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A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.
Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z. Jang C, et al. Among authors: oh sf. Nat Med. 2016 Apr;22(4):421-6. doi: 10.1038/nm.4057. Epub 2016 Mar 7. Nat Med. 2016. PMID: 26950361 Free PMC article.
Host immunomodulatory lipids created by symbionts from dietary amino acids.
Oh SF, Praveena T, Song H, Yoo JS, Jung DJ, Erturk-Hasdemir D, Hwang YS, Lee CC, Le Nours J, Kim H, Lee J, Blumberg RS, Rossjohn J, Park SB, Kasper DL. Oh SF, et al. Nature. 2021 Dec;600(7888):302-307. doi: 10.1038/s41586-021-04083-0. Epub 2021 Nov 10. Nature. 2021. PMID: 34759313 Free PMC article.
Gut microbial fatty acid isomerization modulates intraepithelial T cells.
Song X, Zhang H, Zhang Y, Goh B, Bao B, Mello SS, Sun X, Zheng W, Gazzaniga FS, Wu M, Qu F, Yin Q, Gilmore MS, Oh SF, Kasper DL. Song X, et al. Among authors: oh sf. Nature. 2023 Jul;619(7971):837-843. doi: 10.1038/s41586-023-06265-4. Epub 2023 Jun 28. Nature. 2023. PMID: 37380774
Symbionts exploit complex signaling to educate the immune system.
Erturk-Hasdemir D, Oh SF, Okan NA, Stefanetti G, Gazzaniga FS, Seeberger PH, Plevy SE, Kasper DL. Erturk-Hasdemir D, et al. Among authors: oh sf. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26157-26166. doi: 10.1073/pnas.1915978116. Epub 2019 Dec 6. Proc Natl Acad Sci U S A. 2019. PMID: 31811024 Free PMC article.
31 results