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A novel host-protein assay outperforms routine parameters for distinguishing between bacterial and viral lower respiratory tract infections.
Stein M, Lipman-Arens S, Oved K, Cohen A, Bamberger E, Navon R, Boico O, Friedman T, Etshtein L, Paz M, Gottlieb TM, Kriger O, Fonar Y, Pri-Or E, Yacobov R, Dotan Y, Hochberg A, Grupper M, Chistyakov I, Potasman I, Srugo I, Eden E, Klein A. Stein M, et al. Among authors: oved k. Diagn Microbiol Infect Dis. 2018 Mar;90(3):206-213. doi: 10.1016/j.diagmicrobio.2017.11.011. Epub 2017 Nov 24. Diagn Microbiol Infect Dis. 2018. PMID: 29273482
A novel host-proteome signature for distinguishing between acute bacterial and viral infections.
Oved K, Cohen A, Boico O, Navon R, Friedman T, Etshtein L, Kriger O, Bamberger E, Fonar Y, Yacobov R, Wolchinsky R, Denkberg G, Dotan Y, Hochberg A, Reiter Y, Grupper M, Srugo I, Feigin P, Gorfine M, Chistyakov I, Dagan R, Klein A, Potasman I, Eden E. Oved K, et al. PLoS One. 2015 Mar 18;10(3):e0120012. doi: 10.1371/journal.pone.0120012. eCollection 2015. PLoS One. 2015. PMID: 25785720 Free PMC article. Clinical Trial.
Validation of a Novel Assay to Distinguish Bacterial and Viral Infections.
Srugo I, Klein A, Stein M, Golan-Shany O, Kerem N, Chistyakov I, Genizi J, Glazer O, Yaniv L, German A, Miron D, Shachor-Meyouhas Y, Bamberger E, Oved K, Gottlieb TM, Navon R, Paz M, Etshtein L, Boico O, Kronenfeld G, Eden E, Cohen R, Chappuy H, Angoulvant F, Lacroix L, Gervaix A. Srugo I, et al. Among authors: oved k. Pediatrics. 2017 Oct;140(4):e20163453. doi: 10.1542/peds.2016-3453. Epub 2017 Sep 13. Pediatrics. 2017. PMID: 28904072 Clinical Trial.
A host-protein signature is superior to other biomarkers for differentiating between bacterial and viral disease in patients with respiratory infection and fever without source: a prospective observational study.
Ashkenazi-Hoffnung L, Oved K, Navon R, Friedman T, Boico O, Paz M, Kronenfeld G, Etshtein L, Cohen A, Gottlieb TM, Eden E, Chistyakov I, Srugo I, Klein A, Ashkenazi S, Scheuerman O. Ashkenazi-Hoffnung L, et al. Among authors: oved k. Eur J Clin Microbiol Infect Dis. 2018 Jul;37(7):1361-1371. doi: 10.1007/s10096-018-3261-3. Epub 2018 Apr 26. Eur J Clin Microbiol Infect Dis. 2018. PMID: 29700762 Free PMC article.
Observational multi-centre, prospective study to characterize novel pathogen-and host-related factors in hospitalized patients with lower respiratory tract infections and/or sepsis - the "TAILORED-Treatment" study.
van Houten CB, Oved K, Eden E, Cohen A, Engelhard D, Boers S, Kraaij R, Karlsson R, Fernandez D, Gonzalez E, Li Y, Stubbs A, Moore ERB, Hays JP, Bont LJ. van Houten CB, et al. Among authors: oved k. BMC Infect Dis. 2018 Aug 7;18(1):377. doi: 10.1186/s12879-018-3300-9. BMC Infect Dis. 2018. PMID: 30086729 Free PMC article.
Antibiotic misuse in respiratory tract infections in children and adults-a prospective, multicentre study (TAILORED Treatment).
van Houten CB, Cohen A, Engelhard D, Hays JP, Karlsson R, Moore E, Fernández D, Kreisberg R, Collins LV, de Waal W, de Winter-de Groot KM, Wolfs TFW, Meijers P, Luijk B, Oosterheert JJ, Heijligenberg R, Sankatsing SUC, Bossink AWJ, Stubbs A, Stein M, Reisfeld S, Klein A, Rachmilevitch R, Ashkar J, Braverman I, Kartun V, Chistyakov I, Bamberger E, Srugo I, Odeh M, Schiff E, Dotan Y, Boico O, Navon R, Friedman T, Etshtein L, Paz M, Gottlieb TM, Pri-Or E, Kronenfeld G, Simon E, Oved K, Eden E, Bont LJ. van Houten CB, et al. Among authors: oved k. Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):505-514. doi: 10.1007/s10096-018-03454-2. Epub 2019 Feb 1. Eur J Clin Microbiol Infect Dis. 2019. PMID: 30707378 Free PMC article.
Expert panel diagnosis demonstrated high reproducibility as reference standard in infectious diseases.
van Houten CB, Naaktgeboren CA, Ashkenazi-Hoffnung L, Ashkenazi S, Avis W, Chistyakov I, Corigliano T, Galetto A, Gangoiti I, Gervaix A, Glikman D, Ivaskeviciene I, Kuperman AA, Lacroix L, Loeffen Y, Luterbacher F, Meijssen CB, Mintegi S, Nasrallah B, Papan C, van Rossum AMC, Rudolph H, Stein M, Tal R, Tenenbaum T, Usonis V, de Waal W, Weichert S, Wildenbeest JG, de Winter-de Groot KM, Wolfs TFW, Mastboim N, Gottlieb TM, Cohen A, Oved K, Eden E, Feigin PD, Shani L, Bont LJ; IMPRIND consortium. van Houten CB, et al. Among authors: oved k. J Clin Epidemiol. 2019 Aug;112:20-27. doi: 10.1016/j.jclinepi.2019.03.010. Epub 2019 Mar 28. J Clin Epidemiol. 2019. PMID: 30930247
46 results