Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group.
Robinson MJ, Martin BA, Gootz TD, McGuirk PR, Osheroff N.
Robinson MJ, et al. Among authors: osheroff n.
Antimicrob Agents Chemother. 1992 Apr;36(4):751-6. doi: 10.1128/AAC.36.4.751.
Antimicrob Agents Chemother. 1992.
PMID: 1323952
Free PMC article.
Martin, T.D. Gootz, P.R. McGuirk, M. Moynihan, J.A. Sutcliffe, and N. Osheroff, J. Biol. Chem. 266:14585-14592, 1991) demonstrated that novel 6,8-difluoroquinolones were potent effectors of eukaryotic topoisomerase II. ...Further comparisons of CP-115,955 with CP-11 …
Martin, T.D. Gootz, P.R. McGuirk, M. Moynihan, J.A. Sutcliffe, and N. Osheroff, J. Biol. Chem. 266:14585-14592, 1991) demonstr …