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Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.
Singh N, Gurav A, Sivaprakasam S, Brady E, Padia R, Shi H, Thangaraju M, Prasad PD, Manicassamy S, Munn DH, Lee JR, Offermanns S, Ganapathy V. Singh N, et al. Among authors: offermanns s. Immunity. 2014 Jan 16;40(1):128-39. doi: 10.1016/j.immuni.2013.12.007. Epub 2014 Jan 9. Immunity. 2014. PMID: 24412617 Free PMC article.
Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility.
Herroeder S, Reichardt P, Sassmann A, Zimmermann B, Jaeneke D, Hoeckner J, Hollmann MW, Fischer KD, Vogt S, Grosse R, Hogg N, Gunzer M, Offermanns S, Wettschureck N. Herroeder S, et al. Among authors: offermanns s. Immunity. 2009 May;30(5):708-20. doi: 10.1016/j.immuni.2009.02.010. Epub 2009 Apr 30. Immunity. 2009. PMID: 19409815 Free article.
GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.
Gambhir D, Ananth S, Veeranan-Karmegam R, Elangovan S, Hester S, Jennings E, Offermanns S, Nussbaum JJ, Smith SB, Thangaraju M, Ganapathy V, Martin PM. Gambhir D, et al. Among authors: offermanns s. Invest Ophthalmol Vis Sci. 2012 Apr 24;53(4):2208-17. doi: 10.1167/iovs.11-8447. Invest Ophthalmol Vis Sci. 2012. PMID: 22427566 Free PMC article.
It ain't over 'til the fat lady sings.
Offermanns S. Offermanns S. Sci Transl Med. 2012 Aug 22;4(148):148fs30. doi: 10.1126/scitranslmed.3004445. Sci Transl Med. 2012. PMID: 22914620
371 results