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Pan-cancer analysis of oncogenic role of Programmed Cell Death 2 Like (PDCD2L) and validation in colorectal cancer.
Gao H, Xu C, Liang J, Ge S, Zhang F, Tuo Y, Shi H, Han A. Gao H, et al. Cancer Cell Int. 2022 Feb 25;22(1):100. doi: 10.1186/s12935-022-02525-x. Cancer Cell Int. 2022. PMID: 35216602 Free PMC article.
However, the role of PDCD2L in human cancers is unclear. METHODS: Multiple bioinformatic methods, in vitro function experiments and validation were performed to clarify the oncogenic role of PDCD2L in human cancers. ...CONCLUSIONS: Our study shows that …
However, the role of PDCD2L in human cancers is unclear. METHODS: Multiple bioinformatic methods, in vitro function experiment …
Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo.
Hao X, Fan H, Yang J, Tang J, Zhou J, Zhao Y, Huang L, Xia Y. Hao X, et al. J Nat Prod. 2022 Aug 26;85(8):2006-2017. doi: 10.1021/acs.jnatprod.2c00400. Epub 2022 Aug 17. J Nat Prod. 2022. PMID: 35976233 Review.
Bladder cancer, specifically, muscle-invasive bladder cancer (MIBC), is among the most common malignant tumors. ...Nodosin, found in Isodon serra (Maxim.) Kudo (known as Xihuangcao), may inhibit bladder cancer cells. Transcriptomics and proteomics dual-omic a …
Bladder cancer, specifically, muscle-invasive bladder cancer (MIBC), is among the most common malignant tumors. ...Nodosin, fo …
Weighted correlation network analysis revealed novel long non-coding RNAs for colorectal cancer.
Chodary Khameneh S, Razi S, Shamdani S, Uzan G, Naserian S. Chodary Khameneh S, et al. Sci Rep. 2022 Feb 22;12(1):2990. doi: 10.1038/s41598-022-06934-w. Sci Rep. 2022. PMID: 35194111 Free PMC article.
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide, which after breast, lung and, prostate cancers, is the fourth prevalent cancer in the United States. ...In the current study, publicly available microarray gene expression data of …
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide, which after breast, lung and, prostate cancers, …
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
Maguire SL, Peck B, Wai PT, Campbell J, Barker H, Gulati A, Daley F, Vyse S, Huang P, Lord CJ, Farnie G, Brennan K, Natrajan R. Maguire SL, et al. J Pathol. 2016 Nov;240(3):315-328. doi: 10.1002/path.4778. J Pathol. 2016. PMID: 27512948 Free PMC article.
Here, we sought to comprehensively characterise the genomic and transcriptomic features of the MCF10 isogenic model of breast cancer progression, and to functionally validate potential driver alterations in three-dimensional (3D) spheroids that may provide insights into br …
Here, we sought to comprehensively characterise the genomic and transcriptomic features of the MCF10 isogenic model of breast cancer …
Zebrafish Model for Functional Screening of Flow-Responsive Genes.
Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton JP, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJ, Evans PC. Serbanovic-Canic J, et al. Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):130-143. doi: 10.1161/ATVBAHA.116.308502. Epub 2016 Nov 10. Arterioscler Thromb Vasc Biol. 2017. PMID: 27834691 Free PMC article.
A phenotypic change was observed in 4 genes; p53-related protein (PERP) and programmed cell death 2-like protein functioned as positive regulators of apoptosis, whereas angiopoietin-like 4 and cadherin 13 were negative regulators. The regulation of perp, cdh13, angptl4, and pd …
A phenotypic change was observed in 4 genes; p53-related protein (PERP) and programmed cell death 2-like protein functioned as positive regu …
Cloning of cDNAs with PDCD2(C) domain and their expressions during apoptosis of HEK293T cells.
Chen Q, Qian K, Yan C. Chen Q, et al. Mol Cell Biochem. 2005 Dec;280(1-2):185-91. doi: 10.1007/s11010-005-8910-z. Mol Cell Biochem. 2005. PMID: 16311922
The RT-PCR products (AY948416, AY948417) of PDCD2 from RNA of human embryonic kidney 293T (HEK293T) and gastric cancer AGS cell line lost common 99 bp when compared with the sequences of NCBI database (NM_002598, NM_144781). ...
The RT-PCR products (AY948416, AY948417) of PDCD2 from RNA of human embryonic kidney 293T (HEK293T) and gastric cancer AGS cell line …