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1985 1
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Page 1
Cancer testis antigen PASD1 expression and immunogenicity in human colorectal cancer and polyps.
Sukor NF, Yahaya A, Sagap I, Jamal R, Johdi NA. Sukor NF, et al. Turk J Biol. 2022 Jul 14;46(5):361-374. doi: 10.55730/1300-0152.2623. eCollection 2022. Turk J Biol. 2022. PMID: 37529004 Free PMC article.
Per ARNT Sim domain containing 1 (PASD1) is a cancer-testis antigen expressed in cancers including CRC but not in normal tissues except for normal testes. ...Both PASD1-1 and PASD1-2 proteins were expressed in 31.7% of CRC and 29.4% of polyps sa …
Per ARNT Sim domain containing 1 (PASD1) is a cancer-testis antigen expressed in cancers including CRC but not in norma …
Validation of immunogenic PASD1 peptides against HLA-A*24:02 colorectal cancer.
Soh JE, Abu N, Sagap I, Mazlan L, Yahaya A, Mustangin M, Khoo TS, Saidin S, Ishak M, Ab Mutalib NS, Jamal R. Soh JE, et al. Immunotherapy. 2019 Oct;11(14):1205-1219. doi: 10.2217/imt-2019-0073. Epub 2019 Sep 3. Immunotherapy. 2019. PMID: 31478431
We aimed to validate four PASD1 peptides as the immunotherapeutic targets in colorectal cancer. ...PASD1(4) peptide was shown to be immunogenic in colorectal cancer samples. ...
We aimed to validate four PASD1 peptides as the immunotherapeutic targets in colorectal cancer. ...PASD1(4) peptide was …
Cancer/Testis Antigen PASD1 Silences the Circadian Clock.
Michael AK, Harvey SL, Sammons PJ, Anderson AP, Kopalle HM, Banham AH, Partch CL. Michael AK, et al. Mol Cell. 2015 Jun 4;58(5):743-54. doi: 10.1016/j.molcel.2015.03.031. Epub 2015 Apr 30. Mol Cell. 2015. PMID: 25936801 Free PMC article.
Pathways driven by other bHLH-PAS transcription factors have a homologous repressor that modulates activity on a tissue-specific basis, but none have been identified for CLOCK:BMAL1. We show here that the cancer/testis antigen PASD1 fulfills this role to suppress ci …
Pathways driven by other bHLH-PAS transcription factors have a homologous repressor that modulates activity on a tissue-specific basis, but …
Infrequent Expression of the Cancer-Testis Antigen, PASD1, in Ovarian Cancer.
Khan G, Brooks SE, Mills KI, Guinn BA. Khan G, et al. Biomark Cancer. 2015 Aug 16;7:31-8. doi: 10.4137/BIC.S28378. eCollection 2015. Biomark Cancer. 2015. PMID: 26327782 Free PMC article.
Therefore, it is imperative that early-stage biomarkers are identified to enhance the early detection of ovarian cancer. Cancer-testis antigens (CTAs), such as Per ARNT SIM (PAS) domain containing 1 (PASD1), are unique in that their expression is restricted t …
Therefore, it is imperative that early-stage biomarkers are identified to enhance the early detection of ovarian cancer. Cancer …
DNA vaccines to target the cancer testis antigen PASD1 in human multiple myeloma.
Joseph-Pietras D, Gao Y, Zojer N, Ait-Tahar K, Banham AH, Pulford K, Rice J, Savelyeva N, Sahota SS. Joseph-Pietras D, et al. Leukemia. 2010 Nov;24(11):1951-9. doi: 10.1038/leu.2010.196. Epub 2010 Sep 23. Leukemia. 2010. PMID: 20861911
We previously described PASD1 as a new cancer testis antigen in multiple myeloma (MM) that is retained post-therapy, suggesting the use of vaccination strategies to induce anti-PASD1 immunity in a setting of minimal residual disease. ...DNA vaccines encoded t …
We previously described PASD1 as a new cancer testis antigen in multiple myeloma (MM) that is retained post-therapy, suggestin …
An analogue peptide from the Cancer/Testis antigen PASD1 induces CD8+ T cell responses against naturally processed peptide.
Hardwick N, Buchan S, Ingram W, Khan G, Vittes G, Rice J, Pulford K, Mufti G, Stevenson F, Guinn BA. Hardwick N, et al. Cancer Immun. 2013 Jul 15;13:16. Print 2013. Cancer Immun. 2013. PMID: 23882161 Free PMC article.
We have previously identified the novel Cancer/Testis antigen PASD1 by immunoscreening a testis library with pooled acute myeloid leukemia (AML) patient sera. ...In addition, peptide-specific T cells could be expanded from cancer patients by stimulation with …
We have previously identified the novel Cancer/Testis antigen PASD1 by immunoscreening a testis library with pooled acute myel …
PAS Domain Containing Repressor 1 (PASD1) Promotes Glioma Cell Proliferation Through Inhibiting Apoptosis In Vitro.
Li R, Guo M, Song L. Li R, et al. Med Sci Monit. 2019 Sep 16;25:6955-6964. doi: 10.12659/MSM.916308. Med Sci Monit. 2019. PMID: 31558691 Free PMC article.
BACKGROUND PAS domain containing repressor 1 (PASD1), the cancer-testis antigen (CTA), has been reported to be aberrantly expressed in various cancer tissues and cancer cell lines; however, normal PASD1 expression ca …
BACKGROUND PAS domain containing repressor 1 (PASD1), the cancer-testis antigen (CTA), has been r …
PASD1 promotes STAT3 activity and tumor growth by inhibiting TC45-mediated dephosphorylation of STAT3 in the nucleus.
Xu ZS, Zhang HX, Zhang YL, Liu TT, Ran Y, Chen LT, Wang YY, Shu HB. Xu ZS, et al. J Mol Cell Biol. 2016 Jun;8(3):221-31. doi: 10.1093/jmcb/mjw005. Epub 2016 Feb 17. J Mol Cell Biol. 2016. PMID: 26892021
Overexpression of PASD1 activated STAT3 and potentiated IL-6-induced activation of STAT3, whereas knockdown of PASD1 had opposite effects. Endogenous coimmunoprecipitation experiments indicated that PASD1 interacted with STAT3 in the nucleus. Overexpression o …
Overexpression of PASD1 activated STAT3 and potentiated IL-6-induced activation of STAT3, whereas knockdown of PASD1 had oppos …
Identification of Cancer/Testis Antigens Related to Gastric Cancer Prognosis Based on Co-Expression Network and Integrated Transcriptome Analyses.
Ansari S, Nikpour P. Ansari S, et al. Adv Biomed Res. 2023 Feb 25;12:52. doi: 10.4103/abr.abr_400_21. eCollection 2023. Adv Biomed Res. 2023. PMID: 37057240 Free PMC article.
BACKGROUND: Gastric cancer is a worldwide life-threatening cancer. The underlying cause of it is still unknown. We have noticed that some cancer/testis antigens (CTAs) are up-regulated in gastric cancer. ...
BACKGROUND: Gastric cancer is a worldwide life-threatening cancer. The underlying cause of it is still unknown. We have notice …
26 results