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The glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 catalyzes the activation of testosterone.
J Steroid Biochem Mol Biol. 2024 Feb;236:106436. doi: 10.1016/j.jsbmb.2023.106436. Epub 2023 Nov 28.
J Steroid Biochem Mol Biol. 2024.
PMID: 38035948
Free article.
Inhibition of the glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess.
Schiffer L, Oestlund I, Snoep JL, Gilligan LC, Taylor AE, Sinclair AJ, Singhal R, Freeman A, Ajjan R, Tiganescu A, Arlt W, Storbeck KH.
Schiffer L, et al. Among authors: oestlund i.
FASEB J. 2024 Apr 15;38(7):e23574. doi: 10.1096/fj.202302131R.
FASEB J. 2024.
PMID: 38551804
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