Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 2
1994 6
1995 2
1997 4
1998 11
1999 6
2000 12
2001 11
2002 8
2003 9
2004 6
2005 8
2006 13
2007 16
2008 15
2009 14
2010 22
2011 24
2012 25
2013 13
2014 31
2015 17
2016 22
2017 37
2018 38
2019 29
2020 28
2021 32
2022 34
2023 23
2024 7

Text availability

Article attribute

Article type

Publication date

Search Results

471 results

Results by year

Filters applied: . Clear all
Page 1
TNFRSF9 Suppressed the Progression of Breast Cancer via the p38MAPK/PAX6 Signaling Pathway.
Liu X, Zhou Y, Qin C, Zhu X. Liu X, et al. J Oncol. 2022 Jun 28;2022:8549781. doi: 10.1155/2022/8549781. eCollection 2022. J Oncol. 2022. PMID: 35799609 Free PMC article.
Moreover, we identify that downregulation of TNFRSF9 can upregulate the phosphorylated p38 (p-p38) and PAX6. We further elucidate that p-p38 is essential for PAX6 expression as p38 phosphorylation inhibitor can reverse the upregulation of PAX6 and suppress ce …
Moreover, we identify that downregulation of TNFRSF9 can upregulate the phosphorylated p38 (p-p38) and PAX6. We further elucidate tha …
Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma.
Ooki A, Dinalankara W, Marchionni L, Tsay JJ, Goparaju C, Maleki Z, Rom WN, Pass HI, Hoque MO. Ooki A, et al. Oncogene. 2018 Nov;37(45):5967-5981. doi: 10.1038/s41388-018-0373-2. Epub 2018 Jul 6. Oncogene. 2018. PMID: 29980786 Free PMC article.
It remains unclear whether PAX6 acts as a crucial transcription factor for lung cancer stem cell (CSC) traits. We demonstrate that PAX6 acts as an oncogene responsible for induction of cancer stemness properties in lung adenocarcinoma (LUAD). ...
It remains unclear whether PAX6 acts as a crucial transcription factor for lung cancer stem cell (CSC) traits. We demonstrate …
PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility.
Jing N, Du X, Liang Y, Tao Z, Bao S, Xiao H, Dong B, Gao WQ, Fang YX. Jing N, et al. J Exp Clin Cancer Res. 2024 May 15;43(1):144. doi: 10.1186/s13046-024-03064-1. J Exp Clin Cancer Res. 2024. PMID: 38745318 Free PMC article.
Importantly, loss of AR resulted in an enhanced expression of PAX6, which reprogramed the lineage plasticity of prostate cancer cells to develop NE phenotypes through the MET/STAT5A signaling pathway. Through ATAC-seq, we found that a high expression level of PAX …
Importantly, loss of AR resulted in an enhanced expression of PAX6, which reprogramed the lineage plasticity of prostate cancer …
Tumor suppressor PAX6 functions as androgen receptor co-repressor to inhibit prostate cancer growth.
Shyr CR, Tsai MY, Yeh S, Kang HY, Chang YC, Wong PL, Huang CC, Huang KE, Chang C. Shyr CR, et al. Prostate. 2010 Feb 1;70(2):190-9. doi: 10.1002/pros.21052. Prostate. 2010. PMID: 19790232 Free PMC article.
To determine the role of PAX6 in prostate cancer, we investigated whether PAX6 interacts with AR to affect prostate cancer development. ...RESULTS: In prostate cancer tissues, PAX6 expression was stronger in normal epithelial cells than …
To determine the role of PAX6 in prostate cancer, we investigated whether PAX6 interacts with AR to affect prostate …
Elevation of microRNA-365 impedes malignant behaviors of gastric cancer cells by inhibiting PAX6.
Hong D, Zang A, Wang Z, Yang L, Ren G, Zhang C, Zhang L, Hou W, Wei Y. Hong D, et al. Funct Integr Genomics. 2022 Oct;22(5):825-834. doi: 10.1007/s10142-022-00858-4. Epub 2022 Apr 28. Funct Integr Genomics. 2022. PMID: 35484308
MicroRNA-365 (miR-365) has been revealed to be a vital regulator in tumorigenesis of multiple cancers, while there is a large gap in the knowledge about miR-365 expression and gastric cancer (GC). ...The promoted miR-365 could repress oncogenicity in vivo and malign …
MicroRNA-365 (miR-365) has been revealed to be a vital regulator in tumorigenesis of multiple cancers, while there is a large gap in …
Translation of paired box 6 (PAX6) mRNA is IRES-mediated and inhibited by cymarin in breast cancer cells.
Li Q, Liu X, Xu Y, Lu Z, Jiang S, Yao Y. Li Q, et al. Genes Genet Syst. 2023 Oct 24;98(4):161-169. doi: 10.1266/ggs.23-00039. Epub 2023 Oct 4. Genes Genet Syst. 2023. PMID: 37793815 Free article.
Its expression is upregulated in many cancers including breast cancer, but the process of PAX6 mRNA translation has rarely been studied. ...These results provide novel insights into the translation mechanism of PAX6 in breast cancer cells and su …
Its expression is upregulated in many cancers including breast cancer, but the process of PAX6 mRNA translation has rar …
The Spectrum of PAX6 Mutations and Genotype-Phenotype Correlations in the Eye.
Lima Cunha D, Arno G, Corton M, Moosajee M. Lima Cunha D, et al. Genes (Basel). 2019 Dec 17;10(12):1050. doi: 10.3390/genes10121050. Genes (Basel). 2019. PMID: 31861090 Free PMC article. Review.
There are more than 500 different mutations described to affect PAX6 and its regulatory regions, the majority of which lead to PAX6 haploinsufficiency, causing several ocular and systemic abnormalities. ...This review will cover recent advancements in PAX6 re …
There are more than 500 different mutations described to affect PAX6 and its regulatory regions, the majority of which lead to PAX …
PAX6 overexpression is associated with the poor prognosis of invasive ductal breast cancer.
Xia X, Yin W, Zhang X, Yu X, Wang C, Xu S, Feng W, Yang H. Xia X, et al. Oncol Lett. 2015 Sep;10(3):1501-1506. doi: 10.3892/ol.2015.3434. Epub 2015 Jun 29. Oncol Lett. 2015. PMID: 26622698 Free PMC article.
Previous studies have suggested that the PAX6 promoter is hypermethylated in breast cancer and that it is involved in breast cancer cell proliferation. ...In conclusion, high tumor PAX6 staining intensity by IHC was associated with a poor prognosis in …
Previous studies have suggested that the PAX6 promoter is hypermethylated in breast cancer and that it is involved in breast …
471 results