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Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability.
Ge X, Frank-Bertoncelj M, Klein K, McGovern A, Kuret T, Houtman M, Burja B, Micheroli R, Shi C, Marks M, Filer A, Buckley CD, Orozco G, Distler O, Morris AP, Martin P, Eyre S, Ospelt C. Ge X, et al. Among authors: orozco g. Genome Biol. 2021 Aug 25;22(1):247. doi: 10.1186/s13059-021-02460-6. Genome Biol. 2021. PMID: 34433485 Free PMC article.
Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
Orozco G, Hinks A, Eyre S, Ke X, Gibbons LJ, Bowes J, Flynn E, Martin P; Wellcome Trust Case Control Consortium; YEAR consortium; Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Thomson W, Barton A, Worthington J. Orozco G, et al. Hum Mol Genet. 2009 Jul 15;18(14):2693-9. doi: 10.1093/hmg/ddp193. Epub 2009 May 5. Hum Mol Genet. 2009. PMID: 19417005 Free PMC article.
Functional evaluation of TNFAIP3 (A20) in rheumatoid arthritis.
Elsby LM, Orozco G, Denton J, Worthington J, Ray DW, Donn RP. Elsby LM, et al. Among authors: orozco g. Clin Exp Rheumatol. 2010 Sep-Oct;28(5):708-14. Epub 2010 Oct 22. Clin Exp Rheumatol. 2010. PMID: 20822710 Free PMC article.
Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis.
Bowes J, Lawrence R, Eyre S, Panoutsopoulou K, Orozco G, Elliott KS, Ke X, Morris AP; UKRAG; Thomson W, Worthington J, Barton A, Zeggini E. Bowes J, et al. Among authors: orozco g. Hum Genet. 2010 Dec;128(6):627-33. doi: 10.1007/s00439-010-0889-1. Epub 2010 Sep 18. Hum Genet. 2010. PMID: 20852893 Free PMC article.
Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis.
Orozco G, Goh CL, Al Olama AA, Benlloch-Garcia S, Govindasami K, Guy M, Muir KR, Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL, Kote-Jarai Z, Easton DF, Eyre S, Eeles RA. Orozco G, et al. BJU Int. 2013 Jun;111(7):1148-55. doi: 10.1111/j.1464-410X.2012.11492.x. Epub 2012 Sep 18. BJU Int. 2013. PMID: 22985493 Free PMC article.
162 results