P01 GM056550/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2004	2
2006	2
2007	4
2008	5
2009	10
2010	8
2011	12
2012	9
2013	11
2014	12
2015	17
2016	16
2017	17
2018	9
2019	10
2020	5
2021	7
2022	1
2023	5
2024	0

1

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.

Prévost J, Chen Y, Zhou F, Tolbert WD, Gasser R, Medjahed H, Nayrac M, Nguyen DN, Gottumukkala S, Hessell AJ, Rao VB, Pozharski E, Huang RK, Matthies D, Finzi A, Pazgier M. Prévost J, et al. Nat Commun. 2023 Oct 23;14(1):6710. doi: 10.1038/s41467-023-42500-2. Nat Commun. 2023. PMID: 37872202 Free PMC article.

2

Irreversible Inactivation of SARS-CoV-2 by Lectin Engagement with Two Glycan Clusters on the Spike Protein.

Nangarlia A, Hassen FF, Canziani G, Bandi P, Talukder C, Zhang F, Krauth D, Gary EN, Weiner DB, Bieniasz P, Navas-Martin S, O'Keefe BR, Ang CG, Chaiken I. Nangarlia A, et al. Biochemistry. 2023 Jul 18;62(14):2115-2127. doi: 10.1021/acs.biochem.3c00109. Epub 2023 Jun 21. Biochemistry. 2023. PMID: 37341186 Free PMC article.

3

Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC.

Ding S, Tolbert WD, Zhu H, Lee D, Marchitto L, Higgins T, Zhao X, Nguyen D, Sherburn R, Richard J, Gendron-Lepage G, Medjahed H, Mohammadi M, Abrams C, Pazgier M, Smith AB 3rd, Finzi A. Ding S, et al. Viruses. 2023 May 17;15(5):1185. doi: 10.3390/v15051185. Viruses. 2023. PMID: 37243271 Free PMC article.

4

Pharmacophore Variants of the Macrocyclic Peptide Triazole Inactivator of HIV-1 Env.

Gupta M, Canziani G, Ang C, Mohammadi M, Abrams CF, Yang D, Smith AB 3rd, Chaiken I. Gupta M, et al. Res Sq [Preprint]. 2023 Apr 20:rs.3.rs-2814722. doi: 10.21203/rs.3.rs-2814722/v1. Res Sq. 2023. PMID: 37131733 Free PMC article. Preprint.

5

Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity.

Laumaea A, Marchitto L, Ding S, Beaudoin-Bussières G, Prévost J, Gasser R, Chatterjee D, Gendron-Lepage G, Medjahed H, Chen HC, Smith AB 3rd, Ding H, Kappes JC, Hahn BH, Kirchhoff F, Richard J, Duerr R, Finzi A. Laumaea A, et al. Cell Rep. 2023 Jan 31;42(1):111983. doi: 10.1016/j.celrep.2022.111983. Epub 2023 Jan 10. Cell Rep. 2023. PMID: 36640355 Free PMC article.

6

HIV-1 Vpu restricts Fc-mediated effector functions in vivo.

Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, Flavell RA, Kirchhoff F, Hahn BH, Smith AB 3rd, Pazgier M, Nussenzweig MC, Kumar P, Finzi A. Prévost J, et al. Cell Rep. 2022 Nov 8;41(6):111624. doi: 10.1016/j.celrep.2022.111624. Cell Rep. 2022. PMID: 36351384 Free PMC article.

7

Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells.

Richard J, Nguyen DN, Tolbert WD, Gasser R, Ding S, Vézina D, Yu Gong S, Prévost J, Gendron-Lepage G, Medjahed H, Gottumukkala S, Finzi A, Pazgier M. Richard J, et al. mBio. 2021 Oct 26;12(5):e0140521. doi: 10.1128/mBio.01405-21. Epub 2021 Sep 28. mBio. 2021. PMID: 34579568 Free PMC article.

8

Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer.

Zhang S, Wang K, Wang WL, Nguyen HT, Chen S, Lu M, Go EP, Ding H, Steinbock RT, Desaire H, Kappes JC, Sodroski J, Mao Y. Zhang S, et al. J Virol. 2021 Nov 23;95(24):e0052921. doi: 10.1128/JVI.00529-21. Epub 2021 Sep 22. J Virol. 2021. PMID: 34549974 Free PMC article.

9

Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus-Cell Entry.

Ang CG, Carter E, Haftl A, Zhang S, Rashad AA, Kutzler M, Abrams CF, Chaiken IM. Ang CG, et al. Microorganisms. 2021 Jun 12;9(6):1286. doi: 10.3390/microorganisms9061286. Microorganisms. 2021. PMID: 34204725 Free PMC article.

10

Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir.

Rajashekar JK, Richard J, Beloor J, Prévost J, Anand SP, Beaudoin-Bussières G, Shan L, Herndler-Brandstetter D, Gendron-Lepage G, Medjahed H, Bourassa C, Gaudette F, Ullah I, Symmes K, Peric A, Lindemuth E, Bibollet-Ruche F, Park J, Chen HC, Kaufmann DE, Hahn BH, Sodroski J, Pazgier M, Flavell RA, Smith AB 3rd, Finzi A, Kumar P. Rajashekar JK, et al. Cell Host Microbe. 2021 Jun 9;29(6):904-916.e6. doi: 10.1016/j.chom.2021.04.014. Epub 2021 May 20. Cell Host Microbe. 2021. PMID: 34019804 Free PMC article.

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