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The following terms were not found in PubMed: 1476800ORlysophospholipase, putativeANDPlasmodium
Page 1
Identification and characterization of DNA endonucleases in Plasmodium falciparum 3D7 clone.
Jiang N, Tu Z, Zhang Y, Li J, Feng Y, Yang N, Sang X, Chen Q. Jiang N, et al. Malar J. 2018 Jun 18;17(1):232. doi: 10.1186/s12936-018-2388-0. Malar J. 2018. PMID: 29914511 Free PMC article.
But the proteins encoded by PF3D7_0305600 and PF3D7_1363500 were distributed around the infected erythrocyte membrane. ...Further, divalent irons did not show any specific enhancement on the activity of GST-PF3D7_1238600, but the activity of GST-PF3D7_ …
But the proteins encoded by PF3D7_0305600 and PF3D7_1363500 were distributed around the infected erythrocyte membrane. ...Furt …
The var3 genes of Plasmodium falciparum 3D7 strain are differentially expressed in infected erythrocytes.
Zhang Y, Jiang N, Chang Z, Wang H, Lu H, Wahlgren M, Chen Q. Zhang Y, et al. Parasite. 2014;21:19. doi: 10.1051/parasite/2014019. Epub 2014 Apr 24. Parasite. 2014. PMID: 24759654 Free PMC article.
Previous studies have been mainly focused on the typical var genes, while the biological characteristics of the var3 genes remain unknown. In this study, the three var3 genes, PF3D7_0100300, PF3D7_0600400, and PF3D7_0937600, were found to be transcribed in th …
Previous studies have been mainly focused on the typical var genes, while the biological characteristics of the var3 genes remain unknown. I …
The structure of Plasmodium falciparum 3D7_0606800 reveals a bi-lobed architecture that supports re-annotation as a Venus Flytrap protein.
Parker ML, Ramaswamy R, van Gordon K, Powell CJ, Bosch J, Boulanger MJ. Parker ML, et al. Protein Sci. 2017 Sep;26(9):1878-1885. doi: 10.1002/pro.3218. Epub 2017 Jul 26. Protein Sci. 2017. PMID: 28681555 Free PMC article.
Of these, Pf3D7_0606800 is highly immunogenic and has been designated a potential top 10 candidate for inclusion in a multicomponent malarial vaccine. ...Towards elucidating Pf3D7_0606800 function, we determined its structure to a resolution of 2.35 A using selenium …
Of these, Pf3D7_0606800 is highly immunogenic and has been designated a potential top 10 candidate for inclusion in a multicomponent …
Characterization of Plasmodium falciparum prohibitins as novel targets to block infection in humans by impairing the growth and transmission of the parasite.
Saini M, Ngwa CJ, Marothia M, Verma P, Ahmad S, Kumari J, Anand S, Vandana V, Goyal B, Chakraborti S, Pandey KC, Garg S, Pati S, Ranganathan A, Pradel G, Singh S. Saini M, et al. Biochem Pharmacol. 2023 Jun;212:115567. doi: 10.1016/j.bcp.2023.115567. Epub 2023 Apr 22. Biochem Pharmacol. 2023. PMID: 37088154
Here, we characterize PHBs encoding putative genes ofPlasmodium falciparum by exploiting different orthologous models. We demonstrated that PfPHB1 (PF3D7_0829200) and PfPHB2 (PF3D7_1014700) are expressed in asexual and sexual blood stages of the parasite. ... …
Here, we characterize PHBs encoding putative genes ofPlasmodium falciparum by exploiting different orthologous models. We demonstrate …
Haematological response in experimental human Plasmodium falciparum and Plasmodium vivax malaria.
Woolley SD, Marquart L, Woodford J, Chalon S, Moehrle JJ, McCarthy JS, Barber BE. Woolley SD, et al. Malar J. 2021 Dec 20;20(1):470. doi: 10.1186/s12936-021-04003-7. Malar J. 2021. PMID: 34930260 Free PMC article.
Induced blood stage malaria volunteer infection studies (IBSM-VIS) provide a unique opportunity to evaluate the haematological response to early Plasmodium falciparum and Plasmodium vivax infection. METHODS: This study was an analysis of the haemoglobin, red cell counts, a …
Induced blood stage malaria volunteer infection studies (IBSM-VIS) provide a unique opportunity to evaluate the haematological response to e …
Constituents from ripe figs of Ficus vallis-choudae Delile (Moraceae) with antiplasmodial activity.
Chouna HSD, Dize D, Kagho DUK, Bankeu JJK, Fongang YSF, Tali MBT, Ponou BK, Bitchagno GTM, Awantu AF, Tapondjou LA, Lenta BN, Fekam FB, Sewald N, Ngouela SA. Chouna HSD, et al. Parasitol Res. 2022 Jul;121(7):2121-2127. doi: 10.1007/s00436-022-07540-5. Epub 2022 May 17. Parasitol Res. 2022. PMID: 35578036 Free PMC article.
Some of the isolated compounds were assessed in vitro for their antiplasmodial activity against Plasmodium falciparum chloroquine-sensitive 3D7 (Pf3D7) and multidrug-resistant Dd2 strains. ...Among the tested compounds, wighteone (2) was the most active again …
Some of the isolated compounds were assessed in vitro for their antiplasmodial activity against Plasmodium falciparum chloroquine-sen …
Specific sub fractions from Terminalia mantaly (H. Perrier) extracts potently inhibit Plasmodium falciparum rings, merozoite egress and invasion.
Jiatsa Mbouna CD, Tchatat Tali BM, Tsouh Fokou PV, Madiesse Kemgne EA, Keumoe R, Toghueo Kouipou RM, Yamthe Tchokouaha LR, Tchuente Tchuenmogne MA, Kenou DK, Sahal D, Boyom FF. Jiatsa Mbouna CD, et al. J Ethnopharmacol. 2022 Mar 1;285:114909. doi: 10.1016/j.jep.2021.114909. Epub 2021 Dec 10. J Ethnopharmacol. 2022. PMID: 34902534
The SFs were tested against Plasmodium falciparum 3D7 (Pf3D7-chloroquine sensitive) and INDO (PfINDO-chloroquine resistant) strains in culture. ...Sub fraction Tm36 (IC(50)PfINDO: 0.41 mug/mL, SI(PfINDO) > 243; IC(50)Pf3D7: 0.29 mug/mL, SI(Pf3D7 …
The SFs were tested against Plasmodium falciparum 3D7 (Pf3D7-chloroquine sensitive) and INDO (PfINDO-chloroquine resist …
Detection of Developmental Asexual Stage-Specific RNA Editing Events in Plasmodium falciparum 3D7 Malaria Parasite.
Azad MTA, Sugi T, Qulsum U, Kato K. Azad MTA, et al. Microorganisms. 2024 Jan 10;12(1):137. doi: 10.3390/microorganisms12010137. Microorganisms. 2024. PMID: 38257964 Free PMC article.
We investigated developmental stage-specific RNA editing in selected genes in Plasmodium falciparum 3D7. We detected extensive amination- and deamination-type RNA editing at 8, 16, 24, 32, 40, and 46 h in tightly synchronized Plasmodium. ...In 28S, rRNA editing conv …
We investigated developmental stage-specific RNA editing in selected genes in Plasmodium falciparum 3D7. We detected extensive …
Specialized antiplasmodial secondary metabolites from Aspergillus niger 58, an endophytic fungus from Terminalia catappa.
Kouipou Toghueo RM, Kemgne EAM, Sahal D, Yadav M, Kenou Kagho DU, Yang B, Baker BJ, Boyom FF. Kouipou Toghueo RM, et al. J Ethnopharmacol. 2021 Apr 6;269:113672. doi: 10.1016/j.jep.2020.113672. Epub 2020 Dec 7. J Ethnopharmacol. 2021. PMID: 33301916
RESULTS: The results revealed that the multidimensional purification of the crude extract (IC(50): 4.03 mug/mL) provided RPHPLC F17 (IC(50): 0.09 mug/mL) and RPHPLC F18 (IC(50): 0.1 mug/mL) with activity against P. falciparum 3D7 (Pf3D7) strain. Moreover, bot …
RESULTS: The results revealed that the multidimensional purification of the crude extract (IC(50): 4.03 mug/mL) provided RPHPLC F17 (IC(50): …
Repositioning: the fast track to new anti-malarial medicines?
Lotharius J, Gamo-Benito FJ, Angulo-Barturen I, Clark J, Connelly M, Ferrer-Bazaga S, Parkinson T, Viswanath P, Bandodkar B, Rautela N, Bharath S, Duffy S, Avery VM, Möhrle JJ, Guy RK, Wells T. Lotharius J, et al. Malar J. 2014 Apr 14;13:143. doi: 10.1186/1475-2875-13-143. Malar J. 2014. PMID: 24731288 Free PMC article.
The compound libraries of GlaxoSmithKline (GSK), Pfizer and AstraZeneca (AZ) comprising drugs that have undergone clinical studies in other therapeutic areas, but not achieved approval, and a set of US Food and Drug Administration (FDA)-approved drugs and other bio-actives were t …
The compound libraries of GlaxoSmithKline (GSK), Pfizer and AstraZeneca (AZ) comprising drugs that have undergone clinical studies in other …
53 results