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Page 1
Understanding the Molecular Genetics of Basal Cell Carcinoma.
Pellegrini C, Maturo MG, Di Nardo L, Ciciarelli V, Gutiérrez García-Rodrigo C, Fargnoli MC. Pellegrini C, et al. Int J Mol Sci. 2017 Nov 22;18(11):2485. doi: 10.3390/ijms18112485. Int J Mol Sci. 2017. PMID: 29165358 Free PMC article. Review.
In addition, emerging reports identified frequent non-coding mutations within the regulatory promoter sequences of the TERT and DPH3-OXNAD1 genes. Thus, it is clear that a more complex genetic network of cancer-associated genes than previously hypothesized is involved in B …
In addition, emerging reports identified frequent non-coding mutations within the regulatory promoter sequences of the TERT and DPH3-OXNA …
Frequent DPH3 promoter mutations in skin cancers.
Denisova E, Heidenreich B, Nagore E, Rachakonda PS, Hosen I, Akrap I, Traves V, García-Casado Z, López-Guerrero JA, Requena C, Sanmartin O, Serra-Guillén C, Llombart B, Guillén C, Ferrando J, Gimeno E, Nordheim A, Hemminki K, Kumar R. Denisova E, et al. Oncotarget. 2015 Nov 3;6(34):35922-30. doi: 10.18632/oncotarget.5771. Oncotarget. 2015. PMID: 26416425 Free PMC article.
Reporter assays carried out in one melanoma cell line for DPH3 and OXNAD1 orientations showed statistically significant increased promoter activity due to -8/-9CC > TT tandem mutations; although, no effect of the mutations on DPH3 and OXNAD1 transcription in tumo …
Reporter assays carried out in one melanoma cell line for DPH3 and OXNAD1 orientations showed statistically significant increased pro …
Comparative genomics reveals putative evidence for high-elevation adaptation in the American pika (Ochotona princeps).
Sjodin BMF, Russello MA. Sjodin BMF, et al. G3 (Bethesda). 2022 Nov 4;12(11):jkac241. doi: 10.1093/g3journal/jkac241. G3 (Bethesda). 2022. PMID: 36087005 Free PMC article. Review.
We further detected 196 positively selected genes, 41 of which have been associated with putative adaptation to hypoxia, cold tolerance, and response to UV following a literature review. In particular, OXNAD1, NRDC, and those genes critical in DNA repair represent importan …
We further detected 196 positively selected genes, 41 of which have been associated with putative adaptation to hypoxia, cold tolerance, and …
Gene Expression Analysis Reveals Age and Ethnicity Signatures Between Young and Old Adults in Human PBMC.
Hu Y, Xu Y, Mao L, Lei W, Xiang J, Gao L, Jiang J, Huang LA, Luo OJ, Duan J, Chen G. Hu Y, et al. Front Aging. 2022 Feb 3;2:797040. doi: 10.3389/fragi.2021.797040. eCollection 2021. Front Aging. 2022. PMID: 35822054 Free PMC article.
In addition, we find the top hub genes including NUDT7, CLPB, OXNAD1, and MLLT3 are shared between Asian and Caucasian aging related modules and further validated in human PBMCs from different age groups. ...
In addition, we find the top hub genes including NUDT7, CLPB, OXNAD1, and MLLT3 are shared between Asian and Caucasian aging related …
New gene targets of PGC-1α and ERRα co-regulation in C2C12 myotubes.
Nsiah-Sefaa A, Brown EL, Russell AP, Foletta VC. Nsiah-Sefaa A, et al. Mol Biol Rep. 2014 Dec;41(12):8009-17. doi: 10.1007/s11033-014-3698-0. Epub 2014 Sep 6. Mol Biol Rep. 2014. PMID: 25192891
Following confirmation of their regulation by PGC-1alpha using qPCR analysis, eight genes were focused on for further investigation (Akr1b10, Rmnd1, 1110008P14Rik, 1700021F05Rik, Mtfp1, Mrm1, Oxnad1 and Cluh). Bioinformatics indicated a number of the genes were linked to a …
Following confirmation of their regulation by PGC-1alpha using qPCR analysis, eight genes were focused on for further investigation (Akr1b10 …
Hypoxia-treated umbilical mesenchymal stem cell alleviates spinal cord ischemia-reperfusion injury in SCI by circular RNA circOXNAD1/ miR-29a-3p/ FOXO3a axis.
Wang X, Li W, Hao M, Yang Y, Xu Y. Wang X, et al. Biochem Biophys Rep. 2023 Mar 20;34:101458. doi: 10.1016/j.bbrep.2023.101458. eCollection 2023 Jul. Biochem Biophys Rep. 2023. PMID: 36969321 Free PMC article.
This work aimed to study the therapeutic potential of hypoxia-induced exosomal circular RNA OXNAD1 from human umbilical cord mesenchymal stem cells (HucMSCs) against SCIR. ...
This work aimed to study the therapeutic potential of hypoxia-induced exosomal circular RNA OXNAD1 from human umbilical cord mesenchy …
Proteomics-Derived Biomarker Panel Facilitates Distinguishing Primary Lung Adenocarcinomas With Intestinal or Mucinous Differentiation From Lung Metastatic Colorectal Cancer.
Liu J, Chang X, Qian L, Chen S, Xue Z, Wu J, Luo D, Huang B, Fan J, Guo T, Nie X. Liu J, et al. Mol Cell Proteomics. 2024 May;23(5):100766. doi: 10.1016/j.mcpro.2024.100766. Epub 2024 Apr 10. Mol Cell Proteomics. 2024. PMID: 38608841 Free PMC article.
A set of ten candidate proteins (high-level expression in lmCRC: CDH17, ATP1B3, GLB1, OXNAD1, LYST, FABP1; high-level expression in PAIM: CK7 (an established marker), NARR, MLPH, S100A14) was ultimately selected to distinguish PAIM from lmCRC by machine learning algorithms …
A set of ten candidate proteins (high-level expression in lmCRC: CDH17, ATP1B3, GLB1, OXNAD1, LYST, FABP1; high-level expression in P …