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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
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2002 1
2005 1
2006 1
2007 1
2013 1
2015 2
2016 1
2017 2
2018 1
2019 4
2020 1
2021 2
2022 2
2023 3
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23 results

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Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals.
Zhang H, Xie T, Shui Y, Qi Y. Zhang H, et al. Mol Med Rep. 2020 Jan;21(1):420-428. doi: 10.3892/mmr.2019.10798. Epub 2019 Nov 6. Mol Med Rep. 2020. PMID: 31746389
The expression of PLCB2 mRNA in various cancer lines was analyzed by reverse transcription-polymerase chain reaction (RT-PCR). ...Thus, PLCB2 may utilized as a potential therapeutic target in patients with melanoma....
The expression of PLCB2 mRNA in various cancer lines was analyzed by reverse transcription-polymerase chain reaction (RT-PCR). …
PLCβ2 Promotes VEGF-Induced Vascular Permeability.
Phoenix KN, Yue Z, Yue L, Cronin CG, Liang BT, Hoeppner LH, Claffey KP. Phoenix KN, et al. Arterioscler Thromb Vasc Biol. 2022 Oct;42(10):1229-1241. doi: 10.1161/ATVBAHA.122.317645. Epub 2022 Jul 21. Arterioscler Thromb Vasc Biol. 2022. PMID: 35861069 Free PMC article.
VEGF (vascular endothelial growth factor) is a key stimulus of vascular permeability in acute and chronic diseases including ischemia reperfusion injury, sepsis, and cancer. Identification of novel regulators of vascular permeability would allow for the development of effe …
VEGF (vascular endothelial growth factor) is a key stimulus of vascular permeability in acute and chronic diseases including ischemia reperf …
Diagnostic and prognostic value of mRNA expression of phospholipase C β family genes in hepatitis B virus‑associated hepatocellular carcinoma.
Wang X, Huang K, Zeng X, Liu Z, Liao X, Yang C, Yu T, Han C, Zhu G, Qin W, Peng T. Wang X, et al. Oncol Rep. 2019 May;41(5):2855-2875. doi: 10.3892/or.2019.7066. Epub 2019 Mar 14. Oncol Rep. 2019. PMID: 30896816 Free PMC article.
Four phospholipase C beta (PLCB) isoforms, PLCB1, PLCB2, PLCB3 and PLCB4, have been previously investigated regarding their roles in the metabolism of inositol lipids and cancer. ...PLCB1 and PLCB2 exhibited diagnostic value for HCC and their combination had …
Four phospholipase C beta (PLCB) isoforms, PLCB1, PLCB2, PLCB3 and PLCB4, have been previously investigated regarding their roles in …
Differentially expressed genes in metastatic advanced Egyptian bladder cancer.
Zekri AR, Hassan ZK, Bahnassy AA, Khaled HM, El-Rouby MN, Haggag RM, Abu-Taleb FM. Zekri AR, et al. Asian Pac J Cancer Prev. 2015;16(8):3543-9. doi: 10.7314/apjcp.2015.16.8.3543. Asian Pac J Cancer Prev. 2015. PMID: 25921176 Free article.
BACKGROUND: Bladder cancer is one of the most common cancers worldwide. Gene expression profiling using microarray technologies improves the understanding of cancer biology. The aim of this study was to determine the gene expression profile in Egyptian bladde …
BACKGROUND: Bladder cancer is one of the most common cancers worldwide. Gene expression profiling using microarray technologie …
Chemical profiling and investigation of molecular mechanisms underlying anti-hepatocellular carcinoma activity of extracts from Polygonum perfoliatum L.
Tang X, Liu L, Li Y, Hao S, Zhao Y, Wu X, Li M, Chen Y, Deng S, Gou S, Cai D, Chen M, Li X, Sun Y, Gu L, Li W, Wang F, Zhang Z, Yao L, Shen J, Xiao Z, Du F. Tang X, et al. Biomed Pharmacother. 2023 Oct;166:115315. doi: 10.1016/j.biopha.2023.115315. Epub 2023 Aug 12. Biomed Pharmacother. 2023. PMID: 37579693 Free article.
Numerous studies suggest that P. perfoliatum extract elicits significant anti-tumor, anti-inflammatory, anti-bacterial, and anti-viral effects. Nevertheless, the underlying mechanisms of its anti-liver cancer effects remain poorly understood. Our study suggests that P. per …
Numerous studies suggest that P. perfoliatum extract elicits significant anti-tumor, anti-inflammatory, anti-bacterial, and anti-viral effec …
Tracking footprints of artificial and natural selection signatures in breeding and non-breeding cats.
Zhang X, Jamwal K, Distl O. Zhang X, et al. Sci Rep. 2022 Oct 27;12(1):18061. doi: 10.1038/s41598-022-22155-7. Sci Rep. 2022. PMID: 36302822 Free PMC article.
Genes in these regions have previously been associated with reproduction (BUB1B), motor/neurological behavior (GPHN, GABRB3), cold-induced thermogenesis (DIO2, TSHR), immune system development (TSHR), viral carcinogenesis (GTF2A1), host immune response against bacteria, viruses, …
Genes in these regions have previously been associated with reproduction (BUB1B), motor/neurological behavior (GPHN, GABRB3), cold-induced t …
Identification of genes and pathways associated with MDR in MCF-7/MDR breast cancer cells by RNA-seq analysis.
Yang M, Li H, Li Y, Ruan Y, Quan C. Yang M, et al. Mol Med Rep. 2018 May;17(5):6211-6226. doi: 10.3892/mmr.2018.8704. Epub 2018 Mar 7. Mol Med Rep. 2018. PMID: 29512753 Free PMC article.
Multidrug resistance (MDR) is a major problem in the treatment of breast cancer. In the present study, next-generation sequencing technology was employed to identify differentially expressed genes in MCF-7/MDR cells and MCF-7 cells, and aimed to investigate the underlying …
Multidrug resistance (MDR) is a major problem in the treatment of breast cancer. In the present study, next-generation sequencing tec …
Distinct Prognostic Values of Phospholipase C Beta Family Members for Non-Small Cell Lung Carcinoma.
Zhang T, Song X, Liao X, Wang X, Zhu G, Yang C, Xie X. Zhang T, et al. Biomed Res Int. 2019 Apr 7;2019:4256524. doi: 10.1155/2019/4256524. eCollection 2019. Biomed Res Int. 2019. PMID: 31080817 Free PMC article.
BACKGROUND: Non-small cell lung cancer (NSCLC) is a main cause of cancer-related mortality worldwide. The relationships of the phospholipase C beta (PLCB) enzymes, which are encoded by the genes PLCB1, PLCB2, PLCB3, and PLCB4, with NSCLC have not been investi …
BACKGROUND: Non-small cell lung cancer (NSCLC) is a main cause of cancer-related mortality worldwide. The relationships of the …
Identification of Metabolic-Associated Genes for the Prediction of Colon and Rectal Adenocarcinoma.
Cui Y, Han B, Zhang H, Liu H, Zhang F, Niu R. Cui Y, et al. Onco Targets Ther. 2021 Mar 31;14:2259-2277. doi: 10.2147/OTT.S297134. eCollection 2021. Onco Targets Ther. 2021. PMID: 33833525 Free PMC article.
METHODS: We first acquired the gene expression profiles of COAD and READ from the TCGA database, and then utilized univariate Cox analysis, Lasso regression, and multivariable Cox analysis to identify the MRGs for risk models. RESULTS: Eight genes (CPT1C, PLCB2, PLA2G2D, G …
METHODS: We first acquired the gene expression profiles of COAD and READ from the TCGA database, and then utilized univariate Cox analysis, …
Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in RETM918T Tumors.
Mancikova V, Montero-Conde C, Perales-Paton J, Fernandez A, Santacana M, Jodkowska K, Inglada-Pérez L, Castelblanco E, Borrego S, Encinas M, Matias-Guiu X, Fraga M, Robledo M. Mancikova V, et al. Clin Cancer Res. 2017 Mar 1;23(5):1334-1345. doi: 10.1158/1078-0432.CCR-16-0947. Epub 2016 Sep 12. Clin Cancer Res. 2017. PMID: 27620278 Free article.
Integration of methylation data with mRNA and miRNA expression data identified genes negatively regulated by promoter methylation. These in silico findings were confirmed in vitro for PLCB2, DKK4, MMP20, and miR-10a, -30a, and -200c. The mutation-specific aberrant methylat …
Integration of methylation data with mRNA and miRNA expression data identified genes negatively regulated by promoter methylation. These in …
23 results