H, Addona T, Keshishian H, Dahlstrand E, Lu C, Dorsch M, Li Z, Wang A, Ocain TD, Li P, Parsons TF, Jaffee B, Xu Y. Cheng H, et al. Among authors: ocain td. Biochem Biophys Res Commun. 2007 Jan 19;352(3):609-16. doi: 10.1016/j.bbrc.2006.11.068. Epub 2006 Nov 21. Biochem Biophys Res Commun. 2007. PMID: 17141195

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