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Year Number of Results
2008 2
2009 1
2010 3
2011 5
2012 7
2013 19
2014 23
2015 11
2016 8
2017 11
2018 9
2019 13
2020 10
2021 8
2022 8
2023 4
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126 results

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Page 1
PLCE1 Promotes Esophageal Cancer Cell Progression by Maintaining the Transcriptional Activity of Snail.
Zhai S, Liu C, Zhang L, Zhu J, Guo J, Zhang J, Chen Z, Zhou W, Chang T, Xu S, Qi Y, Zhuang T, Yu N, Wang W, Wang H, Yu S, Li X. Zhai S, et al. Neoplasia. 2017 Mar;19(3):154-164. doi: 10.1016/j.neo.2016.12.007. Epub 2017 Jan 29. Neoplasia. 2017. PMID: 28147304 Free PMC article.
However, the causative role of PLCE1 in esophageal cancer is not clear. We inactivated the functional alleles of PLCE1 by CRISPR/Cas9 genome editing technology. ...Therefore, our functional experiments showed the essential roles of PLCE1 in esophageal …
However, the causative role of PLCE1 in esophageal cancer is not clear. We inactivated the functional alleles of PLCE1 …
Prognostic value of PLCE1 expression in upper gastrointestinal cancer: a systematic review and meta-analysis.
Cui XB, Peng H, Li S, Li TT, Liu CX, Zhang SM, Jin TT, Hu JM, Jiang JF, Liang WH, Li N, Li L, Chen YZ, Li F. Cui XB, et al. Asian Pac J Cancer Prev. 2014;15(22):9661-6. doi: 10.7314/apjcp.2014.15.22.9661. Asian Pac J Cancer Prev. 2014. PMID: 25520085 Free article. Review.
However, the results of PLCE1 expression in esophageal and gastric cancer remain inconsistent and controversial. ...RESULTS: Seven articles were identified, including 761 esophageal and gastric cancer cases and 457 controls. Overall, we determined that PLC …
However, the results of PLCE1 expression in esophageal and gastric cancer remain inconsistent and controversial. ...RESULTS: S …
PLCE1 Polymorphisms Are Associated With Gastric Cancer Risk: The Changes in Protein Spatial Structure May Play a Potential Role.
Hu X, Jia J, Yang Z, Chen S, Xue J, Duan S, Yang P, Peng S, Yang L, Yuan L, Bao G. Hu X, et al. Front Genet. 2021 Aug 31;12:714915. doi: 10.3389/fgene.2021.714915. eCollection 2021. Front Genet. 2021. PMID: 34531897 Free PMC article.
BACKGROUND: Gastric cancer (GC) is one of the most significant health problems worldwide. ...The prognostic value of PLCE1 in GC was evaluated by the Kaplan-Meier plotter. To explored the potential functions of PLCE1, various bioinformatics analyses were cond …
BACKGROUND: Gastric cancer (GC) is one of the most significant health problems worldwide. ...The prognostic value of PLCE1 in …
Association between PLCE1 rs2274223 A > G polymorphism and cancer risk: proof from a meta-analysis.
Xue W, Zhu M, Wang Y, He J, Zheng L. Xue W, et al. Sci Rep. 2015 Jan 23;5:7986. doi: 10.1038/srep07986. Sci Rep. 2015. PMID: 25614244 Free PMC article. Review.
An increasing number of individual studies have investigated the association between PLCE1 rs2274223 polymorphism and cancer risk, but the conclusions are inconclusive. ...This meta-analysis demonstrated that PLCE1 rs2274223 A > G polymorphism may be assoc …
An increasing number of individual studies have investigated the association between PLCE1 rs2274223 polymorphism and cancer r …
[Association of GSTP1 and PLCE1 gene polymorphisms with primary esophageal cancer].
Han W, Li W, He Z. Han W, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2022 Nov 10;39(11):1283-1289. doi: 10.3760/cma.j.cn511374-20220330-00213. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2022. PMID: 36317220 Chinese.
Conditional Logistic regression analysis showed that smoking, family history of esophageal cancer and GG genotype at the rs2274223 locus of PLCE1 gene were the risk factors for esophageal cancer (P<0.05), and AG/GG genotypes at the A105G locus of GSTP1 gen …
Conditional Logistic regression analysis showed that smoking, family history of esophageal cancer and GG genotype at the rs2274223 lo …
Correlation between PLCE1 rs2274223 variant and digestive tract cancer: A meta-analysis.
Chen Q, Wang Y, Xu Y, Lin H, Xue F, Chen X. Chen Q, et al. Mol Genet Genomic Med. 2019 Apr;7(4):e00589. doi: 10.1002/mgg3.589. Epub 2019 Feb 19. Mol Genet Genomic Med. 2019. PMID: 30784231 Free PMC article.
BACKGROUND: The relationship between phospholipase C epsilon-1 (PLCE1) rs2274223 variant and digestive tract cancer remains inconclusive despite extensive investigations. ...However, no positive results were detected in Caucasians and West Asians. CONCLUSION: Our fi …
BACKGROUND: The relationship between phospholipase C epsilon-1 (PLCE1) rs2274223 variant and digestive tract cancer remains in …
PLCE1 inhibits apoptosis of non-small cell lung cancer via promoting PTEN methylation.
Yue QY, Zhao W, Tan Y, Deng XL, Zhang YH. Yue QY, et al. Eur Rev Med Pharmacol Sci. 2019 Jul;23(14):6211-6216. doi: 10.26355/eurrev_201907_18438. Eur Rev Med Pharmacol Sci. 2019. PMID: 31364122 Free article.
OBJECTIVE: To explore the role of phospholipase C epsilon 1 (PLCE1) in regulating cell apoptosis of non-small cell lung cancer (NSCLC) and its underlying mechanism. ...Transfection of PLCE1 siRNA in NSCLC cells remarkably induced cell apoptosis. CONCLUSIONS: …
OBJECTIVE: To explore the role of phospholipase C epsilon 1 (PLCE1) in regulating cell apoptosis of non-small cell lung cancer …
Single Nucleotide Polymorphisms in PLCE1 for Cancer Risk of Different Types: A Meta-Analysis.
Li X, Li X, Jiang M, Tian W, Zhou B. Li X, et al. Front Oncol. 2018 Dec 11;8:613. doi: 10.3389/fonc.2018.00613. eCollection 2018. Front Oncol. 2018. PMID: 30619753 Free PMC article.
Background: Recent studies have investigated the relationships between PLCE1 polymorphisms and cancer susceptibility. However, some findings lack consistency. ...Conclusions: Results of the current meta-analysis suggested that PLCE1 (rs2274223, rs3765524) pol …
Background: Recent studies have investigated the relationships between PLCE1 polymorphisms and cancer susceptibility. However, …
PLCE1 gene in esophageal cancer and interaction with environmental factors.
Guo LY, Zhang S, Suo Z, Yang CS, Zhao X, Zhang GA, Hu D, Ji XZ, Zhai M. Guo LY, et al. Asian Pac J Cancer Prev. 2015;16(7):2745-9. doi: 10.7314/apjcp.2015.16.7.2745. Asian Pac J Cancer Prev. 2015. PMID: 25854357 Free article.
OBJECTIVE: To study the PLCE1 gene rs2274223 polymorphism with regard to esophageal cancer and its interaction with diet, lifestyle, psychological and environmental factors in Southwest Shandong province. ...There was no statistically significant difference in TS sc …
OBJECTIVE: To study the PLCE1 gene rs2274223 polymorphism with regard to esophageal cancer and its interaction with diet, life …
PLCE1 Polymorphisms and Risk of Esophageal and Gastric Cancer in a Northwestern Chinese Population.
Liang P, Zhang W, Wang W, Dai P, Wang Q, Yan W, Wang W, Lei X, Cui D, Yan Z. Liang P, et al. Biomed Res Int. 2019 Feb 25;2019:9765191. doi: 10.1155/2019/9765191. eCollection 2019. Biomed Res Int. 2019. PMID: 30931333 Free PMC article.
The reported risk susceptibility between phospholipase C epsilon 1 (PLCE1) polymorphisms and esophageal cancer (EC) and gastric cancer (GC) remained inconsistent and controversial, especially on variants other than rs2274223. The relationship between PLCE1 …
The reported risk susceptibility between phospholipase C epsilon 1 (PLCE1) polymorphisms and esophageal cancer (EC) and gastri …
126 results