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Failure of origin activation in response to fork stalling leads to chromosomal instability at fragile sites.
Mol Cell. 2011 Jul 8;43(1):122-31. doi: 10.1016/j.molcel.2011.05.019.
Mol Cell. 2011.
PMID: 21726815
Free article.
Interplay between ATM and ATR in the regulation of common fragile site stability.
Ozeri-Galai E, Schwartz M, Rahat A, Kerem B.
Ozeri-Galai E, et al.
Oncogene. 2008 Apr 3;27(15):2109-17. doi: 10.1038/sj.onc.1210849. Epub 2007 Oct 15.
Oncogene. 2008.
PMID: 17934520
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The complex basis underlying common fragile site instability in cancer.
Ozeri-Galai E, Bester AC, Kerem B.
Ozeri-Galai E, et al.
Trends Genet. 2012 Jun;28(6):295-302. doi: 10.1016/j.tig.2012.02.006. Epub 2012 Mar 31.
Trends Genet. 2012.
PMID: 22465609
Review.
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Interplay between genetic and epigenetic factors governs common fragile site instability in cancer.
Ozeri-Galai E, Tur-Sinai M, Bester AC, Kerem B.
Ozeri-Galai E, et al.
Cell Mol Life Sci. 2014 Dec;71(23):4495-506. doi: 10.1007/s00018-014-1719-8. Epub 2014 Oct 9.
Cell Mol Life Sci. 2014.
PMID: 25297918
Review.
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The presence of extra chromosomes leads to genomic instability.
Passerini V, Ozeri-Galai E, de Pagter MS, Donnelly N, Schmalbrock S, Kloosterman WP, Kerem B, Storchová Z.
Passerini V, et al. Among authors: ozeri galai e.
Nat Commun. 2016 Feb 15;7:10754. doi: 10.1038/ncomms10754.
Nat Commun. 2016.
PMID: 26876972
Free PMC article.
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Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation.
Oren YS, Irony-Tur Sinai M, Golec A, Barchad-Avitzur O, Mutyam V, Li Y, Hong J, Ozeri-Galai E, Hatton A, Leibson C, Carmel L, Reiter J, Sorscher EJ, Wilton SD, Kerem E, Rowe SM, Sermet-Gaudelus I, Kerem B.
Oren YS, et al. Among authors: ozeri galai e.
J Cyst Fibros. 2021 Sep;20(5):865-875. doi: 10.1016/j.jcf.2021.06.003. Epub 2021 Jul 2.
J Cyst Fibros. 2021.
PMID: 34226157
Free PMC article.
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Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation.
Oren YS, Avizur-Barchad O, Ozeri-Galai E, Elgrabli R, Schirelman MR, Blinder T, Stampfer CD, Ordan M, Laselva O, Cohen-Cymberknoh M, Kerem E, Bear CE, Kerem B.
Oren YS, et al. Among authors: ozeri galai e.
J Cyst Fibros. 2022 Jul;21(4):630-636. doi: 10.1016/j.jcf.2021.12.012. Epub 2021 Dec 28.
J Cyst Fibros. 2022.
PMID: 34972649
Free article.
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Delivery Characterization of SPL84 Inhaled Antisense Oligonucleotide Drug for 3849 + 10 kb C- > T Cystic Fibrosis Patients.
Ozeri-Galai E, Friedman L, Barchad-Avitzur O, Markovetz MR, Boone W, Rouillard KR, Stampfer CD, Oren YS, Hill DB, Kerem B, Hart G.
Ozeri-Galai E, et al.
Nucleic Acid Ther. 2023 Oct;33(5):306-318. doi: 10.1089/nat.2023.0015. Epub 2023 Aug 29.
Nucleic Acid Ther. 2023.
PMID: 37643307
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