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Multivalent tyrosine kinase inhibition promotes T cell recruitment to immune-desert gastric cancers by restricting epithelial-mesenchymal transition via tumour-intrinsic IFN-γ signalling.
Cao LL, Lu H, Soutto M, Bhat N, Chen Z, Peng D, Gomaa A, Wang JB, Xie JW, Li P, Zheng CH, Nomura S, Datta J, Merchant N, Chen ZB, Villarino A, Zaika A, Huang CM, El-Rifai W. Cao LL, et al. Gut. 2023 Nov;72(11):2038-2050. doi: 10.1136/gutjnl-2022-329134. Epub 2023 Jul 4. Gut. 2023. PMID: 37402563
Protein adduction causes non-mutational inhibition of p53 tumor suppressor.
Caspa Gokulan R, Paulrasu K, Azfar J, El-Rifai W, Que J, Boutaud OG, Ban Y, Gao Z, Buitrago MG, Dikalov SI, Zaika AI. Caspa Gokulan R, et al. Cell Rep. 2023 Jan 31;42(1):112024. doi: 10.1016/j.celrep.2023.112024. Epub 2023 Jan 23. Cell Rep. 2023. PMID: 36848235 Free PMC article.
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