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The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity.
Jarvela TS, Lam HA, Helwig M, Lorenzen N, Otzen DE, McLean PJ, Maidment NT, Lindberg I. Jarvela TS, et al. Among authors: otzen de. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4708-15. doi: 10.1073/pnas.1601091113. Epub 2016 Jul 25. Proc Natl Acad Sci U S A. 2016. PMID: 27457957 Free PMC article.
Assays for α-synuclein aggregation.
Giehm L, Lorenzen N, Otzen DE. Giehm L, et al. Among authors: otzen de. Methods. 2011 Mar;53(3):295-305. doi: 10.1016/j.ymeth.2010.12.008. Epub 2010 Dec 14. Methods. 2011. PMID: 21163351 Review.
Coexistence of ribbon and helical fibrils originating from hIAPP(20-29) revealed by quantitative nanomechanical atomic force microscopy.
Zhang S, Andreasen M, Nielsen JT, Liu L, Nielsen EH, Song J, Ji G, Sun F, Skrydstrup T, Besenbacher F, Nielsen NC, Otzen DE, Dong M. Zhang S, et al. Among authors: otzen de. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2798-803. doi: 10.1073/pnas.1209955110. Epub 2013 Feb 6. Proc Natl Acad Sci U S A. 2013. PMID: 23388629 Free PMC article.
380 results