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Activation of the CARD8 Inflammasome Requires a Disordered Region.
Cell Rep. 2020 Oct 13;33(2):108264. doi: 10.1016/j.celrep.2020.108264.
Cell Rep. 2020.
PMID: 33053349
Free PMC article.
N-terminal degradation activates the NLRP1B inflammasome.
Chui AJ, Okondo MC, Rao SD, Gai K, Griswold AR, Johnson DC, Ball DP, Taabazuing CY, Orth EL, Vittimberga BA, Bachovchin DA.
Chui AJ, et al. Among authors: orth el.
Science. 2019 Apr 5;364(6435):82-85. doi: 10.1126/science.aau1208. Epub 2019 Mar 14.
Science. 2019.
PMID: 30872531
Free PMC article.
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DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes.
Johnson DC, Okondo MC, Orth EL, Rao SD, Huang HC, Ball DP, Bachovchin DA.
Johnson DC, et al. Among authors: orth el.
Cell Death Dis. 2020 Aug 14;11(8):628. doi: 10.1038/s41419-020-02865-4.
Cell Death Dis. 2020.
PMID: 32796818
Free PMC article.
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Caspase-1 interdomain linker cleavage is required for pyroptosis.
Ball DP, Taabazuing CY, Griswold AR, Orth EL, Rao SD, Kotliar IB, Vostal LE, Johnson DC, Bachovchin DA.
Ball DP, et al. Among authors: orth el.
Life Sci Alliance. 2020 Feb 12;3(3):e202000664. doi: 10.26508/lsa.202000664. Print 2020 Mar.
Life Sci Alliance. 2020.
PMID: 32051255
Free PMC article.
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