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Year Number of Results
2007 1
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Lower expression of PDZRN3 induces endometrial carcinoma progression via the activation of canonical Wnt signaling.
Li Q, Zhong J, Yang S, Liang Y. Li Q, et al. Oncol Lett. 2022 Mar;23(3):98. doi: 10.3892/ol.2022.13218. Epub 2022 Jan 27. Oncol Lett. 2022. PMID: 35154429 Free PMC article.
Endometrial carcinoma (EC) exhibits an extremely malignant biological behavior and has a high mortality rate. EC has recently become one of the most lethal cancers in women worldwide. E3 ubiquitin ligases play an important role in the biological function of healthy cells b …
Endometrial carcinoma (EC) exhibits an extremely malignant biological behavior and has a high mortality rate. EC has recently become one of …
Functional New Transcription Factors (TFs) Associated with Cervical Cancer.
Jiang Y, Chen S. Jiang Y, et al. J Healthc Eng. 2022 Jan 25;2022:8381559. doi: 10.1155/2022/8381559. eCollection 2022. J Healthc Eng. 2022. PMID: 35126951 Free PMC article. Retracted.
The Gene Expression Omnibus (GEO) database was utilized to analyze ten cervical cancer datasets using the Robust Rank Aggregation (RRA) technique. ...Our research has revealed evidence that EMX2 acted as a tumor suppressor in cervical cancer and PDZRN3 might …
The Gene Expression Omnibus (GEO) database was utilized to analyze ten cervical cancer datasets using the Robust Rank Aggregation (RR …
TBX20 inhibits colorectal cancer tumorigenesis by impairing NHEJ-mediated DNA repair.
Luo J, Chen JW, Zhou J, Han K, Li S, Duan JL, Cao CH, Lin JL, Xie D, Wang FW. Luo J, et al. Cancer Sci. 2022 Jun;113(6):2008-2021. doi: 10.1111/cas.15348. Epub 2022 Apr 13. Cancer Sci. 2022. PMID: 35348274 Free PMC article.
Here, we demonstrated that TBX20, a T-box TF family protein, was downregulated with hypermethylation of promoter in early-stage CRC tissues and correlated with a poor prognosis for CRC patients. Moreover, we identified PDZRN3 as the E3 ubiquitin ligase of TBX20 protein, wh …
Here, we demonstrated that TBX20, a T-box TF family protein, was downregulated with hypermethylation of promoter in early-stage CRC tissues …
Differential expression and analysis of extrachromosomal circular DNAs as serum biomarkers in lung adenocarcinoma.
Xu G, Shi W, Ling L, Li C, Shao F, Chen J, Wang Y. Xu G, et al. J Clin Lab Anal. 2022 Jun;36(6):e24425. doi: 10.1002/jcla.24425. Epub 2022 Apr 20. J Clin Lab Anal. 2022. PMID: 35441736 Free PMC article.
However, there are limited reports on differential eccDNA expression and analysis in lung cancer, especially in lung adenocarcinoma (LAD). METHODS: Three LAD and three corresponding NT tissues samples were used for eccDNA next-generation sequencing analysis, and an additio …
However, there are limited reports on differential eccDNA expression and analysis in lung cancer, especially in lung adenocarcinoma ( …
Identification Invasion-Related Long Non-Coding RNAs in Lung Adenocarcinoma and Analysis of Competitive Endogenous RNA Regulatory Networks.
Mao Y, Cai F, Jiang T, Zhu X. Mao Y, et al. Int J Gen Med. 2023 May 15;16:1817-1831. doi: 10.2147/IJGM.S407266. eCollection 2023. Int J Gen Med. 2023. PMID: 37213476 Free PMC article.
BACKGROUND: Cell invasion plays a vital role in cancer development and progression. Aberrant expression of long non-coding RNAs (lncRNAs) is also critical in carcinogenesis. ...RESULTS: A total of 45 DElncRNAs were identified as DEIRLs. RP3-525N10.2, LINC00857, EP300-AS1, …
BACKGROUND: Cell invasion plays a vital role in cancer development and progression. Aberrant expression of long non-coding RNAs (lncR …
Dichotomy of Genetic Abnormalities in PEComas With Therapeutic Implications.
Agaram NP, Sung YS, Zhang L, Chen CL, Chen HW, Singer S, Dickson MA, Berger MF, Antonescu CR. Agaram NP, et al. Am J Surg Pathol. 2015 Jun;39(6):813-25. doi: 10.1097/PAS.0000000000000389. Am J Surg Pathol. 2015. PMID: 25651471 Free PMC article.
Perivascular epithelioid cell neoplasms (PEComa) are a family of rare mesenchymal tumors with hybrid myo-melanocytic differentiation. ...In addition, novel RAD51B gene rearrangements were identified in 3 (8%) uterine PEComas, which showed a complex fusion pattern and were …
Perivascular epithelioid cell neoplasms (PEComa) are a family of rare mesenchymal tumors with hybrid myo-melanocytic differentiation. …
Copy-number variants in patients with a strong family history of pancreatic cancer.
Lucito R, Suresh S, Walter K, Pandey A, Lakshmi B, Krasnitz A, Sebat J, Wigler M, Klein AP, Brune K, Palmisano E, Maitra A, Goggins M, Hruban RH. Lucito R, et al. Cancer Biol Ther. 2007 Oct;6(10):1592-9. doi: 10.4161/cbt.6.10.4725. Epub 2007 Jul 12. Cancer Biol Ther. 2007. PMID: 17912030
We used representational oligonucleotide microarray analysis (ROMA) to characterize germ-line copy number variants in 60 cancer patients from 57 familial pancreatic cancer kindreds. Fifty-seven of the 60 patients had pancreatic cancer and three had nonpancrea …
We used representational oligonucleotide microarray analysis (ROMA) to characterize germ-line copy number variants in 60 cancer patie …
A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung cancer.
Han JY, Shin ES, Lee YS, Ghang HY, Kim SY, Hwang JA, Kim JY, Lee JS. Han JY, et al. Pharmacogenomics J. 2013 Oct;13(5):417-22. doi: 10.1038/tpj.2012.24. Epub 2012 Jun 5. Pharmacogenomics J. 2013. PMID: 22664479
We conducted the first genome-wide association study (GWAS) to search for novel susceptibility genes for irinotecan-related severe toxicities, such as diarrhea and neutropenia, in non-small-cell lung cancer (NSCLC) patients treated with irinotecan chemotherapy. The GWAS pu …
We conducted the first genome-wide association study (GWAS) to search for novel susceptibility genes for irinotecan-related severe toxicitie …
RAF1 rearrangements are common in pancreatic acinar cell carcinomas.
Prall OWJ, Nastevski V, Xu H, McEvoy CRE, Vissers JHA, Byrne DJ, Takano E, Yerneni S, Ellis S, Green T, Mitchell CA, Murray WK, Scott CL, Grimmond SM, Hofmann O, Papenfuss A, Kee D, Fellowes A, Brown IS, Miller G, Kumarasinghe MP, Perren A, Nahm CB, Mittal A, Samra J, Ahadi M, Fox SB, Chou A, Gill AJ. Prall OWJ, et al. Mod Pathol. 2020 Sep;33(9):1811-1821. doi: 10.1038/s41379-020-0545-9. Mod Pathol. 2020. PMID: 32358589 Free article.
RAF1 rearrangements were identified in 5 cases and confirmed by DNA and RNA sequencing to represent oncogenic fusions (GATM-RAF1, GOLGA4-RAF1, PDZRN3-RAF1, HERPUD1-RAF1 and TRIM33-RAF1) and to be mutually exclusive with BRAF and RET fusions, as well as KRAS mutations. ...
RAF1 rearrangements were identified in 5 cases and confirmed by DNA and RNA sequencing to represent oncogenic fusions (GATM-RAF1, GOLGA4-RAF …
12 results