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Statins induce calcium-dependent mitochondrial permeability transition.
Velho JA, Okanobo H, Degasperi GR, Matsumoto MY, Alberici LC, Cosso RG, Oliveira HC, Vercesi AE. Velho JA, et al. Among authors: oliveira hc. Toxicology. 2006 Feb 15;219(1-3):124-32. doi: 10.1016/j.tox.2005.11.007. Epub 2005 Dec 15. Toxicology. 2006. PMID: 16343726
Oxidative stress in hypercholesterolemic LDL (low-density lipoprotein) receptor knockout mice is associated with low content of mitochondrial NADP-linked substrates and is partially reversed by citrate replacement.
Paim BA, Velho JA, Castilho RF, Oliveira HC, Vercesi AE. Paim BA, et al. Among authors: oliveira hc. Free Radic Biol Med. 2008 Feb 1;44(3):444-51. doi: 10.1016/j.freeradbiomed.2007.10.005. Epub 2007 Oct 16. Free Radic Biol Med. 2008. PMID: 17991444
351 results