Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 1
2012 2
2015 2
2016 1
2017 1
2018 1
2019 2
2020 1
2021 3
2023 4
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

17 results

Results by year

Filters applied: . Clear all
Page 1
LncRNA PCIR Is an Oncogenic Driver via Strengthen the Binding of TAB3 and PABPC4 in Triple Negative Breast Cancer.
Guo W, Li J, Huang H, Fu F, Lin Y, Wang C. Guo W, et al. Front Oncol. 2021 May 3;11:630300. doi: 10.3389/fonc.2021.630300. eCollection 2021. Front Oncol. 2021. PMID: 34012913 Free PMC article.
RNA pulldown, RNA immunoprecipitation (RIP) and RNA transcriptome sequencing technology (RNA-seq) was performed to identify the associated proteins and related signaling pathways. Mechanistically, higher Lnc-PCIR level of blocks PABPC4 proteasome-dependent ubiquitination d …
RNA pulldown, RNA immunoprecipitation (RIP) and RNA transcriptome sequencing technology (RNA-seq) was performed to identify the associated p …
circFAM134B is a key factor regulating reticulophagy-mediated ferroptosis in hepatocellular carcinoma.
Bi T, Lu Q, Pan X, Dong F, Hu Y, Xu Z, Xiu P, Liu Z, Li J. Bi T, et al. Cell Cycle. 2023 Sep;22(17):1900-1920. doi: 10.1080/15384101.2023.2249302. Epub 2023 Aug 21. Cell Cycle. 2023. PMID: 37603831
RNA pull-down and mass spectrometry analyses suggested that circFAM134B and FAM134B mRNA were enriched with several common interacting proteins. Among them, poly (A) binding protein cytoplasmic 4 (PABPC4) was identified as the most enriched binding partner. It was proven t …
RNA pull-down and mass spectrometry analyses suggested that circFAM134B and FAM134B mRNA were enriched with several common interacting prote …
Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis.
Liu D, Yin B, Wang Q, Ju W, Chen Y, Qiu H, Li J, Peng X, Lu C. Liu D, et al. J Genet Genomics. 2012 Aug 20;39(8):369-74. doi: 10.1016/j.jgg.2012.05.007. Epub 2012 Jun 8. J Genet Genomics. 2012. PMID: 22884093
PABPC4 expression was positively associated with survival outcome, and may have predictive value in the prognosis of patients with colorectal cancer. Taken together, our findings indicate that PABPC4 may play a role in the pathogenesis of colorectal cancer …
PABPC4 expression was positively associated with survival outcome, and may have predictive value in the prognosis of patients with co …
LINC00493-encoded microprotein SMIM26 exerts anti-metastatic activity in renal cell carcinoma.
Meng K, Lu S, Li YY, Hu LL, Zhang J, Cao Y, Wang Y, Zhang CZ, He QY. Meng K, et al. EMBO Rep. 2023 Jun 5;24(6):e56282. doi: 10.15252/embr.202256282. Epub 2023 Apr 3. EMBO Rep. 2023. PMID: 37009826 Free PMC article.
Here, we show that LINC00493-encoded SMIM26, an understudied microprotein localized in mitochondria, is tendentiously downregulated in clear cell renal cell carcinoma (ccRCC) and correlated with poor overall survival. LINC00493 is recognized by RNA-binding protein PABPC4 a …
Here, we show that LINC00493-encoded SMIM26, an understudied microprotein localized in mitochondria, is tendentiously downregulated in clear …
MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.
Li C, Han T, Li Q, Zhang M, Guo R, Yang Y, Lu W, Li Z, Peng C, Wu P, Tian X, Wang Q, Wang Y, Zhou V, Han Z, Li H, Wang F, Hu R. Li C, et al. Nucleic Acids Res. 2021 Apr 19;49(7):3796-3813. doi: 10.1093/nar/gkab155. Nucleic Acids Res. 2021. PMID: 33744966 Free PMC article.
Here we reported that the three members of PABPs, including PABPC1, PABPC3 and PABPC4, were identified as novel substrates for MKRN3, whose deletion or loss-of-function mutations were genetically associated with human central precocious puberty (CPP). ...
Here we reported that the three members of PABPs, including PABPC1, PABPC3 and PABPC4, were identified as novel substrates for MKRN3, …
A novel long non-coding RNA RP11-286H15.1 represses hepatocellular carcinoma progression by promoting ubiquitination of PABPC4.
Jiang X, Wang G, Liu Y, Mei C, Yao Y, Wu X, Chen X, Ma W, Li K, Zhang Z, Yuan Y. Jiang X, et al. Cancer Lett. 2021 Feb 28;499:109-121. doi: 10.1016/j.canlet.2020.11.038. Epub 2020 Nov 28. Cancer Lett. 2021. PMID: 33259899
Furthermore, we confirmed that RP11-286H15.1 (620-750 nucleotides) binds to poly(A) binding protein 4 (PABPC4) and promotes its ubiquitination, thus, reducing the stability of TRIM37 and CDC27 mRNAs. Our study demonstrates that a novel lncRNA, RP11-286H15.1, represses HCC …
Furthermore, we confirmed that RP11-286H15.1 (620-750 nucleotides) binds to poly(A) binding protein 4 (PABPC4) and promotes its ubiqu …
Assessing the Link between Diabetic Metabolic Dysregulation and Breast Cancer Progression.
Ahmed SBM, Radwan N, Amer S, Saheb Sharif-Askari N, Mahdami A, Samara KA, Halwani R, Jelinek HF. Ahmed SBM, et al. Int J Mol Sci. 2023 Jul 23;24(14):11816. doi: 10.3390/ijms241411816. Int J Mol Sci. 2023. PMID: 37511575 Free PMC article.
Diabetes mellitus is a burdensome disease that affects various cellular functions through altered glucose metabolism. Several reports have linked diabetes to cancer development; however, the exact molecular mechanism of how diabetes-related traits contribute to cancer …
Diabetes mellitus is a burdensome disease that affects various cellular functions through altered glucose metabolism. Several reports have l …
miR-192-5p Silencing by Genetic Aberrations Is a Key Event in Hepatocellular Carcinomas with Cancer Stem Cell Features.
Gu Y, Wei X, Sun Y, Gao H, Zheng X, Wong LL, Jin L, Liu N, Hernandez B, Peplowska K, Zhao X, Zhan QM, Feng XH, Tang ZY, Ji J. Gu Y, et al. Cancer Res. 2019 Mar 1;79(5):941-953. doi: 10.1158/0008-5472.CAN-18-1675. Epub 2018 Dec 7. Cancer Res. 2019. PMID: 30530815 Free PMC article.
Various cancer stem cell (CSC) biomarkers have been identified for hepatocellular carcinoma (HCC), but little is known about the implications of heterogeneity and shared molecular networks within the CSC population. ...This study reveals the circuit from hypermethylation o …
Various cancer stem cell (CSC) biomarkers have been identified for hepatocellular carcinoma (HCC), but little is known about the impl …
Immunohistochemical analysis of medullary breast carcinoma autoantigens in different histological types of breast carcinomas.
Kostianets O, Antoniuk S, Filonenko V, Kiyamova R. Kostianets O, et al. Diagn Pathol. 2012 Nov 26;7:161. doi: 10.1186/1746-1596-7-161. Diagn Pathol. 2012. PMID: 23181716 Free PMC article.
In current study we analyzed six previously identified medullary breast carcinoma autoantigens including LGALS3BP, RAD50, FAM50A, RBPJ, PABPC4, LRRFIP1 with cancer restricted serological profile in different histological types of breast cancer. ...The most si …
In current study we analyzed six previously identified medullary breast carcinoma autoantigens including LGALS3BP, RAD50, FAM50A, RBPJ, P …
Cytoplasmic poly(A) binding proteins regulate telomerase activity and cell growth in human papillomavirus type 16 E6-expressing keratinocytes.
Katzenellenbogen RA, Vliet-Gregg P, Xu M, Galloway DA. Katzenellenbogen RA, et al. J Virol. 2010 Dec;84(24):12934-44. doi: 10.1128/JVI.01377-10. Epub 2010 Oct 13. J Virol. 2010. PMID: 20943973 Free PMC article.
Although the amount and cellular localization of PABPCs were largely unchanged in cervical cancer cell lines with or without HPV16 and in human foreskin keratinocytes (HFKs) with or without HPV16 E6, knockdown of PABPCs decreased hTERT mRNA and telomerase activity and over …
Although the amount and cellular localization of PABPCs were largely unchanged in cervical cancer cell lines with or without HPV16 an …
17 results