Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1969 1
1974 1
1975 5
1976 1
1977 2
1978 2
1979 1
1980 2
1981 2
1982 2
1983 5
1984 6
1985 2
1986 4
1987 2
1988 5
1989 3
1990 4
1991 8
1992 28
1993 44
1994 65
1995 70
1996 81
1997 77
1998 89
1999 87
2000 118
2001 106
2002 117
2003 128
2004 128
2005 123
2006 125
2007 141
2008 138
2009 127
2010 157
2011 161
2012 161
2013 162
2014 167
2015 137
2016 129
2017 137
2018 140
2019 141
2020 151
2021 148
2022 144
2023 121
2024 55

Text availability

Article attribute

Article type

Publication date

Search Results

3,626 results

Results by year

Filters applied: . Clear all
Page 1
PML Nuclear bodies: the cancer connection and beyond.
Abou-Ghali M, Lallemand-Breitenbach V. Abou-Ghali M, et al. Nucleus. 2024 Dec;15(1):2321265. doi: 10.1080/19491034.2024.2321265. Epub 2024 Feb 27. Nucleus. 2024. PMID: 38411156 Free PMC article. Review.
Serving as hubs in multiple signaling pathways, they influence cellular processes like senescence. Dysregulation of PML expression contributes to diseases, including cancer, highlighting their significance. Therapeutically, PML bodies are promising targets, e …
Serving as hubs in multiple signaling pathways, they influence cellular processes like senescence. Dysregulation of PML expression co …
Promyelocytic leukemia protein (PML) and stem cells: from cancer to pluripotency.
Vogiatzoglou AP, Moretto F, Makkou M, Papamatheakis J, Kretsovali A. Vogiatzoglou AP, et al. Int J Dev Biol. 2022;66(1-2-3):85-95. doi: 10.1387/ijdb.210154av. Int J Dev Biol. 2022. PMID: 34881785 Free article. Review.
The promyelocytic leukemia protein (PML) is the core organizer of cognate nuclear bodies (PML-NBs). ...In this review, we focus on the mechanisms orchestrated by PML and PML-NBs in cancer and healthy stem cells, from cell physiology to the regul …
The promyelocytic leukemia protein (PML) is the core organizer of cognate nuclear bodies (PML-NBs). ...In this review, we focu …
PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers.
Gentric G, Kieffer Y, Mieulet V, Goundiam O, Bonneau C, Nemati F, Hurbain I, Raposo G, Popova T, Stern MH, Lallemand-Breitenbach V, Müller S, Cañeque T, Rodriguez R, Vincent-Salomon A, de Thé H, Rossignol R, Mechta-Grigoriou F. Gentric G, et al. Cell Metab. 2019 Jan 8;29(1):156-173.e10. doi: 10.1016/j.cmet.2018.09.002. Epub 2018 Sep 20. Cell Metab. 2019. PMID: 30244973 Free PMC article.
High-grade serous ovarian cancer (HGSOC) remains an unmet medical challenge. Here, we unravel an unanticipated metabolic heterogeneity in HGSOC. ...Importantly, high-OXPHOS HGSOCs exhibit increased response to conventional chemotherapies, in which increased oxidative stres …
High-grade serous ovarian cancer (HGSOC) remains an unmet medical challenge. Here, we unravel an unanticipated metabolic heterogeneit …
Epstein-Barr virus and multiple sclerosis.
Soldan SS, Lieberman PM. Soldan SS, et al. Nat Rev Microbiol. 2023 Jan;21(1):51-64. doi: 10.1038/s41579-022-00770-5. Epub 2022 Aug 5. Nat Rev Microbiol. 2023. PMID: 35931816 Free PMC article. Review.
Epstein-Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-established causal role in several cancers. Recent studies have provided compelling epidemiological and mechanistic evidence for a causal role of EBV in multiple sclerosis (MS). ...How a ub …
Epstein-Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-established causal role in several cancers. Recen …
PML Differentially Regulates Growth and Invasion in Brain Cancer.
Tampakaki M, Oraiopoulou ME, Tzamali E, Tzedakis G, Makatounakis T, Zacharakis G, Papamatheakis J, Sakkalis V. Tampakaki M, et al. Int J Mol Sci. 2021 Jun 11;22(12):6289. doi: 10.3390/ijms22126289. Int J Mol Sci. 2021. PMID: 34208139 Free PMC article.
Recent evidence indicates dysregulation of the expression of the Promyelocytic Leukemia Protein (PML) in primary Glioblastoma samples. PML is implicated in various ways in cancer biology. ...In particular, PML overexpression suppresses cell proliferati …
Recent evidence indicates dysregulation of the expression of the Promyelocytic Leukemia Protein (PML) in primary Glioblastoma samples …
PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer.
Fracassi C, Ugge' M, Abdelhalim M, Zapparoli E, Simoni M, Magliulo D, Mazza D, Lazarevic D, Morelli MJ, Collas P, Bernardi R. Fracassi C, et al. Nucleic Acids Res. 2023 Nov 10;51(20):11024-11039. doi: 10.1093/nar/gkad819. Nucleic Acids Res. 2023. PMID: 37823593 Free PMC article.
The promyelocytic leukemia (PML) protein organizes nuclear aggregates known as PML nuclear bodies (PML-NBs), where many transcription factors localize to be regulated. ...We examined PML chromatin association in triple-negative breast cancer (TN …
The promyelocytic leukemia (PML) protein organizes nuclear aggregates known as PML nuclear bodies (PML-NBs), where many …
Targeting PML in triple negative breast cancer elicits growth suppression and senescence.
Arreal L, Piva M, Fernández S, Revandkar A, Schaub-Clerigué A, Villanueva J, Zabala-Letona A, Pujana M, Astobiza I, Cortazar AR, Hermanova I, Bozal-Basterra L, Arruabarrena-Aristorena A, Crespo JR, Valcarcel-Jimenez L, Zúñiga-García P, Canals F, Torrano V, Barrio R, Sutherland JD, Alimonti A, Martin-Martin N, Carracedo A. Arreal L, et al. Cell Death Differ. 2020 Apr;27(4):1186-1199. doi: 10.1038/s41418-019-0407-5. Epub 2019 Oct 1. Cell Death Differ. 2020. PMID: 31570853 Free PMC article.
We have previously reported that the Promyelocytic Leukemia protein (PML) is upregulated in triple negative breast cancer (TNBC) and it regulates cancer-initiating cell function, thus suggesting that this protein can be therapeutically targeted in combination …
We have previously reported that the Promyelocytic Leukemia protein (PML) is upregulated in triple negative breast cancer (TNB …
Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Bercier P, Wang QQ, Zang N, Zhang J, Yang C, Maimaitiyiming Y, Abou-Ghali M, Berthier C, Wu C, Niwa-Kawakita M, Dirami T, Geoffroy MC, Ferhi O, Quentin S, Benhenda S, Ogra Y, Gueroui Z, Zhou C, Naranmandura H, de Thé H, Lallemand-Breitenbach V. Bercier P, et al. Cancer Discov. 2023 Dec 12;13(12):2548-2565. doi: 10.1158/2159-8290.CD-23-0453. Cancer Discov. 2023. PMID: 37655965 Free PMC article.
PML nuclear bodies (NB) are disrupted in PML-RARA-driven acute promyelocytic leukemia (APL). ...These findings identify the structural basis for arsenic targeting of PML that could pave the way to novel cancer drugs. SIGNIFICANCE: Arsenic curative effe …
PML nuclear bodies (NB) are disrupted in PML-RARA-driven acute promyelocytic leukemia (APL). ...These findings identify the st …
[Progress of study on PML in cancer stem cell of hematologic malignancies].
Zhao HY, Li HM. Zhao HY, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2013 Jun;21(3):796-800. doi: 10.7534/j.issn.1009-2137.2013.03.050. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2013. PMID: 23815943 Review. Chinese.
Recent evidence indicates that PML involves in regulating multiple cell biological function, regulates self-renewal and maintains stable function in stem cell/cancer stem cell of multiple tissues, leading to drug resistance of cancer. This review summarizes t …
Recent evidence indicates that PML involves in regulating multiple cell biological function, regulates self-renewal and maintains sta …
Bioinformatics analyses of combined databases identify shared differentially expressed genes in cancer and autoimmune disease.
Sui Y, Li S, Fu XQ, Zhao ZJ, Xing S. Sui Y, et al. J Transl Med. 2023 Feb 10;21(1):109. doi: 10.1186/s12967-023-03943-9. J Transl Med. 2023. PMID: 36765396 Free PMC article.
RESULTS: The mRNA levels of signal transducer and activator of transcription 1 (STAT1), 2'-5'-oligoadenylate synthetase 1 (OAS1), 2'-5'-oligoadenylate synthetase like (OASL), and PML nuclear body scaffold (PML) were found to be differentially expressed in both IDC a …
RESULTS: The mRNA levels of signal transducer and activator of transcription 1 (STAT1), 2'-5'-oligoadenylate synthetase 1 (OAS1), 2'-5'-olig …
3,626 results