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Oritavancin Pharmacokinetics and Bone Penetration in Rabbits.
Lehoux D, Ostiguy V, Cadieux C, Malouin M, Belanger O, Far AR, Parr TR Jr. Lehoux D, et al. Among authors: ostiguy v. Antimicrob Agents Chemother. 2015 Oct;59(10):6501-5. doi: 10.1128/AAC.00981-15. Epub 2015 Aug 3. Antimicrob Agents Chemother. 2015. PMID: 26239977 Free PMC article.
Linking bisphosphonates to the free amino groups in fluoroquinolones: preparation of osteotropic prodrugs for the prevention of osteomyelitis.
Houghton TJ, Tanaka KS, Kang T, Dietrich E, Lafontaine Y, Delorme D, Ferreira SS, Viens F, Arhin FF, Sarmiento I, Lehoux D, Fadhil I, Laquerre K, Liu J, Ostiguy V, Poirier H, Moeck G, Parr TR Jr, Far AR. Houghton TJ, et al. Among authors: ostiguy v. J Med Chem. 2008 Nov 13;51(21):6955-69. doi: 10.1021/jm801007z. Epub 2008 Oct 4. J Med Chem. 2008. PMID: 18834106
Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis.
Tanaka KS, Houghton TJ, Kang T, Dietrich E, Delorme D, Ferreira SS, Caron L, Viens F, Arhin FF, Sarmiento I, Lehoux D, Fadhil I, Laquerre K, Liu J, Ostiguy V, Poirier H, Moeck G, Parr TR Jr, Rafai Far A. Tanaka KS, et al. Among authors: ostiguy v. Bioorg Med Chem. 2008 Oct 15;16(20):9217-29. doi: 10.1016/j.bmc.2008.09.010. Epub 2008 Sep 9. Bioorg Med Chem. 2008. PMID: 18815051